Jesse S Boehm from 11 Ridgewood Rd, West Concord, MA 01742, age 45, Phone: 978 369-7791

Signatures And Determinants Associated With Cancer And Methods Of Use Thereof
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US Patent:

20130323744, Dec 5, 2013
Filed:

Nov 30, 2011
Appl. No.:

13/990710
Inventors:

William C. Hahn - Newton MA, US
Pablo Tamayo - Hopkinton MA, US
Jesse S. Boehm - Jamaica Plain MA, US
Jill P. Mesirov - Belmont MA, US
Assignee:

The Broad Institute, Inc. - Cambridge MA
Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:

C12Q 1/68
US Classification:

435 612, 536 235, 436501, 435 79
Abstract:

The present invention provides methods of detecting cancer using biomarkers.

Compositions And Methods For Identifying Transforming And Tumor Suppressor Genes
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US Patent:

8178317, May 15, 2012
Filed:

May 1, 2008
Appl. No.:

12/150941
Inventors:

Thomas M. Roberts - Cambridge MA, US
Jean Zhao - Brookline MA, US
David E. Hill - Arlington MA, US
William C. Hahn - Newton MA, US
Jesse Boehm - Jamaica Plain MA, US
Assignee:

Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:

C12P 21/06
C07H 21/02
US Classification:

435 691, 536 231
Abstract:

Provided herein are nucleic acids, proteins, vectors, cells, kits, devices and methods useful for identifying regulatable proteins that are able to complement components of cellular signaling pathways. Also provided are compositions and methods using these complementing genes directly as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics. Further provided are methods for using changes caused by expression of the complementing genes to indirectly identify associated genes to be used as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics.

Methods And Compositions For Massively Parallel Variant And Small Molecule Phenotyping
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US Patent:

20200283843, Sep 10, 2020
Filed:

Mar 4, 2020
Appl. No.:

16/809458
Inventors:

- Cambridge MA, US
John Doench - Cambridge MA, US
JT Neal - Cambridge MA, US
Jesse Boehm - Cambridge MA, US
Oana Ursu - Cambridge MA, US
International Classification:

C12Q 1/6869
C12N 15/10
Abstract:

The present invention provides methods and tools for analyzing genetic interactions. The subject matter is generally directed to single-cell genomics and proteomics, including methods of performing genome-wide CRISPR perturbation screens and determining gene expression phenotypes.