Michael E. Hepperle - Boston MA, US Julie Fields Liu - Lexington MA, US Francois Soucy - Stoneham MA, US Prakash Raman - Acton MA, US Jeremy D. Little - Wakefield MA, US Paul E. Fleming - Wellesley MA, US Dominic Reynolds - Cambridge MA, US Geraldine C. B. Harriman - Charlestown RI, US
Jeremy D. Little - Wakefield MA, US Shomir Ghosh - Brookline MA, US Sean Harrison - Belmont MA, US Amy M. Elder - Arlington MA, US Christelle C. Renou - Somerville MA, US Kenneth G. Carson - Princeton NJ, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 215/38
US Classification:
546159
Abstract:
Disclosed are CRTH2 inhibitors represented by Structural Formula (I):.
Beta-Carbolines Useful For Treating Inflammatory Disease
Michael Hepperle - Boston MA, US Julie Liu - Lexington MA, US Francois Soucy - Stoneham MA, US Yingchun Ye - Durham NH, US Robert Murray - Medford MA, US Raman Prakash - Acton MA, US Jeremy Little - Wakefield MA, US Alfredo Castro - Winchester MA, US Hormoz Mazdiyasni - Douglas MA, US Paul Fleming - Wellesley MA, US Dominic Reynolds - Cambridge MA, US
This invention provides beta-carboline compounds of formula I: wherein Ring A is a substituted pyridinyl, pyrimidinyl, morpholinyl, piperidinyl, piperazinyl, pyrrolidinyl, pyranyl, tetrahydrofuranyl, cyclohexyl, cyclopentyl or thiomorpholinyl ring and R, Rand Rare as described in the specification. The compounds are IKK-2 inhibitors that are useful for treating IKK-2-mediated diseases such as inflammatory diseases and cancer.
Beta-Carbolines Useful For Treating Inflammatory Disease
Michael E. Hepperle - San Diego CA, US Julie Fields Liu - Lexington MA, US Francois Soucy - Stoneham MA, US Yingchun Ye - Belmont MA, US Robert S. Murray - Framingham MA, US Raman Prakash - Acton MA, US Jeremy D. Little - Wakefield MA, US Alfredo Castro - Winchester MA, US Hormoz Mazdiyasni - Marlborough MA, US Paul E. Fleming - Wellesley MA, US Dominic Reynolds - Stoneham MA, US
Tune Studios - Chief Executive Officer (2012) Flux Visual Lab - Managing Director Laguna Music - Director Greenhouse Studio - Manager (2012)
Jeremy Little
Work:
Incredible Technologies Inc. - ComElectronic Technician & Gaming Field Service Technician (2000)
Relationship:
In_a_relationship
About:
Hello there! :o)
Tagline:
Really needs another vacation SOON...
Jeremy Little
Work:
Looking for Work
Education:
Monash University - Business Management
Tagline:
Yeah, it's like that. Got a problem with it?
Jeremy Little
Work:
O'Reilly Automotive - Merchandiser (2012)
Jeremy Little
Education:
St patricks cathedral
Jeremy Little
About:
I like stuff. Some stuff I like are boats, guacamole, nylon string guitars, and ninjas. I think there are no situations in life that a funny hat can not improve. If I could afford it, I would wear a n...
Tagline:
Yay!!1
Jeremy Little
About:
I'm into Nirvana and the Flaming Lips. I like Kevin Smith, Guy Ritchie, Quentin Tarantino, and Stanley Kubrick movies. Xbox360 and Xbox Live.
Others Named Jeremy Little. Jeremy Little Jeremy Little Jeremy-Maxim Little- Prinz Klauza Jeremy Little Amanda Jeremy Little Jeremy Little Jeremy Little ...
Not a day goes by when I dont miss Tim Russerts boyish enthusiasm, steadfast support, and treasured phone calls, as we discussed everything from politics to baseball. The pain of losing Tim, Jeff Gralnick, David Bloom, Jeremy Little, Eric Wishnie and Mark Harrington from our ranks ... as well as m