Jennifer D Hill

Author:

Jennifer Leigh Hill

ISBN #:

0132626012

Author:

Jennifer A. Hill

ISBN #:

0820322784

Author:

Jennifer A. Hill

ISBN #:

0820322792

Author:

Jennifer Hill

ISBN #:

0141001801

Author:

Jennifer Hill

ISBN #:

0521867061

Author:

Jennifer Hill

ISBN #:

0670887242

Author:

Jennifer Hill

ISBN #:

0734021852

Address:

2000 E Arapaho Rd APT 22214, Richardson, TX 75081

Phone:

972 470-0247

VIN:

JTDKB20U973220747

Make:

TOYOTA

Model:

PRIUS

Year:

2007

US Patent:

6602975, Aug 5, 2003

Filed:

Oct 22, 2001

Appl. No.:

10/021508

Inventors:

Jeffrey A. Hubbell - Zumikon, CH
Chandrashekhar P. Pathak - Austin TX
Amarpreet S. Sawhney - Lexington MA
Neil P. Desai - Los Angeles CA
Jennifer L. Hill - Pearland TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C08G 6308

US Classification:

528354, 528356, 528359, 528361, 528363, 525 541, 525 542, 525408, 525411, 525413, 525415, 428357, 428364, 428394, 428480, 424426, 424489

Abstract:

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

US Patent:

6632446, Oct 14, 2003

Filed:

Oct 23, 2000

Appl. No.:

09/694836

Inventors:

Jeffrey A. Hubbell - Austin TX
Chandrashekhar P. Pathak - Waltham MA
Amarpreet S. Sawhney - Newton MA
Neil P. Desai - Los Angeles CA
Jennifer L. Hill - Austin TX
Syed F. A. Hossainy - Austin TX

Assignee:

The Board of Regents, University of Texas System - Austin TX

International Classification:

A61F 200

US Classification:

424423, 424422, 424426, 424484, 424486, 424487, 424488, 424 7808, 424 7837, 424 931, 424 937, 424 941, 435177, 435178, 435180, 435182, 435382, 435395, 514 2, 530812, 530813, 530815, 530817

Abstract:

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, and coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules. A medical condition can be treated by applying to a site a polymerization initiator, then applying a substantially water-soluble, degradable macromer of at least 200 mw and having at least two crosslinkable substituents, and polymerizing the macromer to form a polymeric material that can adhere two surfaces together, be an immunoisolation barrier, prevent adhesion of the site to another surface, or contain a biologically active material for delivery or to provide the polymeric material with resistance to bacterial growth or a decrease in inflammatory response. A biocompatible substrate can be coated by applying a mixture of the macromer of at least 400 mw and an initiator and polymerizing. The initiator may be applied to the substrate before the macromer.

US Patent:

7153519, Dec 26, 2006

Filed:

Jun 25, 2003

Appl. No.:

10/607247

Inventors:

Jeffrey A. Hubbell - Zurich, CH
Chandrashekhar P. Pathak - Austin TX, US
Amarpreet S. Sawhney - Lexington MA, US
Neil P. Desai - Los Angeles CA, US
Jennifer L. Hill - Pearland TX, US
Syed F. A. Hossainy - Fremont CA, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61F 2/00
C12N 11/04
A61K 38/00
A61K 9/14
A61K 31/74

US Classification:

424423, 424426, 424484, 424486, 424 7808, 424 7837, 424 931, 424 937, 435178, 435180, 435182, 435395, 514 2, 530812, 530813, 530815, 530817

Abstract:

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules.

US Patent:

58437436, Dec 1, 1998

Filed:

Jun 6, 1995

Appl. No.:

8/467815

Inventors:

Jeffrey A. Hubbell - Austin TX
Chandrashekhar P. Pathak - Waltham MA
Amarpreet S. Sawhney - Newton MA
Neil P. Desai - Los Angeles CA
Jennifer L. Hill - Austin TX
Syed F. A. Hossainy - Austin TX

Assignee:

Board of Regents, The university of Texas System - Austin TX

International Classification:

A61K 948
B05D 700
C12N 1100
C12N 1102

US Classification:

435177

Abstract:

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules.

US Patent:

58342745, Nov 10, 1998

Filed:

Jun 6, 1995

Appl. No.:

8/467693

Inventors:

Jeffrey A. Hubbell - Austin TX
Chandrashekhar P. Pathak - Waltham MA
Amarpreet S. Sawhney - Newton MA
Neil P. Desai - Los Angeles CA
Jennifer L. Hill - Austin TX
Syed F. A. Hossainy - Austin TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C12N 1102
C12N 1104
C08J 716
A61K 4732

US Classification:

435177

Abstract:

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules.

US Patent:

56268637, May 6, 1997

Filed:

Jan 27, 1995

Appl. No.:

8/379848

Inventors:

Jeffrey A. Hubbell - Austin TX
Chandrashekhar P. Pathak - Waltham MA
Amarpreet S. Sawhney - Newton MA
Neil P. Desai - Los Angeles CA
Jennifer L. Hill - Austin TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61K 958
C08G 6308

US Classification:

424426

Abstract:

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

US Patent:

63069229, Oct 23, 2001

Filed:

Jan 26, 2000

Appl. No.:

9/492011

Inventors:

Jeffrey A. Hubbell - Austin TX
Chandrashekhar P. Pathak - Waltham MA
Amarpreet S. Sawhney - Newton MA
Neil P. Desai - Los Angeles CA
Jennifer L. Hill - Austin TX

Assignee:

Boards of Regents, The University of Texas System - Austin TX

International Classification:

C08G 6308
C08G 6700

US Classification:

522 71

Abstract:

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

US Patent:

54100160, Apr 25, 1995

Filed:

Mar 1, 1993

Appl. No.:

8/022687

Inventors:

Jeffrey A. Hubbell - Austin TX
Chandrashekhar P. Pathak - Waltham MA
Amarpreet S. Sawhney - Newton MA
Neil P. Desai - Los Angeles CA
Jennifer L. Hill - Austin TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C08G 6308
C08G 6700
A61K 958

US Classification:

528354

Abstract:

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.