Jayesh R Dharia from Landenberg, PA, age 63

Positively Charged Membrane
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US Patent:

6780327, Aug 24, 2004
Filed:

Dec 12, 2001
Appl. No.:

09/914163
Inventors:

Xiaosong Wu - Pensacola FL
Chung-Jen Hou - Pensacola FL
Jayesh Dharia - Pensacola FL
Peter Konstantin - Heinade, DE
Yujing Yang - Pensacola FL
Assignee:

Pall Corporation - East Hills NY
International Classification:

B01D 6114
US Classification:

210660, 210488, 210490, 21050021, 21050037, 21050038, 2105021, 427245, 521 27
Abstract:

The present invention provides a positively charged microporous membrane having a protein binding capacity about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.

Positively Charged Membrane
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US Patent:

6851561, Feb 8, 2005
Filed:

Jul 15, 2004
Appl. No.:

10/891098
Inventors:

Xiaosong Wu - Pensacola FL, US
Chung-Jen Hou - Pensacola FL, US
Jayesh Dharia - Pensacola FL, US
Peter Konstantin - Boulder CO, US
Yujing Yang - Newton MA, US
Assignee:

Pall Corporation - East Hills NY
International Classification:

B01D063/14
B01D063/06
B01D069/10
B01D069/12
B01D071/56
US Classification:

210490, 210435, 210488, 2104931, 21049701, 21050021, 21050037, 21050038
Abstract:

The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.

Positively Charged Membrane
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US Patent:

7094347, Aug 22, 2006
Filed:

Jan 18, 2005
Appl. No.:

11/035950
Inventors:

Xiaosong Wu - Pensacola FL, US
Chung-Jen Hou - Pensacola FL, US
Jayesh Dharia - Pensacola FL, US
Peter Konstantin - Boulder CO, US
Yujing Yang - Newton MA, US
Assignee:

Pall Corporation - East Hills NY
International Classification:

B01D 63/00
B01D 63/08
B01D 39/16
B01D 29/46
B01D 63/14
US Classification:

21032184, 21032188, 21050035, 21050037, 21050038, 210488, 210490, 2104931, 21032186
Abstract:

The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.

Positively Charged Membrane
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US Patent:

7223341, May 29, 2007
Filed:

Jul 6, 2006
Appl. No.:

11/480977
Inventors:

Xiaosong Wu - Pensacola FL, US
Chung-Jen Hou - Pensacola FL, US
Jayesh Dharia - Pensacola FL, US
Peter Konstantin - Boulder CO, US
Yujing Yang - Newton MA, US
Assignee:

Pall Corporation - East Hills NY
International Classification:

B01D 39/14
B01D 63/00
US Classification:

21050037, 21050021, 21050035, 21050038, 21050041, 210490
Abstract:

The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.

Positively Charged Membrane
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US Patent:

7396465, Jul 8, 2008
Filed:

May 1, 2007
Appl. No.:

11/742749
Inventors:

Xiaosong Wu - Pensacola FL, US
Chung-Jen Hou - Pensacola FL, US
Jayesh Dharia - Pensacola FL, US
Peter Konstantin - Boulder CO, US
Yujing Yang - Newton MA, US
Assignee:

Pall Corporation - East Hills NY
International Classification:

B01D 71/26
B01D 71/28
B01D 71/40
B01D 71/44
B01D 71/06
US Classification:

21050021, 21050037, 21050038, 21050041
Abstract:

The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.

Jayesh R Dharia