James W Sweeney

US Patent:

47880694, Nov 29, 1988

Filed:

Mar 27, 1987

Appl. No.:

7/032129

Inventors:

Guillermo A. Iacobucci - Atlanta GA
James G. Sweeney - Atlanta GA
James G. King - Atlanta GA

Assignee:

The Coca-Cola Company - Atlanta GA

International Classification:

C07K 506
A23L 1236

US Classification:

426548

Abstract:

The present invention relates to L-aspartyl-3-(bicycloalkyl)-L-alanine alkyl esters having high sweetness intensity, of the formula: ##STR1## wherein R. sup. 1 is a substituted or an unsubstituted bicycloalkyl ring, said ring having 7 to 8 carbon atoms, the 2-position ring carbon atom is bound to the alamine moiety, the two carbon atoms of the ring that are vicinal to the 2-position carbon are each substituted by a hydrogen or lower alkyl, the total number of alkyl groups bound to the vicinal carbons is less than three, and R. sup. 2 is methyl. The "2R" configuration enantiomers of the R. sup. 1 group are especially preferred. In preferred embodiments of the invention, R. sup. 1 is a bornyl, camphanyl, norbornyl, 1-methylnorbornyl, 3-methylnorbornyl, 7,7-dimethylnorbornyl, bicyclo [2. 2. 2] octyl, or pinanyl ring. The compounds of the invention, or edible salts thereof, can be used for sweetening edible products such as foods and beverages.