James B O'Connor

US Patent:

7763582, Jul 27, 2010

Filed:

Feb 21, 2007

Appl. No.:

12/280085

Inventors:

Sheldon Suton Lin - Chatham NJ, US
Ankur Gandhi - Metuchen NJ, US
James Patrick O'Connor - Fanwood NJ, US
Loay A. Al-Zube - Zarga, JO
Joseph Benevenia - Montclair NJ, US
J. Russell Parsons - Perth Amboy NJ, US

Assignee:

University of Medicine and Dentistry Of New Jersey - New Brunswick NJ

International Classification:

A61K 38/28

US Classification:

514 3, 514 4

Abstract:

A method of promoting bone healing in a non-diabetic patient in need thereof by locally administering a therapeutically effective amount of insulin to the patient. A drug delivery device, which includes insulin and a pharmaceutically acceptable carrier, wherein the device is adapted for localized administration of insulin to a patient in need thereof is also presented.

US Patent:

8554608, Oct 8, 2013

Filed:

Mar 23, 2011

Appl. No.:

13/069507

Inventors:

James O'Connor - Brooklyn NY, US

International Classification:

G06Q 99/00

US Classification:

705 13, 705 11, 705 711

Abstract:

An embodiment of the disclosed technology is an in-taxi customer selection system. The selection system is placed in a plurality of taxis in the form of a device which includes a touch-screen display map of a surrounding location of each taxi. An indicator of at least one future rider desiring a taxi is exhibited anonymously on each display map. The indicator exhibits only a location, and thus, lacks destination data or information about the potential rider other than his or her location of pickup. In this manner, all picked up riders are anonymous to the driver and discrimination against the rider is actually less than in the prior art, since the appearance of the rider cannot be judged before the ride is accepted. Sensors within the touch-screen display receive a selection of an indicator on one of the display maps from a driver of one of the taxis using this system. The selected indicator is then removed from all other display maps, if shown on any at the time, and the driver is sent a confirmation of said selection.

US Patent:

20110105959, May 5, 2011

Filed:

Aug 20, 2010

Appl. No.:

12/860818

Inventors:

James Patrick O'Connor - Newark NJ, US

Assignee:

ACCELALOX, INC. - Menlo Park CA

International Classification:

A61N 7/00
A61K 38/20
A61K 38/19
A61K 38/18
A61K 38/22
A61K 38/29
A61K 31/40
A61K 31/197
A61K 31/454
A61K 31/41
A61K 31/353
A61P 19/08
A61P 19/10

US Classification:

601 2, 424 852, 424 851, 514 89, 514 91, 514 96, 514 118, 514 88, 514 82, 514423, 514563, 514321, 514567, 514381, 514456, 514428

Abstract:

Methods for promoting osteogenesis to accelerate or enhance bone fracture healing, treat bone defects, and enhance bone formation are disclosed. The methods rely on in vivo or ex vivo modulation of an arachidonic acid metabolic or signaling pathway in general, and, in particular, utilize 5-lipoxygenase inhibitors, leukotriene A4 hydrolase inhibitors, and/or leukotriene B4 receptor antagonists. These molecules can be delivered alone or in combination with one or more agents that inhibit bone resorption, regulate calcium resorption from bone, enhance bone accumulation, enhance bone formation, induce bone formation, impair growth of microorganisms, reduce inflammation, and/or reduce pain.

US Patent:

20110124717, May 26, 2011

Filed:

Nov 5, 2010

Appl. No.:

12/940995

Inventors:

James Patrick O'Connor - Newark NJ, US

Assignee:

ACCELALOX, INC. - Menlo Park CA

International Classification:

A61K 31/7088
A61K 31/05
A61K 31/12
A61P 19/00
A61P 19/08
C12N 5/071

US Classification:

514 44 R, 514734, 514688, 435325

Abstract:

Methods for promoting osteogenesis to accelerate or enhance bone fracture healing, treat bone defects, and enhance bone formation are disclosed. The methods modulate an arachidonic acid metabolic or signaling pathway in general, and, in particular, utilize 5-lipoxygenase inhibitors. These molecules can be delivered alone or in combination with one or more agents that inhibit bone resorption, regulate calcium resorption from bone, enhance bone accumulation, enhance bone formation, induce bone formation, impair growth of microorganisms, reduce inflammation, and/or reduce pain.

US Patent:

20130171094, Jul 4, 2013

Filed:

Jan 14, 2011

Appl. No.:

13/522075

Inventors:

Sheldon Suton Lin - Chatham NJ, US
David Naisby Paglia - New Britain CT, US
James Patrick O'Connor - Fanwood NJ, US
Eric Breitbart - South Orange NJ, US
Joseph Benevenia - Montclair NJ, US

Assignee:

UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY - Somerset NJ

International Classification:

A61K 31/555
A61K 45/06

US Classification:

424 852, 514492, 514 76, 514 86, 514 85, 514 82, 514 88, 514 91, 514 89, 514 96, 514 81, 514 118, 514 167, 424 851, 514 92, 424 937, 556 42

Abstract:

This invention provides a method of promoting bone healing by locally administering a vanadium-based insulin mimetic agent to a patient in need thereof. The invention also provides a new use of insulin-mimetic vanadium compounds for manufacture of medicaments for accelerating bone-healing processes. In addition, the invention also encompasses a bone injury treatment kit suitable for localized administration of insulin-mimetic vanadium compounds or compositions thereof to a patient in need of such treatment.

US Patent:

59730730, Oct 26, 1999

Filed:

Apr 6, 1998

Appl. No.:

9/055419

Inventors:

Shao-Hua Guo - West Goshen PA
Donald L. Lickei - Wayne PA
Michael J. Morgan - Spring City PA
James M. O'Connor - Cheshire CT

Assignee:

ARCO Chemical Technology, L.P. - Greenville DE

International Classification:

C08J 300
C08K 320
C08L 7500
C08F 830

US Classification:

525123

Abstract:

Two-component polyurethane coating formulations comprising an aqueous dispersion of a polyisocyanate and a neutralized, water-dispersible resin are disclosed. The neutralized, water-dispersible resin incorporates recurring units of an allylic alcohol or an alkoxylated allylic alcohol. These low-VOC formulations use commercial polyisocyanates and ordinary mixing techniques. The uniquely uniform distribution of hydroxyl groups in the resin contributes to an excellent overall balance of coating properties from the 2K system, including high gloss, hardness, impact resistance, flexibility, weatherability, and chemical resistance.

US Patent:

58611932, Jan 19, 1999

Filed:

Aug 14, 1998

Appl. No.:

/134610

Inventors:

Stephen L. Goldstein - Glen Mills PA
James M. O'Connor - Branford CT
Donald L. Lickei - Wayne PA
Henry G. Barnowski - Durham CT
Willard F. Burt - Bristol CT
Ronald S. Blackwell - Waterbury CT

Assignee:

Arco Chemical Technology, L.P. - Greenville DE

International Classification:

B05D 302
C08G 1806
C08G 1810
C08G 1880

US Classification:

4273855

Abstract:

The present invention relates to the preparation and use of novel polyurethane polyuretidione crosslinking agents in solvent and water borne coatings systems. These polyuretidione polyurethanes are characterized by their relatively low solution viscosity, and the ability to provide a relatively high crosslink density in the final, cured film, and thereby, coatings with the excellent physical properties and resistance to chemical and environmental exposure of known polyurethane systems without the potential for worker exposure to toxic isocyanates. This invention also relates to a process for the production of these polyuretidiones and their use in pseudo-one and two component coating compositions.

US Patent:

58146890, Sep 29, 1998

Filed:

Aug 29, 1997

Appl. No.:

8/920494

Inventors:

Stephen L. Goldstein - Glen Mills PA
James M. O'Connor - Branford CT
Donald L. Lickei - Wayne PA
Henry G. Barnowski - Durham CT
Willard F. Burt - Bristol CT
Ronald S. Blackwell - Waterbury CT

Assignee:

Arco Chemical Technology, L.P. - Greenville DE

International Classification:

C08G 1806
C08G 1810
C08G 1880

US Classification:

524 86

Abstract:

The present invention relates to the preparation and use of novel polyurethane polyuretidione crosslinking agents in solvent and water borne coatings systems. These polyuretidione polyurethanes are characterized by their relatively low solution viscosity, and the ability to provide a relatively high crosslink density in the final, cured film, and thereby, coatings with the excellent physical properties and resistance to chemical and environmental exposure of known polyurethane systems without the potential for worker exposure to toxic isocyanates. This invention also relates to a process for the production of these polyuretidiones and their use in pseudo-one and two component coating compositions.