James E Forrester

Author:

James W. Forrester

ISBN #:

0874514533

Author:

James A. Forrester

ISBN #:

0070929653

Author:

James R. Forrester

ISBN #:

0534602797

Author:

James R. Forrester

ISBN #:

0536575126

Author:

James R. Forrester

ISBN #:

0536579776

US Patent:

20110280834, Nov 17, 2011

Filed:

Jan 15, 2010

Appl. No.:

13/144881

Inventors:

James S. Forrester - Malibu CA, US
Raj R. Makkar - Los Angeles CA, US
Eduardo Marbán - Beverly Hills CA, US

Assignee:

CEDARS-SINAI MEDICAL CENTER - Los Angeles CA

International Classification:

A61K 35/12
A61P 9/00
A61K 38/18
A61K 38/00

US Classification:

424 931, 514 164, 514 89

Abstract:

Methods for treating an injured cardiac tissue in a subject are provided herein. Methods for improving survival, engraftment and proliferation of stem cells in a cardiac tissue are provided. Also provided are methods for generating cardiac cells. Further provided are compositions for generating cardiac cells in a subject.

US Patent:

RE310972, Dec 7, 1982

Filed:

Jun 17, 1980

Appl. No.:

6/160384

Inventors:

Ran Vas - Encino CA
James S. Forrester - Malibu CA
George A. Diamond - Los Angeles CA

Assignee:

Cardiokinetics, Inc. - Seattle WA

International Classification:

A61B 502

US Classification:

128687

Abstract:

An apparatus and method for the detection of movement of body tissues and, more particularly, movements of segments of the heart muscle and method for a noninvasive technique for the detection of coronary and arterial abnormalities. The apparatus includes a probe, preferably in the form of a detector plate, utilizing electric field measurement for detection of movements of a nearby segment of the body tissue, as for example, a segment of the heart muscle. The detector plate is coupled to a variable-frequency oscillator and phase-lock system for measuring capacitive change used to shift the phase of the oscillator when the detector is placed with respect to a certain body tissue. The apparatus employs its own unique system of timing heart movement in that the detector is capable of sensing a signal having a low frequency component which provides information regarding tissue movement. The detector also senses a high frequency component of the signal which represents closure of heart valves and thereby establishes a timing cycle for heart movement so that contraction and relaxation movements of the heart tissue can be measured in terms of the timing cycle of the heart. A filter in the apparatus separates the high frequency components from the low frequency components so that information regarding relaxation and contraction may be recorded simultaneously with the timing cycle of the heart movement.

US Patent:

42954738, Oct 20, 1981

Filed:

May 24, 1979

Appl. No.:

6/042247

Inventors:

George Diamond - Los Angeles CA
James Forrester - Malibu CA
Michael Hirsch - Pacific Palisades CA
Ran Vas - Encino CA

International Classification:

D61N 500

US Classification:

178695

Abstract:

An apparatus and method in which the amount of movement of a boundary in one or more dimensions on a dynamically movable structure or a series of sequential visual representations of said structure is measured. The boundary movement is measured by the degree of shiftable movement between light and dark areas. The motion may be analyzed and quantified in terms of linear motion or area change and an electrical analog of such motion is generated in format suitable for recordation by conventional reproducing or display mechanisms, as for example, a conventional chart recorder. In one embodiment, movement in one dimension, e. g. a linear dimension, is detected but not necessarily quantified. In another embodiment, the movement in the linear dimension is detected and measured so as to provide a quantification thereof. In a further embodiment the movement is measured in at least two dimensions to provide quantification of area changes.

US Patent:

41823150, Jan 8, 1980

Filed:

Jul 21, 1977

Appl. No.:

5/817708

Inventors:

Ran Vas - Encino CA
James S. Forrester - Malibu CA
George A. Diamond - Los Angeles CA

International Classification:

A61B 502

US Classification:

128687

Abstract:

An apparatus and method for the detection of movement of body tissues and, more particularly, movements of segments of the heart muscle and method for a noninvasive technique for the detection of coronary and arterial abnormalities. The apparatus includes a probe, preferably in the form of a detector plate, utilizing electric field measurement for detection of movements of a nearby segment of the body tissue, as for example, a segment of the heart muscle. The detector plate is coupled to a variable-frequency oscillator and phase-lock system for measuring capacitive change used to shift the phase of the oscillator when the detector is placed with respect to a certain body tissue. The apparatus employs its own unique system of timing heart movement in that the detector is capable of sensing a signal having a low frequency component which provides information regarding tissue movement. The detector also senses a high frequency component of the signal which represents closure of heart valves and thereby establishes a timing cycle for heart movement so that contraction and relaxation movements of the heart tissue can be measured in terms of the timing cycle of the heart. A filter in the apparatus separates the high frequency components from the low frequency components so that information regarding relaxation and contraction may be recorded simultaneously with the timing cycle of the heart movement.