Hiroshi Inoue ( , Inoue Hiroshi, March 30, 1932 December 29, 1989) was a Japanese botanist specializing in bryology. The standard botanical author ...
Name / Title
Company / Classification
Phones & Addresses
Hiroshi Inoue Chief Executive Officer
Mitsubishi Nuclear Energy Systems Inc Commercial Physical Research · Business Services Ret New/Used Automobiles · Business Services, Nec, Nsk · Electrical Contractor
1001 19 St N, Arlington, VA 22209 13860 Ballantyne, Charlotte, NC 28277 703 908-8040
Hiroshi Inoue President
Canon US Life Sciences Biotechnology · Medical Research/Development · Noncommercial Research Organization
9800 Medical Ctr Dr SUITE C-120, Rockville, MD 20850 9800 Med Ctr Dr, Rockville, MD 20850 301 762-7070
Jetro - Japan External Trade Organization
Overseas Business Development Partner
Cyest Corporation.
Japan Executive Advisor
Canon Usa Jul 2010 - Jul 2014
Senior Fellow
University of Maryland - Robert H. Smith School of Business Jul 2010 - Jul 2014
Professor of the Practice
Canon U.s. Life Sciences Jan 2005 - Jun 2010
President and Chief Executive Officer and Chief Technology Officer
Education:
University of Maryland 2013 - 2017
University of Maryland 2011 - 2016
University of Maryland 2011 - 2012
The Sanno University 2006 - 2007
Master of Business Administration, Masters
Osaka University 1973 - 1977
Bachelors, Bachelor of Science, Chemistry
Skills:
Dna R&D Medical Devices Technology Transfer Microfluidics Cell Commercialization Biochemistry Genomics Start Ups Pcr Matlab Technology Evaluation Product Development Entrepreneurship Metal Complex Compound Gene Sequence Ip Multimedia Subsystem Contents Server Network Communications Digital Image Processing Iso/Iec 14496 Felloelectric Liquid Crystal Display Liquid Crystal Display Polarizer Plate Flat Panel Display Mpeg 4 High Resolution Melt Curve Analysis In Line Pcr Blood Collection Blood Sample Phagocyte In Vitro
Toru Takahashi - Tokyo, JP Hiroshi Inoue - Bethesda MD, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
International Classification:
C12Q 1/68 C12M 1/00
US Classification:
435 6, 4352831
Abstract:
The invention provides an apparatus that can be used in methods of preparing, amplifying, detecting, and/or optionally selecting for further analysis the genomic material from an organism for the rapid detection and/or classification of an organism in a sample (e. g. , screening for, identifying, quantifying, and/or optionally further analyzing, e. g. , sequencing, the genomic material of the organism). The invention further provides methods of using the apparatus, e. g. , in combination with novel SGP primers for improved use in waveform-profiling methods of DNA amplification. It is an object of the invention to provide an apparatus for fully automated analysis of genomic material, and multiple methods of using the apparatus that are beneficial to society, e. g. , the apparatus may be used in methods of screening for, identifying, quantifying, and/or selecting genomic material for further analysis (e. g. , sequencing) in relation to monitoring a source for the presence of contaminating organisms.
Kenton C. Hasson - Gaithersburg MD, US Gregory A. Dale - Gaithersburg MD, US Hiroshi Inoue - Bethesda MD, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
International Classification:
C12Q 1/68 C12P 19/34
US Classification:
435 6, 435 912
Abstract:
The present invention relates to methods for amplifying nucleic acids in micro-channels. More specifically, the present invention relates to methods for performing a real-time polymerase chain reaction (PCR) in a continuous-flow microfluidic system and to methods for monitoring real-time PCR in such systems.
Method And Molecular Diagnostic Device For Detection, Analysis And Identification Of Genomic Dna
Hiroshi Inoue - Bethesda MD, US Ivor T. Knight - Arlington VA, US Gregory A. Dale - Gaithersburg MD, US Rita R. Colwell - Bethesda MD, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
International Classification:
C12M 1/34 C12M 3/00
US Classification:
4352872
Abstract:
At least one exemplary embodiment of the invention is directed to a molecular diagnostic device that comprises a cartridge configured to eject samples comprising genomic material into a microfluidic chip that comprises an amplification area, a detection area, and a matrix analysis area.
Kenton C. Hasson - Germantown MD, US Gregory A. Dale - Gaithersburg MD, US Hiroshi Inoue - Bethesda MD, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
International Classification:
C12M 3/00 C12M 1/34
US Classification:
4352865, 4352872
Abstract:
The present invention relates to methods for amplifying nucleic acids in micro-channels. More specifically, the present invention relates to methods for performing a real-time polymerase chain reaction (PCR) in a continuous-flow microfluidic system and to methods for monitoring real-time PCR in such systems.
Methods And Systems For Microfluidic Dna Sample Preparation
Weidong Cao - Rockville MD, US Hiroshi Inoue - Bethesda MD, US Kevin Louder - Rockville MD, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
International Classification:
C12Q 1/68 C12M 1/00 C07H 21/00
US Classification:
435 61, 4352831, 536 221, 536 254
Abstract:
The present invention relates to methods and systems for microfluidic DNA sample preparation. More specifically, embodiments of the present invention relate to methods and systems for the isolation of DNA from patient samples on a microfluidic device and use of the DNA for downstream processing, such as performing amplification reactions and thermal melt analysis on the microfluidic device.
Ray Tsao - Rockville MD, US Hiroshi Inoue - Bethesda MD, US Shulin Zeng - Gaithersburg MD, US Brian Murphy - Baltimore MD, US Kenton C. Hasson - Germantown MD, US
An interface cartridge for a microfluidic chip, with microfluidic process channels and fluidic connection holes at opposed ends of the process channels, provides ancillary fluid structure, including fluid flow channels and input and/or waste wells, which mix and/or convey reaction fluids to the fluidic connection holes and into the process channels of the microfluidic chip.
Microfluidic Devices With Integrated Resistive Heater Electrodes Including Systems And Methods For Controlling And Measuring The Temperatures Of Such Heater Electrodes
Takayoshi Hanagata - Rockville MD, US Hiroshi Inoue - Bethesda MD, US Gregory A. Dale - Gaithersburg MD, US Kenton C. Hasson - Gaithersburg MD, US
Assignee:
CANON U.S. LIFE SCIENCES, INC. - Rockville MD
International Classification:
C12P 19/34 C12M 1/34
US Classification:
435 912, 4352891, 4352861
Abstract:
The invention relates to methods and devices for control of an integrated thin-film device with a plurality of microfluidic channels. In one embodiment, the microfluidic device includes a microfluidic chip comprising a first zone having a plurality of microfluidic channels and a second zone having a plurality of microfluidic channels, wherein the microfluidic channels in the first and second zones are in fluid communication. The microfluidic device further comprising a thin-film heater in thermal communication with each of the microfluidic channels in the first and second zones. The microfluidic device also includes a control system configured to independently control the temperature of each of the thin-film heaters using pulse width modulation (PWM) control signals that are optimized for each of the thin-film heaters.
Device And Method For Digital Multiplex Pcr Assays
Ivor T. Knight - Arlington VA, US Hiroshi Inoue - Bethesda MD, US
Assignee:
CANON U.S. LIFE SCIENCES, INC. - Rockville MD
International Classification:
C40B 20/04 C40B 20/08 C40B 60/06
US Classification:
506 4, 506 6, 506 38
Abstract:
A method and device for digital multiplex PCR assays employ a microfluidic chip for performing real-time, continuous flow PCR within microchannels of the chip. A stream of sample material is introduced into each microchannel and alternating boluses of assay-specific reagents and buffer are introduced into the stream to form sequentially configured test boluses. A PCR procedure is performed on the test boluses followed by a thermal melt procedure. During the thermal melt procedure, fluorescent output is detected and fluorescence vs temperature data is collected and compared to expected normal correlations. The results, positive or negative, are converted to digital format, with positive results designated as “1” and negative results designated as “0”, or vice versa.