Harold I Jacob

US Patent:

6517538, Feb 11, 2003

Filed:

Oct 15, 1999

Appl. No.:

09/419451

Inventors:

Harold Jacob - Cedarhurst NY 11516
Yoed Rabin - Cedarhurst NY 11516

International Classification:

A61B 1818

US Classification:

606 47, 606113

Abstract:

An apparatus, method and kit are provided for removal of polyps, especially pursuant to colonoscopic surgery. The apparatus includes an endoscopic guide tube, a heating element, a power transmitting element traversing through the guide tube and communicating with the heating element, at least one temperature sensor for measuring temperature near the polyp, and optionally an external monitor for receiving temperature data from the sensor and then activating a power source for adjusting the temperature of the heating element in a controlled manner. An operator/physician can manually set the temperature range and temperature increase rate, but preferentially this is achieved automatically through a pre-programmed computer schedule.

US Patent:

7018629, Mar 28, 2006

Filed:

Jan 22, 2003

Appl. No.:

10/347877

Inventors:

Harold Jacob - Cedarhurst NY, US
Samuel Adler - Lawrence NY, US

Assignee:

The Bio Balance Corporation - New York NY

International Classification:

A01N 63/00
C12N 1/20
C12N 1/00

US Classification:

424 9348, 435849, 4352528

Abstract:

Pharmaceutical compositions of probiotic strains and uses thereof for treating inflammatory bowel disease.

US Patent:

7829029, Nov 9, 2010

Filed:

Mar 29, 2007

Appl. No.:

11/730005

Inventors:

Jona Zumeris - Haifa, IL
Harold Jacob - Cedarhurst NY, US

Assignee:

NanoVibronix, Inv. - Nesher

International Classification:

A61L 2/025

US Classification:

422127, 422 20, 422128, 600466, 604 22

Abstract:

A urinary catheter clip-on device applies surface acoustic waves of Rayleigh-Lamb and/or Love type to a urinary catheter for preventing biofilms on the catheter surfaces. The bacteria is forced to move relative to the vibrating catheter surface. The amplitudes of bacteria vibrations are in nanometer range. The relative motion of bacteria results in bacteria quorum sensing, and disrupts the bacteria attachment process. The method is preventive as surface acoustic waves create low acoustic energy and bacteria is not killed.

US Patent:

20030158460, Aug 21, 2003

Filed:

Jan 11, 2002

Appl. No.:

10/043491

Inventors:

Chaim Sukenik - D.N. Shimshon, IL
Harold Jacob - Cedarhurst NY, US
Marc Berridge - Solon OH, US

International Classification:

A61N005/00
A61F002/06
A61L002/00

US Classification:

600/001000, 623/001440, 427/002240

Abstract:

A device, which comprises a surface layer that has incorporated therein at least one radioactive nuclide. The surface layer is a self-assembled layer, particularly an anchored SAM that is selected from the group consisting of monolayers or films anchored by siloxane, thiol, amine or phosphonate. The surface layer may be formed of a radioactive material that has been activated to induce radioactivity therein after its final formation. The device may comprise a chemically functionalized SAM incorporating radionuclides attached at the surface of the device. The device may be a temporary or permanent therapeutic implant, such as a stent.

US Patent:

20070213645, Sep 13, 2007

Filed:

Feb 26, 2007

Appl. No.:

11/710616

Inventors:

Jona Zumeris - Haifa, IL
Harold Jacob - Cedarhurst NY, US
Hanan Raskin - Kfar Saba, IL
Gera Kratysh - Haifa, IL
Yanina Zumeris - Haifa, IL

International Classification:

A61H 1/00
A61F 2/02
A61F 2/82

US Classification:

601046000, 623011110, 623001420, 607116000

Abstract:

Methods and systems are provided for treatment of medical devices using surface acoustic waves (SAW) of Rayleigh, “pseudo” Rayleigh and Lamb type. In some embodiments, use of such SAW is controlled such that relative velocity of bacteria is achieved wherein the vibration amplitude of the bacteria is smaller than a Z-potential repulsive zone of the bacteria, thus preventing biofilm formation on the medical devices. In some embodiments, systems of the present invention are powered by body movements, and may also provide a feedback loop for control of parameters. In some embodiments, the medical devices of the present invention are comprised of piezoelectric material, and act as self-actuators for the system.

US Patent:

20070232962, Oct 4, 2007

Filed:

Feb 26, 2007

Appl. No.:

11/710615

Inventors:

Jona Zumeris - Haifa, IL
Harold Jacob - Cedarhurst NY, US
Hanan Raskin - Kfar Saba, IL
Gera Kratysh - Haifa, IL
Yanina Zumeris - Haifa, IL

International Classification:

A61H 1/00
A61B 8/00

US Classification:

601002000, 600439000

Abstract:

Methods and devices for treating skin include a skin-contacting portion, an actuator and a processor, wherein activation of the actuator causes surface acoustic waves of Rayleigh, “pseudo” Rayleigh types to be produced on the skin around the actuator. In a location which is under the actuator, the actuator produces tension and repulsion of skin particles. These surface acoustic waves can be used to provide treatment to the skin, including wound healing, non-adhesion of bandages, reduced infection, reduced pain and cosmetic enhancements. The skin-contacting portion may be a patch or bandage, a glove, a hand-held device, or any other suitable configuration. The actuator is incorporated into the skin-contacting portion.

US Patent:

20130030329, Jan 31, 2013

Filed:

Dec 14, 2010

Appl. No.:

13/521060

Inventors:

Jona Zumeris - Haifa, IL
Harold Jacob - Cedarhurst NY, US

International Classification:

A61H 23/02
A61N 7/00

US Classification:

601 2, 601 47

Abstract:

An apparatus, system and methods thereof for generating an acoustic lubrication effect along a surface of an in-dwelling medical device that is in contact with a vital tissue in a subject are provided. The vibrations comprise: Hz range cylindrical surface vibrations; or kHz range surface acoustic wave (SAW) vibrations; or a combination thereof. The vibrations create an acoustic lubrication effect that may reduce pain or discomfort in a subject when the apparatus is used with an indwelling medical device. The vibrations may enhance tactile sensation when the medical device is a shoe pad.