The invention generally relates to microneedle devices, methods of making same, pharmaceutical compositions comprising same, and methods of treating a disease comprising administering same. Specifically, the disclosed microneedle devices comprise a plurality of biocompatible microneedles having one or more of: (i) a curved, discontinuous, undercut, and/or perforated sidewall; (ii) a sidewall comprising a breakable support; and (iii) a cross-section that is non-circular and non-polygonal. The microneedles may also be tiered. Alternatively, the microneedles may be tiered. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Polymeric Microneedles And Rapid Additive Manufacturing Of The Same
- Chape; Hill NC, US Gregory R. Robbins - Redwood City CA, US Ashley R. Johnson - Coppell TX, US
International Classification:
A61M 37/00 A61B 5/15
Abstract:
The invention generally relates to microneedle devices, methods of making same, pharmaceutical compositions comprising same, and methods of treating a disease comprising administering same. Specifically, the disclosed microneedle devices comprise a plurality of biocompatible microneedles having one or more of: (i) a curved, discontinuous, undercut, and/or perforated sidewall; (ii) a sidewall comprising a breakable support; and (iii) a cross-section that is non-circular and non-polygonal. The microneedles may also be tiered. Alternatively, the microneedles may be tiered. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Massachusetts General Hospital Infectious Disease Inpatient Clinic 55 Fruit St, Boston, MA 02114 617 726-3812 (phone), 617 726-7653 (fax)
Education:
Medical School Boston University School of Medicine Graduated: 1990
Procedures:
Vaccine Administration
Conditions:
HIV Infection Acute Bronchitis Acute Pancreatitis Acute Pharyngitis Acute Sinusitis
Languages:
English Spanish
Description:
Dr. Robbins graduated from the Boston University School of Medicine in 1990. He works in Boston, MA and specializes in Infectious Disease. Dr. Robbins is affiliated with Massachusetts General Hospital.
Industrial Health Services 1001 Cherry Blossom Way, Georgetown, KY 40324 502 868-4961 (phone), 502 868-4998 (fax)
Premise Health 25 Atlantic Ave, Erlanger, KY 41018 859 746-7992 (phone), 859 372-3898 (fax)
Education:
Medical School University of Kentucky College of Medicine Graduated: 1984
Languages:
English Spanish
Description:
Dr. Robbins graduated from the University of Kentucky College of Medicine in 1984. He works in Georgetown, KY and 1 other location and specializes in Family Medicine. Dr. Robbins is affiliated with Georgetown Community Hospital.
The first prosecution under Ohios fetal homicide statute was in 1996, when Gregory Robbins beat his wife, who was 8 months pregnant, causing the death of her unborn child. Outside Ohio, several high-profile criminal cases have led to the enactment of state fetal homicide laws. In North Carolina, la