Graham Ansell - Millbury MA, US Todd Blythe - Georgetown MA, US Andrew Jones - Needham MA, US Benjamin Littler - San Diego CA, US Adam Looker - Somerville MA, US Philip Nyce - Millbury MA, US John Snoonian - Bolton MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 413/10 C07D 307/08
US Classification:
548236, 549475
Abstract:
The present invention relates to processes for preparing biaryl ureas derivatives and analogs thereof. The invention also provides compounds useful as intermediates in the processes of the present invention. The process is useful for preparing compounds that inhibit IMPDH.
Processes For Preparing Biaryl Ureas And Analogs Thereof
Graham Ansell - Millbury MA, US Todd Blythe - Georgetown MA, US Andrew Jones - Needham MA, US Benjamin Littler - San Diego CA, US Adam Looker - Somerville MA, US Philip Nyce - Millbury MA, US John Snoonian - Bolton MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 413/12
US Classification:
548236, 549200
Abstract:
The present invention relates to processes for preparing biaryl ureas derivatives and analogs thereof. The invention also provides compounds useful as intermediates in the processes of the present invention. The process is useful for preparing compounds that inhibit IMPDH.
Adrian D. Hobson - Shrewsbury MA, US Kevin P. Cusack - Holden MA, US Eric C. Breinlinger - Charlton MA, US Graham K. Ansell - Millbury MA, US Robert H. Stoffel - Harvard MA, US Kevin R. Woller - Antioch IL, US Pintipa Grongsaard - Whippany NJ, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/4245 C07D 271/06
US Classification:
514364, 548131
Abstract:
Novel oxadiazole compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions as agonists or antagonists of the S1P family of G protein-coupled receptors for treating diseases associated with modulation of S1P family receptor activity, in particular by affording a beneficial immunosuppressive effect are disclosed.
Octahydropentalene Compounds As Chemokine Receptor Antagonists
Dawn M. George - Charlton MA, US Lu Wang - Northborough MA, US Biqin Li - Northborough MA, US Anna M. Ericsson - Shrewsbury MA, US Graham K. Ansell - Millbury MA, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A01N 43/42 A61K 31/44 C07D 221/02
US Classification:
514299, 546112
Abstract:
The present invention is directed to novel compounds of Formula (I).
Sphingosine-1-Phosphate Receptor Agonist And Antagonist Compounds
Grier A. Wallace - Sterling MA, US Eric C. Breinlinger - Charlton MA, US Kevin P. Cusack - Holden MA, US Thomas D. Gordon - Medway MA, US Adrian D. Hobson - Shrewsbury MA, US Martin E. Hayes - Lowell MA, US Graham K. Ansell - Millbury MA, US Pintipa Grongsaard - Shrewsbury MA, US
The present invention is directed to novel, potent, and selective agents, which are agonists or antagonists of the one or more of the individual receptors of the S1P receptor family. The compounds of the invention are useful as therapeutics for treating medical conditions associated with agonism or antagonism of the individual receptors of the S1P receptor family.
Octahydropentalene Compounds As Chemokine Receptor Antagonists
Dawn M. George - Charlton MA, US Lu X. Wang - Northborough MA, US Biqin Li - Southborough MA, US Anna M. Ericsson - Shrewsbury MA, US Graham K. Ansell - Millbury MA, US
Assignee:
AbbVie Inc. - North Chicago IL
International Classification:
A01N 43/42 A61K 31/44 C07D 221/02
US Classification:
514299, 546112
Abstract:
The present invention is directed to novel compounds of Formula (I).
General Business Counseling Patent Prosecution Life Sciences
ISLN:
921965235
University:
Imperial College London England, 1995; Imperial College London England, 1995; The University of Sussex England, Ph.D., 2001; University of North London England, 1994; University of North London England, 1994; University of North London England, 1994
Resumes
Independent Translation And Localization Professional