Gideon E Bollag from 168 Alice Ln, Orinda, CA 94563, age 62

Name / Title

Company / Classification

Phones & Addresses

Gideon E. Bollag
Chief Executive Officer

Kinkead Communications, Inc
Communication Services

1414 Greenwich St, San Francisco, CA 94109

Raf-Mek-Erk Pathway Inhibitors To Treat Cancer
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US Patent:

7307071, Dec 11, 2007
Filed:

Dec 3, 2002
Appl. No.:

10/308721
Inventors:

John F. Lyons - Moraga CA, US
Gideon Bollag - Hercules CA, US
Assignee:

Onyx Pharmaceuticals, Inc - Emeryville CA
International Classification:

A61K 31/025
A61K 31/03
A61K 31/13
A61K 31/075
A61K 31/08
A61K 31/17
A61K 31/33
US Classification:

514183, 514588, 514591, 514596, 514597, 514619, 514620, 514647, 514660, 514670, 514672, 514673, 514716, 514717, 514718, 514719, 514721, 514722, 514747, 514749, 514751
Abstract:

Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia, and which cancer is preferably resistant to the inhibition of the Bcr-Abl tyrosine kinase, imatinib.

Compounds And Methods For Kinase Modulation, And Indications Therefor
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US Patent:

7863288, Jan 4, 2011
Filed:

Jun 21, 2006
Appl. No.:

11/473347
Inventors:

Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Oakland CA, US
Chao Zhang - Moraga CA, US
Jiazhong Zhang - Foster City CA, US
James Tsai - Vallejo CA, US
Klaus-Peter Hirth - San Francisco CA, US
Gideon Bollag - Orinda CA, US
Wayne Spevak - Berkeley CA, US
Hanna Cho - Oakland CA, US
Samuel J. Gillette - Oakland CA, US
Shenghua Shi - San Diego CA, US
Assignee:

Plexxikon, Inc. - Berkeley CA
International Classification:

C07D 471/02
C07D 491/02
C07D 498/02
C07D 513/02
A01N 43/42
A61K 31/44
US Classification:

514300, 546113
Abstract:

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Compounds And Methods For Kinase Modulation, And Indications Therefor
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US Patent:

8143271, Mar 27, 2012
Filed:

Aug 23, 2011
Appl. No.:

13/216200
Inventors:

Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Oakland CA, US
Chao Zhang - Moraga CA, US
Jiazhong Zhang - Foster City CA, US
James Tsai - Vallejo CA, US
Klaus-Peter Hirth - San Francisco CA, US
Gideon Bollag - Orinda CA, US
Hanna Cho - Oakland CA, US
Assignee:

Plexxikon Inc. - Berkeley CA
International Classification:

C07D 471/02
C07D 491/02
C07D 498/02
C07D 513/02
A01N 43/42
A61K 31/44
US Classification:

514300, 546113
Abstract:

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Compounds And Methods For Kinase Modulation, And Indications Therefor
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US Patent:

8415469, Apr 9, 2013
Filed:

Nov 10, 2009
Appl. No.:

12/616079
Inventors:

Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Oakland CA, US
Gaston Habets - Pleasant Hill CA, US
Marika Nespi - Berkeley CA, US
Chao Zhang - Moraga CA, US
Jiazhong Zhang - Foster City CA, US
Yong-Liang Zhu - Fremont CA, US
Rebecca Zuckerman - Alameda CA, US
Brian West - San Francisco CA, US
Yoshisa Suzuki - El Sobrante CA, US
Jianming Tsai - Vallejo CA, US
Klaus-Peter Hirth - San Francisco CA, US
Gideon Bollag - Orinda CA, US
Wayne Spevak - Berkeley CA, US
Hanna Cho - Oakland CA, US
Samuel J. Gillette - Oakland CA, US
Guoxian Wu - Palo Alto CA, US
Hongyao Zhu - Berkeley CA, US
Shenghua Shi - San Diego CA, US
Assignee:

Plexxikon Inc. - Berkeley CA
International Classification:

C07D 413/14
C07D 401/14
C07D 471/04
C07F 7/02
US Classification:

544127, 544362, 546 14, 546113
Abstract:

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Compounds And Methods For Kinase Modulation, And Indications Therefor
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US Patent:

8470818, Jun 25, 2013
Filed:

Oct 18, 2010
Appl. No.:

12/906980
Inventors:

Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Oakland CA, US
Chao Zhang - Moraga CA, US
Jiazhong Zhang - Forster City CA, US
Jianming Tsai - Vallejo CA, US
Klaus-Peter Hirth - San Francisco CA, US
Gideon Bollag - Orinda CA, US
Wayne Spevak - Berkeley CA, US
Hanna Cho - Oakland CA, US
Samuel J. Gillette - Oakland CA, US
Shenghua Shi - San Diego CA, US
Assignee:

Plexxikon Inc. - Berkeley CA
International Classification:

A61K 31/535
US Classification:

5142345, 51425304, 514300, 435184, 546113
Abstract:

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Novel Nucleic Acids And Polypeptides Related To A Farnesyl-Directed Endopeptidase
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US Patent:

20030013181, Jan 16, 2003
Filed:

Apr 19, 1999
Appl. No.:

09/294455
Inventors:

YUN-JUNG CHOI - UNION CITY CA, US
ANNE K. NORTH - PLEASANT HILL CA, US
GEORGE A. MARTIN - BERKELEY CA, US
GIDEON BOLLAG - HERCULES CA, US
International Classification:

C12N009/64
C07H021/04
C12P021/02
C12N005/06
US Classification:

435/226000, 435/069100, 435/320100, 435/325000, 536/023200
Abstract:

The present invention relates to a mammalian farnesyl-directed endopeptidase, especially obtainable from a human or mouse. The polypeptide and corresponding nucleic acid are useful in a variety of ways, such as for diagnostic probes, in assays to identify agents which interfere with the endopeptidase activity and its expression, and for the screening of agents for treating cancer and other pathways in which the polypeptide is involved.

Methods And Compositions For Treating Abnormal Cell Growth Related To Unwanted Guanine Nucleotide Exchange Factor Activity
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US Patent:

20030203464, Oct 30, 2003
Filed:

Jan 18, 2002
Appl. No.:

10/054435
Inventors:

Gideon Bollag - Hercules CA, US
Anne Crompton - San Francisco CA, US
Anne North - Pleasant Hill CA, US
William Roscoe - San Francisco CA, US
Sanju Sharma - Berkeley CA, US
International Classification:

C12N009/22
C07H021/04
C12P021/02
C12N005/06
US Classification:

435/199000, 435/069100, 435/325000, 435/320100, 536/023200
Abstract:

Methods and compositions are described that affect the GTPase activity of members of the Ras superfamily, preferably Rac, such compositions include guanine nucleotide exchange factors that modulate the GTPase activity, preferably in the presence of GEF enhancers, exemplary guanine nucleotide exchange factors being Rac-GEF and Tiam-1, which are encoded by certain nucleic acid sequences that are herein described, along with uses for the guanine nucleotide exchange factors and the nucleic acid sequences including screening for ligands which recognize Rac-GEF, regulators of Rac-GEF activity, and methods of treating pathological conditions associated or related to a Ras superfamily GTPase, including Rac.

Pde5A Crystal Structure And Uses
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US Patent:

20050048573, Mar 3, 2005
Filed:

Feb 3, 2004
Appl. No.:

10/771833
Inventors:

Dean Artis - Kensington CA, US
Gideon Bollag - Orinda CA, US
Graeme Card - Oakland CA, US
Fernando Martin - Toronto, CA
Michael Milburn - Cary NC, US
Kam Zhang - Walnut Creek CA, US
International Classification:

G01N033/53
G01N033/543
US Classification:

435007100, 436518000
Abstract:

A crystal structure of PDE5A is described that was determined by X-ray crystallography. The use of PDE5A crystals and strucural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate PDE5A.