Gerd W. Michel - Princeton NJ Wilbur L. Bryan - Somerset NJ Elizabeth Bryan - Arlington VA
Assignee:
E. R. Squibb & Sons, Inc. - Princeton NJ
International Classification:
C07H 1708 A01N 4304 A61K 3500 C07G 300
US Classification:
536 65
Abstract:
A unique four-solvent system comprising methanol, dimethylformamide, methylene chloride and water is employed to provide an improved process for the purification and crystallization of amphotericin B.