George X Bakale

US Patent:

42245664, Sep 23, 1980

Filed:

Mar 3, 1977

Appl. No.:

5/773831

Inventors:

George Bakale - Cleveland Heights OH
Earle C. Gregg - Chagrin Falls OH

International Classification:

G01N 2700

US Classification:

324 71R

Abstract:

This is a highly sensitive detection system to be used in conjunction with liquid chromatography to determine the extremely fast rates of electron attachment to electrophilic compounds in nonpolar solvents. The system integrates pulse radiolysis, liquid state electronics and liquid chromatography and is designated Pulsed Electron Attachment Conductivity-Liquid Chromatography or PEAC-LC. The detector system is responsive only to electrophilic compounds. Since electrophilicity has been correlated with carcinogenicity, the PEAC-LC detector system is a primary screening monitor for carcinogens.