Ganeshsingh A Thakur from Cambridge, MA, age 84

Novel Bicyclic Cannabinoids
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US Patent:

20070135388, Jun 14, 2007
Filed:

Dec 12, 2006
Appl. No.:

11/609580
Inventors:

Alexandros Makriyannis - Watertown MA, US
Spyridon Nikas - Waltham MA, US
Atmaram Khanolkar - Coventry RI, US
Ganeshsingh Thakur - Waltham MA, US
Dai Lu - Boston MA, US
International Classification:

A61K 31/665
A61K 31/5375
A61K 31/426
A61K 31/421
A61K 31/12
US Classification:

514100000, 514237800, 514365000, 514374000, 514439000, 514463000, 514690000
Abstract:

Bicyclic-cannabinoids and methods of preparation and use are presented. These compounds, when administered in a therapeutically effective amount to an individual or animal, results in a sufficiently high level of that compound in the individual or animal to cause a physiological response. The physiological response may be useful to treat a number of physiological conditions.

Cannabinergic Compounds And Uses Thereof
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US Patent:

20210101878, Apr 8, 2021
Filed:

Dec 11, 2020
Appl. No.:

17/119836
Inventors:

- Boston MA, US
Spyridon P. Nikas - Newton MA, US
Ganeshsingh A. Thakur - Boston MA, US
Rishi Sharma - Revere MA, US
Shashank Kulkarni - Billerica MA, US
International Classification:

C07D 311/80
C07D 405/12
C07D 407/04
C07C 57/58
C07C 255/57
C07D 493/04
Abstract:

Disclosed are compounds and compositions that modulate cannabinoid receptors, methods of modulating cannabinoid receptors, and methods of treating various disorders related to the modulation of cannabinoid receptors. This disclosure is directed to methods of treating cannabinoid dependence, neuropathy, inflammation, glaucoma, a neurodegenerative disorder, a motor function disorder, a gastrointestinal disorder, hypothermia, emesis, loss of appetite, or anorexia associated with AIDS.

Novel Cannabinergic Compounds And Uses Thereof
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US Patent:

20190185443, Jun 20, 2019
Filed:

Jan 7, 2019
Appl. No.:

16/241424
Inventors:

- Boston MA, US
Ganeshsingh A. Thakur - Cambridge MA, US
Rishi Sharma - Revere MA, US
International Classification:

C07D 311/80
C07D 493/04
C07C 255/57
C07D 405/12
C07D 407/04
C07C 57/58
Abstract:

Disclosed are compounds and compositions that modulate cannabinoid receptors, methods of modulating cannabinoid receptors, and methods of treating various disorders related to the modulation of cannabinoid receptors. This disclosure is directed to methods of treating cannabinoid dependence, neuropathy, inflammation, glaucoma, a neurodegenerative disorder, a motor function disorder, a gastrointestinal disorder, hypothermia, emesis, loss of appetite, or anorexia associated with AIDS.

2-Cycloalkyl Resorcinol Cannabinergic Ligands
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US Patent:

20150274623, Oct 1, 2015
Filed:

Oct 17, 2013
Appl. No.:

14/436865
Inventors:

- Boston, MA, US
Marsha R. D'Souza - Boston MA, US
Shama Bajaj - Somerville MA, US
Spyridon P. Nikas - Waltham MA, US
Ganeshsingh A. Thakur - Cambridge MA, US
Assignee:

Northeastern Uiversity - Boston MA
International Classification:

C07C 39/23
C07D 339/06
C07D 309/06
C07C 43/178
C07C 245/24
C07D 295/192
C07D 295/096
C07C 49/603
C07C 69/16
C07C 255/36
Abstract:

The present invention relates to novel 2-cycloalkyl resorcinol compounds; to pharmaceutical compositions comprising the compounds; and to methods of preparing the compounds and uses thereof. The disclosed compounds can bind to and modulate the cannabinoid receptors and thus, they are specific ligands for these receptors. The invented compounds, when administered in a therapeutically effective amount to an individual or animal, results in a sufficiently high level of that compound in the individual or animal to cause a physiological response. The physiological response may be useful to treat a number of physiological conditions.

Ganeshsingh A Thakur