Eric T. Fung - Los Altos CA, US John P. Cooke - Palo Alto CA, US Xiao-Ying Meng - Fremont CA, US Fujun Zhang - Fremont CA, US
Assignee:
Vermillion, Inc. - Austin TX Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G01N 33/53
US Classification:
435 71, 435 72, 436518
Abstract:
This invention provides biomarkers whose concentrations in blood plasma are associated with the presence or absence of PAD in the patient from whom the plasma sample is taken. The invention also provides biomarkers for distinguishing between PAD patients who are long claudicators and PAD patients who are not. In addition, the invention provides methods for identifying additional biomarkers, methods for detecting the biomarkers in patients, and methods for identifying agents, including pharmaceutical agents, which interact with the biomarkers and are useful for preventing or treating PAD in patients.
Zhen Zhang - Dayton MD, US Daniel Chan - Clarksville MD, US Eric Fung - Los Altos CA, US Zheng Wang - Fremont CA, US Fujun Zhang - Fremont CA, US
International Classification:
G01N 33/574 G06F 19/00
US Classification:
435007230, 702019000
Abstract:
The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
Panel Of Biomarkers For Peripheral Arterial Disease
Eric T. Fung - Los Altos CA, US John Cooke - Palo Alto CA, US Fujun Zhang - Fremont CA, US Andrew Wilson - Glen Iris, AU
Assignee:
Vermillion, Inc. - Fremont CA The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G01N 33/00 G06F 19/00
US Classification:
436 86, 702 19
Abstract:
The invention provides biomarkers including β-2-microglobulin, Cystatin C, hsCRP and glucose as well as methods for using the biomarkers for diagnosing and/or assessing the risk of peripheral artery disease in a subject. In some embodiments, the subject being tested may be suffering from or at risk of other circulatory diseases, including coronary artery disease. Hemoglobin A1c or other proxies for measuring glucose levels may be substituted for or measured in addition to glucose in the context of the present invention.
Biomarker For Ovarian Cancer Ctap3-Related Proteins
Zhen Zhang - Dayton MD, US Daniel W. Chan - Clarksville MD, US Eric T. Fung - Los Altos CA, US Zheng Wang - Fremont CA, US Fujun Zhang - Fremont CA, US
Assignee:
The Johns Hopkins University - Baltimore MD Vermillion, Inc. - Fremont CA
The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
Biomarker For Ovarian Cancer Ctap3-Related Proteins
- Austin TX, US - Baltimore MD, US ERIC T. FUNG - LOS ALTOS CA, US ZHENG WANG - FREMONT CA, US FUJUN ZHANG - FREMONT CA, US
Assignee:
Vermillion, Inc. - Austin TX The Johns Hopkins University - Baltimore MD
International Classification:
G01N 33/574
US Classification:
506 9, 506 18
Abstract:
The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
Caastle
Data Scientist and Machine Learning Lead
Robert Half
Data Scientist -- Technician Lead
Education:
Stanford University 2014
Stanford University 2013
University of Wisconsin - Madison 2000
Master of Science, Masters
Beijing Agricultural University 1996
Master of Science, Masters
Shandong Agricultural University 1990
Bachelors, Bachelor of Science
Skills:
Writing Compare Neural Networks Statisticians Consulting Market Web Marketing Discover Survival Analysis Model Building Vendors Windows Fungal Conventional Bacterial Undergraduate Perl Matlab Biotechnology Linear Programming Lasso Finance Time Series Analysis San Minitab Thesis Amazon Construction Vector Convex Optimization Design of Experiments Plots Product Management Keywords Clusters Detection Lda Search Management Search Engines Design Simulations Massive Experimental Design User Interface Design Science Spc Machine Learning Resume Patents Statistics Ongoing Support Svm Transparent Metrics Data Mining Interpreting Data Beijing Pfizer Density Linux Algorithms Methodology Factor Trees S Plus Guidance Stochastic Methods Networking Forecasting Troubleshooting System Languages Cell Cluster Healthcare Data Monitoring Visualization Tests Drive Results Boosting Validation Asset Allocation Reports Knowledge Discovery Strategy Mixed Model Hadoop Hotels Apache Logistic Regression Pharmaceutical Sciences Artificial Intelligence Strategies Mixed Tables Variable Testing Risk Management Commercial Software Population Genetics Contamination Intelligent Agents Redwood A/B Testing Extract Robust Research System Monitoring Stakeholders Garch Statistical Modeling Spark Operational Support Word Processing Anova R&D Pragmatic Analysis Statistical Package Process Simulation Data Visualization Ensemble Semantic Analysis Statistical Tools Laboratory Concepts R Project Estimation Yahoo C Coordination Retail Predictive Modeling Moving Applications Financial Modeling Data Analysis Assay Development Graduate Level Universities Modeling Gams Wikipedia Evidence Project Bidding Quantitative Analyses Scientific Institutions Partial Operations Author Clinical Data Suite Html Bootstrap Marketing Big Data Vba Mining Process Monitoring Statistical Analysis Tools Business Intelligence Unsupervised Learning Forest Sql Ubuntu Surface Programming Experience Silicon Graphics Genetics Analytics Unix Empirical Analytical Software Hypothesis Testing Spss Responsibility Internal Audit User Interface Search Algorithms E Commerce International Nlp Intelligence Data Science Code Classification Network Optimization Process Modeling Open Source Teaching Pca Plot Scala Internal Customers Parametric Diagnostics Business Insights Data Quality Regression Testing Cart Software Sas Kernel Berkeley Java Simulated Annealing Extend Rate Pharmaceutics Topic Manufacturing Hive Libraries China Python Sampling Optimization Scientists Technical Issues Cluster Analysis Conceptual Modeling Bagging Automatic Unified Communications Evaluation Process Optimization Databases