Frank Toppo

Author:

Frank R. Toppo

ISBN #:

0932209009

US Patent:

20040067266, Apr 8, 2004

Filed:

Oct 7, 2002

Appl. No.:

10/265372

Inventors:

Frank Toppo - Las Vegas NV, US

International Classification:

A61K035/78

US Classification:

424/730000, 424/747000, 424/765000, 424/777000

Abstract:

The delivery of St. John's Wort coupled separately with Natural Peppermint, Banana and Green Apple flavors via the nasal and or buccal mucosa in a ph appropriate solution, in homeopathic doses, is effective as an anorexant.

US Patent:

60489030, Apr 11, 2000

Filed:

May 3, 1994

Appl. No.:

8/238214

Inventors:

Frank Toppo - Las Vegas NV

International Classification:

A61K 3105

US Classification:

514733

Abstract:

The level of heavy density lipoproteins (HDL) in the blood of a human subject can be in eased by administering dosages of between 50 and 1,000 milligrams of trans-resveratrol to the subject daily. This same dosage reduces the level of light density lipoproteins (LDL) in the blood of the subject. By increasing the blood level of HDL and decreasing the blood level of LDL in the subject, the risk of hypercholesterolemia in the subject is reduced.

US Patent:

59858605, Nov 16, 1999

Filed:

Jun 7, 1994

Appl. No.:

8/255100

Inventors:

Frank Toppo - Las Vegas NV

International Classification:

A61K 3160

US Classification:

514159

Abstract:

Compositions for pain relieving non-steroidal anti-inflammatory drugs and/or medicaments such as ibuprofen, methotrexate, capsaicin, diphenhydramine, aspirin, methyl-nicotinate and other medicaments largely soluble in oil, alcohol, and/or water, are produced for transdermal delivery. The composition is manufactured by admixing an appropriate amount of oil surfactant with an appropriate amount of pharmaceutically approved co-solubilizer alcohol to establish a non aqueous phase. The oil surfactant may be a polyethoxylated oil such as castor oil. The co-solubilizer solubilizer may be isopropyl alcohol or virtually any other alcohols except for methanol. Thereafter, an appropriate amount of distilled water is slowly added to the homogeneous or non-aqueous phase to further reduce viscosity. The final admixture is a clear, oil-continuous solution having a viscosity no greater than 850 centistokes as measured by the VST Hoppler method at 25 degrees Celsius. The composition produced has the capacity to affect the individual surface skin cells (corneocytes) and allow the passage of medicaments to sub-dermal afflicted areas deep within the skin.