Corporate Law • Business Formation • Foreign Investment • Liquidations • Trademark Registration • International Bankruptcy • Hotel and Resort Development
Francisco J. Alvarez - Lindenhurst IL Kathy M. O'Connor - Round Lake Beach IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31195 A61K 3119 A61K 3800
US Classification:
514 19
Abstract:
A pharmaceutical tablet composition comprising a compound of the formula (II): ##STR1## wherein R. sub. 1 is 4-piperazinyl, 1-methyl-4-piperazinyl, 1-methyl-1-oxo-4-piperazinyl, 2-oxo-4-piperazinyl, 4-morpholinyl, 4-thiomorpholinyl or 1-methyl-4-homopiperazinyl; R. sub. 2 is benzyl, p-methoxybenzyl, 2-phenylethyl, 1-naphthylmethyl or 2-naphthylmethyl; R. sub. 3 is 4-thiazolyl, 2-amino-4-thiazolyl, 2-thiazolyl, 5-thiazolyl, 1-pyrazolyl, 3-pyrazolyl, 1-imidazolyl, n-propyl, isopropyl, CH. sub. 3 S-- or CH. sub. 3 SCH. sub. 2 --; R. sub. 4 is loweralkyl or cyclopropyl; R. sub. 5 is hydrogen or loweralkyl; and X is CH. sub. 2 or NH; or a pharmaceutically acceptable salt, ester or prodrug thereof, and a pharmaceutically acceptable organic polycarboxylic acid. In addition, the tablet composition can further comprise one or more pharmaceutically acceptable non-ionic surfactants.
Pramod K. Gupta - Gurnee IL Francisco J. Alvarez - Lindenhurst IL Susan J. Semla - Evanston IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 920
US Classification:
424464
Abstract:
A pharmaceutical tablet containing a therapeutically active compound and between 5% and about 20% by weight of an oil, preferably selected from vegetable, mineral, animal and edible oils, as well as a method for preparing such tablets. Such tablets provide for the controlled release of the therapeutically active compound from the tablet and also enhance the stability of some therapeutically active compounds.
Compositions of a quinolone carboxylic acids useful for oral or parenteral administration to a human or veterinary patient are disclosed which comprise quinolone carboxylic acid--metal ion--acid complexes in combination with a physiologically acceptable carrier and having a pH of about 4 to about 10, as well as a method for their production and use in treatment. Such compositions are found to cause unexpectedly low levels of vein irritation upon intravenous administration.
Dr. Alvarez graduated from the Michigan State University College of Human Medicine in 2001. He works in Chico, CA and specializes in Internal Medicine. Dr. Alvarez is affiliated with Enloe Medical Center.
Last years bold prediction: Francisco Alvarez will be the best catcher in the National League. J.T. Realmuto owned that title for a while, and William Contreras, Sean Murphy and Will Smith provide stout competition. But Alvarez showed long enough flashes of excellence both at and behind the plate l
Date: Mar 27, 2025
Category: Sports
Source: Google
Undervalued hitters for 2025 fantasy baseball: Time to buy Austin Wells or Pavin Smith?
the last week, while those are two-catcher formats that skew the data, it does suggest that he's no longer a target for the "wait on catcher" crowd. However, with Francisco Alvarez, Sean Murphy, and Tyler Stephenson banged up, Wells is likely my favorite mid-tier catching target in drafts right now.
Date: Mar 20, 2025
Category: Sports
Source: Google
Mets vs. Dodgers: The OMG Mets head into offseason of uncertainty as 2024 thrill ride comes to an end — 'It doesn't feel real'
When reporters entered the clubhouse, catcher Francisco Alvarez was hunched over on the floor, his back against a wall, tears swelling in his eyes. Outfielder Brandon Nimmo consoled him, offering words of encouragement. Lindor, still in his baseball pants, sat on the ground next to Iglesias locker
Date: Oct 21, 2024
Category: Sports
Source: Google
Mets' season ends with NLCS Game 6 heartbreaker to Dodgers
In the final moments, all of the Mets were at the top step of the dugout, arms on the railing, just in case they pulled out one last miracle. None came. It all ended with Francisco Alvarez grounding out to second base against Blake Treinen.
Date: Oct 21, 2024
Category: Sports
Source: Google
Mets vs. Dodgers: Live score, updates, lineups and TV info for NLCS Game 3
With one out, J.D. Martinez walked, Jose Iglesias singled on a grounder that was bobbled by Tommy Edman and Tyrone Taylor walked to load the bases. But Francisco Alvarez was frozen on an outside fastball and Francisco Lindor swung through a high fastball.
Date: Oct 16, 2024
Category: Sports
Source: Google
Olney: Inside the wildest day of the MLB regular season
to take Diaz out of the game, but Diaz talked his way back in, for the bottom of the ninth -- OK, he kind of demanded to pitch the ninth, and his manager gave in to the All-Star closer. When Diaz got the final out, he turned and spiked his glove on the mound before hugging catcher Francisco Alvarez.
It would be surprising to see the Mets do anything other than sticking with what got them here: Francisco Alvarez, Pete Alonso, Jose Iglesias, Mark Vientos, and Francisco Lindor on the infield; Brandon Nimmo, Tyrone Taylor, and Starling Marte in the outfield; J.D. Martinez at DH; Luis Torrens, Luisa
Date: Oct 01, 2024
Category: Sports
Source: Google
MLB playoffs 2024: With momentum and a bit of magic, Mets roll to wild-card Game 1 win vs. Brewers
The Mets half of the frame was kicked off by Tyrone Taylors one-out double, on which Brewers left fielder Jackson Chourio took a bad route and let it go over his head. Then, after Francisco Alvarez flied out and Francisco Lindor drew a walk, the Mets offense sprang into action.