Jan Alan Alfheim - Hagan, NO Paul Mark Henrichs - Houston TX Eric Paul Hohenschuh - Berwyn PA Edvin Wilheim Johannesen - Oslo, NO William Anthony Sanderson - late of Wayne PA Robert Allen Snow - West Chester PA
Amersham Health AS - Oslo
600407, 601 2, 604 22, 424 91, 600431
A method of treatment of a human or animal body by sonodynamic therapy in which a sensitizer agent is administered to the body and the body is exposed to ultrasound to achieve a cytopathogenic effect at a site therein, wherein the said sensitizer agent is a physiologically tolerable substance which is capable of enhancing the cytopathogenic efficacy of said sonodynamic therapy. Preferably, the sensitizer agent is a water-soluble polymer compound or a conjugate thereof.
Robert Allen Snow - West Chester PA Paul Mark Henrichs - Houston TX Daniel Joseph Delecki - Radnor PA William Anthony Sanderson - late of Wayne PA Vinay Chandrakant Desai - Phoenixville PA Edward Bacon - Audubon PA Kenneth Robert Hollister - Chester Springs PA Eric Paul Hohenschuh - Berwyn PA
Nycomed Imaging AS - Oslo
424 96, 548 3, 548223, 549402, 549427, 549455
This invention provides a physiologically tolerable light imaging contrast agent compound having a molecular weight in the range 500 to 5000000 and containing at least two chromophores having delocalized electron systems as well as at least one polyalkylene oxide (PAO) moiety having a molecular weight in the range 60 to 100000.