Elizabeth Cherry Squiers from 229 Myrtle St, Princeton By The Sea, CA 94019, age 65, Phone: 650 726-6602

Elizabeth Cherry Squiers

Address:

Half Moon Bay, CA 94019

License #:

MD041996L - Expired

Category:

Medicine

Type:

Medical Physician and Surgeon

Dr. Elizabeth Squiers, Half Moon Bay CA - MD (Doctor of Medicine)

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Specialties:

General Surgery

Address:

229 Myrtle St, Half Moon Bay, CA 94019
650 726-6618 (Phone), 650 726-6602 (Fax)

Certifications:

General Surgery, 2009

Awards:

Healthgrades Honor Roll

Languages:

English

Education:

Medical School
Thomas Jefferson University
Graduated: 1983
Medical School
Beaumont Hospital-Royal Oak Campus
Graduated: 1983
Medical School
Shands Hospital At The University Of Florida
Graduated: 1983

Elizabeth Cherry Squiers

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Specialties:

Surgery
Transplant Surgery

Education:

Thomas Jefferson University (1983)

Us Patents

Modulation Of Hsp47 Expression
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US Patent:

20110178157, Jul 21, 2011
Filed:

Dec 8, 2010
Appl. No.:

12/963600
Inventors:

Xiaomei Jin - Oceanside CA, US
Lei Yu - Oceanside CA, US
Hirokazu Takahashi - Sapporo, JP
Yasunobu Tanaka - Sapporo, JP
Yoshiro Niitsu - Sapporo, JP
Elena Feinstein - Rehovot, IL
Sharon Avkin-Nachum - Nes Ziona, IL
Hagar Kalinski - Rishon Le-Zion, IL
Igor Mett - Rehovot, IL
Shai Erlich - Belmont CA, US
Elizabeth C. Squiers - Half Moon Bay CA, US
International Classification:

A61K 31/713
C07H 21/02
A61P 43/00
C07H 21/00
US Classification:

514 44 A, 536 245
Abstract:

Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.

Genotype Specific Methods For Treating Human Subjects Using 4-Methylpyrazole
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US Patent:

20120252857, Oct 4, 2012
Filed:

Jun 9, 2010
Appl. No.:

13/376933
Inventors:

Thomas E. Daley - San Mateo CA, US
Elizabeth C. Squiers - Half Moon Bay CA, US
Kin-Hung Peony Yu - Hillsborough CA, US
International Classification:

A61K 31/415
A61P 25/28
A61P 25/00
A61P 9/10
A61P 25/16
A61P 35/00
A61P 9/12
US Classification:

514406
Abstract:

Provided herein are methods of administering 4-methylpyrazole (4-MP), or physiologically acceptable salts thereof, to subjects of genetic subpopulations expressing specific polymorphisms of the alcohol dehydrogenase and aldehyde dehydrogenase genes. Also provided herein are methods to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with acetaldehyde accumulation accompanying ethanol consumption, or reduce the risk of diseases or disorders caused by consumption of ethanol, comprising administering 4-MP, or physiologically acceptable salts thereof, to subjects of these subpopulations.

Genotype Specific Methods For Treating Human Subjects Using 4-Methylpyrazole
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US Patent:

20120322843, Dec 20, 2012
Filed:

Jun 21, 2012
Appl. No.:

13/529695
Inventors:

Thomas E. Daley - San Mateo CA, US
Elizabeth C. Squiers - Half Moon Bay CA, US
Kin-Hung Peony Yu - Hillsborough CA, US
Assignee:

RAPTOR THERAPEUTICS INC. - Novato CA
International Classification:

A61K 31/415
A61P 1/12
A61P 1/08
US Classification:

514406
Abstract:

Provided herein are methods of administering 4-methylpyrazole (4-MP), or physiologically acceptable salts thereof, to subjects of genetic subpopulations expressing specific polymorphisms of the alcohol dehydrogenase and aldehyde dehydrogenase genes. Also provided herein are methods to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with acetaldehyde accumulation accompanying ethanol consumption, or reduce the risk of diseases or disorders caused by consumption of ethanol, comprising administering 4-MP, or physiologically acceptable salts thereof, to subjects of these subpopulations.

4-Methylpyrazole Formulations For Inhibiting Ethanol Intolerance
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US Patent:

20130150419, Jun 13, 2013
Filed:

Feb 1, 2013
Appl. No.:

13/757329
Inventors:

Raptor Therapeutiacs Inc. - Novato CA, US
Elizabeth C. Squiers - Half Moon Bay CA, US
Kin-Hung Peony Yu - Hillsborough CA, US
Assignee:

Raptor Therapeutiacs Inc. - Novato CA
International Classification:

A61K 31/415
US Classification:

514406
Abstract:

Provided herein are methods, compositions and formulations to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with acetaldehyde accumulation accompanying ethanol consumption, or reduce the risk of diseases or disorders caused by acetaldehyde accumulation, comprising administering 4-MP, or physiologically acceptable salts thereof, to subjects with reduced or absent aldehyde dehydrogenase subtype 2 (ALDH2) activity.

4-Methylpyrazole Formulations For Inhibiting Ethanol Intolerance
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US Patent:

20110053999, Mar 3, 2011
Filed:

Jun 9, 2010
Appl. No.:

12/797594
Inventors:

Thomas E. Daley - San Mateo CA, US
Elizabeth C. Squiers - Half Moon Bay CA, US
Kin-Hung Peony Yu - Hillsborough CA, US
International Classification:

A61K 31/415
A61P 39/00
A61P 1/00
A61P 35/00
A61P 25/28
A61P 9/12
A61P 25/16
US Classification:

514406
Abstract:

Provided herein are methods, compositions and formulations to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with acetaldehyde accumulation accompanying ethanol consumption, or reduce the risk of diseases or disorders caused by acetaldehyde accumulation, comprising administering 4-MP, or physiologically acceptable salts thereof, to subjects with reduced or absent aldehyde dehydrogenase subtype 2 (ALDH2) activity.

Genotype Specific Methods For Treating Human Subjects Using 4-Methylpyrazole
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US Patent:

20180098964, Apr 12, 2018
Filed:

Oct 19, 2017
Appl. No.:

15/788504
Inventors:

- Lake Forest IL, US
Elizabeth C. SQUIERS - Half Moon Bay CA, US
Kin-Hung P. YU - Hillsborough CA, US
International Classification:

A61K 31/415
A61K 9/00
Abstract:

Provided herein are methods of administering 4-methylpyrazole (4-MP), or physiologically acceptable salts thereof, to subjects of geneic subpopulations expressing specific polymorphisms of the alcohol dehydrogenase and aldehyde dehydrogenase genes. Also provided herein are methods to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with acetaldehyde accumulation accompanying ethanol consumption, or reduce the risk of diseases or disorders caused by consumption of ethanol, comprising administering 4-MP, or physiologically acceptable salts thereof, to subjects of these sub-populations.

Genotype Specific Methods For Treating Human Subjects Using 4-Methylpyrazole
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US Patent:

20170007578, Jan 12, 2017
Filed:

Sep 20, 2016
Appl. No.:

15/270842
Inventors:

- Novato CA, US
Elizabeth C. Squiers - Half Moon Bay CA, US
Kin-Hung P. Yu - Hillsborough CA, US
International Classification:

A61K 31/415
A61K 9/00
Abstract:

Provided herein are methods of administering 4-methylpyrazole (4-MP), or physiologically acceptable salts thereof, to subjects of genetic subpopulations expressing specific polymorphisms of the alcohol dehydrogenase and aldehyde dehydro genase genes. Also provided herein are methods to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with acetaldehyde accumulation accompanying ethanol consumption, or reduce the risk of diseases or disorders caused by consumption of ethanol, comprising administering 4-MP, or physiologically acceptable salts thereof, to subjects of these subpopulations.

4-Methylpyrazole Formulations For Inhibiting Ethanol Intolerance
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US Patent:

20160243082, Aug 25, 2016
Filed:

May 2, 2016
Appl. No.:

15/144307
Inventors:

- Novato CA, US
Elizabeth C. Squiers - Half Moon Bay CA, US
Kin-Hung Peony Yu - Hillsborough CA, US
International Classification:

A61K 31/415
Abstract:

Provided herein are methods, compositions and formulations to prevent or ameliorate ethanol intolerance, reduce or ameliorate symptoms associated with acetaldehyde accumulation accompanying ethanol consumption, or reduce the risk of diseases or disorders caused by acetaldehyde accumulation, comprising administering 4-MP, or physiologically acceptable salts thereof, to subjects with reduced or absent aldehyde dehydrogenase subtype 2 (ALDH2) activity.