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Elina R Makino

age ~60

from Winchester, MA

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Also known as:
  • Elma R Makino
  • Elina R Nekrasov
Phone and address:
11 Grant Rd, Winchester, MA 01890
781 729-0698
Connected to:

Elina Makino Phones & Addresses

  • 11 Grant Rd, Winchester, MA 01890 • 781 729-0698
  • Newton, MA
  • Cambridge, MA
  • 11 Grant Rd, Winchester, MA 01890 • 781 424-8214

Work

  • Company:
    Genzyme
    Mar 2009
  • Position:
    Associate director, in vitro biology group, drug and biomaterial r&d

Education

  • School / High School:
    Harvard Medical School
    1995
  • Specialities:
    Ph.D. in Biochemistry

Us Patents

  • Glucosylceramide Synthase Inhibitors

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  • US Patent:
    20210261557, Aug 26, 2021
  • Filed:
    Apr 27, 2021
  • Appl. No.:
    17/242016
  • Inventors:
    - Cambridge MA, US
    Cassandra CELATKA - Hull MA, US
    Seng CHENG - Natick MA, US
    Mary A. CROMWELL - Groton MA, US
    Andrew GOOD - Wallingford CT, US
    Bradford HIRTH - Framingham MA, US
    Katherine JANCSICS - Wilmington MA, US
    John P. LEONARD - Manchester NH, US
    Lingyun LI - Waltham MA, US
    James LILLIE - Wellesley MA, US
    Hanlan LIU - Lexington MA, US
    Elina MAKINO - Winchester MA, US
    John MARSHALL - Hopedale MA, US
    Paul MASON - Natick MA, US
    Markus METZ - Waltham MA, US
    Fazeela MORSHED - Waltham MA, US
    Thomas O'SHEA - Wellesley MA, US
    Ronald SCHEULE - Hopkinton MA, US
    Renato SKERLJ - West Newton MA, US
    Bing WANG - Newton MA, US
    Yibin XIANG - Dracut MA, US
    Zhong ZHAO - Wayland MA, US
  • Assignee:
    GENZYME CORPORATION - Cambridge MA
  • International Classification:
    C07D 487/08
    A61K 31/439
    A61K 31/454
    A61K 38/47
    C07D 453/02
    C07D 453/00
    A61K 31/46
    A61K 31/506
    A61K 31/551
    C07D 455/02
  • Abstract:
    The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.

  • Glucosylceramide Synthase Inhibitors

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  • US Patent:
    20200048266, Feb 13, 2020
  • Filed:
    Aug 15, 2019
  • Appl. No.:
    16/542166
  • Inventors:
    - Cambridge MA, US
    Cassandra CELATKA - Hull MA, US
    Seng CHENG - Natick MA, US
    Mary A. CROMWELL - Groton MA, US
    Andrew GOOD - Wallingford CT, US
    Bradford HIRTH - Framingham MA, US
    Katherine JANCSICS - Wilmington MA, US
    John P. LEONARD - Manchester NH, US
    Lingyun LI - Waltham MA, US
    James LILLIE - Wellesley MA, US
    Hanlan LIU - Lexington MA, US
    Elina MAKINO - Winchester MA, US
    John MARSHALL - Hopedale MA, US
    Paul MASON - Natick MA, US
    Markus METZ - Waltham MA, US
    Fazeela MORSHED - Waltham MA, US
    Thomas O'SHEA - Wellesley MA, US
    Ronald SCHEULE - Hopkinton MA, US
    Renato SKERLJ - West Newton MA, US
    Bing WANG - Newton MA, US
    Yibin XIANG - Dracut MA, US
    Zhong ZHAO - Wayland MA, US
  • International Classification:
    C07D 487/08
    A61K 31/439
    A61K 31/454
    A61K 38/47
    C07D 453/02
    C07D 453/00
    A61K 31/46
    A61K 31/506
    A61K 31/551
    C07D 455/02
  • Abstract:
    The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.

  • Glucosylceramide Synthase Inhibitors

    view source
  • US Patent:
    20180065957, Mar 8, 2018
  • Filed:
    Apr 18, 2017
  • Appl. No.:
    15/490385
  • Inventors:
    - Cambrdige MA, US
    Cassandra CELATKA - Hull MA, US
    Seng H. CHENG - Natick MA, US
    Bradford Hirth - Littleton MA, US
    Andrew GOOD - Wallingford CT, US
    Katherine JANCSICS - Wilmington MA, US
    John MARSHALL - Charlestown MA, US
    Markus Metz - Encinitas CA, US
    Ronald K. SCHEULE - Hopkinton MA, US
    Renato SKERLJ - W. Newton MA, US
    Yibin XIANG - Dracut MA, US
    Zhong ZHAO - Wayland MA, US
    John LEONARD - Manchester NH, US
    Thomas NATOLI - Revere MA, US
    Elina MAKINO - Winchester MA, US
    Herve HUSSON - Boston MA, US
    Oxana BESKROVNAYA - Southborough MA, US
  • Assignee:
    Genzyme Corporation - Cambrdige MA
  • International Classification:
    C07D 453/02
    C07D 471/08
    A61K 45/06
    A61K 31/551
    A61K 31/55
    A61K 31/496
    A61K 31/497
    A61K 31/506
    A61K 31/5377
    A61K 31/439
  • Abstract:
    The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.

  • Glucosylceramide Synthase Inhibitors

    view source
  • US Patent:
    20160207933, Jul 21, 2016
  • Filed:
    Aug 25, 2015
  • Appl. No.:
    14/835402
  • Inventors:
    - Cambridge MA, US
    Cassandra CELATKA - Hull MA, US
    Seng CHENG - Natick MA, US
    Mary A. CROMWELL - Groton MA, US
    Andrew GOOD - Wallingford CT, US
    Bradford HIRTH - Framingham MA, US
    Katherine JANCSICS - Wilmington MA, US
    John P. LEONARD - Manchester NH, US
    Lingyun LI - Waltham MA, US
    James LILLIE - Wellesley MA, US
    Hanlan LIU - Lexington MA, US
    Elina MAKINO - Winchester MA, US
    John MARSHALL - Hopedale MA, US
    Paul MASON - Natick MA, US
    Markus METZ - Waltham MA, US
    Fazeela MORSHED - Waltham MA, US
    Thomas O'SHEA - Wellesley MA, US
    Ronald SCHEULE - Hopkinton MA, US
    Renato SKERLJ - West Newton MA, US
    Bing WANG - Newton MA, US
    Yibin XIANG - Dracut MA, US
    Zhong ZHAO - Wayland MA, US
  • International Classification:
    C07D 487/08
    A61K 31/439
    A61K 38/47
    A61K 31/551
    C07D 455/02
    A61K 31/46
    C07D 453/02
    A61K 31/506
  • Abstract:
    The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.

  • Glucosylceramide Synthase Inhibitors

    view source
  • US Patent:
    20150210681, Jul 30, 2015
  • Filed:
    Sep 10, 2013
  • Appl. No.:
    14/427275
  • Inventors:
    - Cambridge MA, US
    Cassandra Celatka - Chesterfield MA, US
    Seng H. Cheng - Wellesley MA, US
    Bradford Hirth - Littleton MA, US
    Andrew Good - Wallingford CT, US
    Katherine Jancsics - Wilmington MA, US
    John Marshall - Hopedale MA, US
    Markus Metz - Waltham MA, US
    Ronald K. Scheule - Hopkinton MA, US
    Renato Skerlj - Newton MA, US
    Yibin Xiang - Dracut MA, US
    Zhong Zhao - Wayland MA, US
    John Leonard - Bridgewater NJ, US
    Thomas Natoli - Southborough MA, US
    Elina Makino - Winchester MA, US
    Herve Husson - Boston MA, US
    Oxana Beskrovnaya - Southborough MA, US
  • Assignee:
    GENZYME CORPORATION - Cambrdige MA
  • International Classification:
    C07D 453/02
    C07D 471/08
    A61K 31/55
    A61K 45/06
    A61K 31/506
    A61K 31/497
    A61K 31/439
    A61K 31/5377
    A61K 31/496
    A61K 31/551
  • Abstract:
    The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.

Resumes

Elina Makino Photo 1

Senior Director, Rare Disease

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Location:
11 Grant Rd, Winchester, MA 01890
Industry:
Research
Work:
Sigilon Therapeutics, Inc.
Senior Director, Rare Disease
Sanofi Jun 2007 - Aug 2018
Scientific Director
Sanofi Genzyme Jun 2007 - Aug 2018
Scientific Director
Sanofi Genzyme Jun 2007 - Mar 2014
Associate Director
Emd Millipore Jan 2006 - May 2007
Senior Scientist
Education:
Weizmann Institute of Science 1990 - 1995
Doctorates, Doctor of Philosophy, Biochemistry, Philosophy Moscow State University
Skills:
Drug Discovery
Biochemistry
Assay Development
Biotechnology
High Throughput Screening
Cell
Drug Development
Life Sciences
Oncology
Cell Culture
Neuroscience
In Vitro
Pharmaceutical Industry
Molecular Biology
Immunology
Molecular and Cellular Biology
Cell Biology
Lifesciences
Biopharmaceuticals
Technology Transfer
Genomics
Elisa
Dna
Protein Chemistry
Purification
Pcr
Genetics
Rare Diseases
Opthalmology
Clinical Biomarkers
Rare Disease
Elina Makino Photo 2

Sr Scientist At Genzyme

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Location:
Greater Boston Area
Industry:
Pharmaceuticals
Elina Makino Photo 3

Elina Makino Winchester, MA

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Work:
Genzyme

Mar 2009 to 2000
Associate Director, In Vitro Biology Group, Drug and Biomaterial R&D Millipore Corporation

Jan 2006 to May 2007
Senior Research Scientist I, Technology Development Group Elina Makino
Cambridge, MA
May 2005 to Nov 2005
Senior Scientist I, Assay Development, Cell Biology Scientist II, Assay Development, cell biology
May 2000 to May 2005 Department of Ophthalmology, Harvard Medical School
Boston, MA
Dec 1995 to Apr 2000
Postdoctoral Fellow Elina Makino

1990 to 1995
Predoctoral Fellow A.N. Belozersky, Laboratory of Molecular Biology and Bioorganic Chemistry

1988 to 1990
Junior Research Scientist
Education:
Harvard Medical School
1995 to 2000
Ph.D. in Biochemistry Weizmann Institute of Science
M.S. in Biochemistry

Youtube

Nik Makino ft. Flow G performs Moon LIVE on W...

Nik Makino ft. Flow G performs Moon LIVE on Wish 1...

Hip-hop acts Nik Makino and Flow G perform "Moon" live on the Wish 107...

  • Duration:
    3m 57s

Amelia, Avelina & Akim and the story about sc...

Amelia, Avelina & Akim and the story about school ...

Avelina and Akim are at school when a new bully joins the class. Aveli...

  • Duration:
    4m 2s

Nik Makino - LEXI

Nik Makino - LEXI

S U B S C R I B E N O W ! ! ! FB/ IG @

  • Duration:
    3m 50s

How to loom

How to loom
  • Duration:
    5m 26s

Nik Makino - LEXI (Official Music Video)

Nik Makino - LEXI (Official Music Video)

LEXI #LEXI Nik Makino - LEXI (Official Music Video) OUT NOW! Produced ...

  • Duration:
    4m 27s

Presentation: "The Makino Collection at Colum...

Presentation: "The Makino Collection at Columbia: ...

Beth Katzoff is Archival/Public Services Librarian, The Makino Mamoru ...

  • Duration:
    17m 3s

Elina finds a new Black Mesa Displacer Cannon...

Elina finds a new Black Mesa Displacer Cannon #sho...

Art account: ...

  • Duration:
    9s

We talk about young children how to take care...

We talk about young children how to take care!!!

... mm - I'm Elina owner you know teenager wrote Makino at this McKenn...

  • Duration:
    1h 2m 30s

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Elina Makino

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