Edwin Y Wang

US Patent:

6520934, Feb 18, 2003

Filed:

Dec 29, 1999

Appl. No.:

09/474668

Inventors:

Jeong S. Lee - Diamond Bar CA
Vidya Nayak - Cupertino CA
John Schreiner - Hemet CA
Christine Gutting - Murrieta CA
Edwin Wang - Tustin CA
Gary Heinemann - Campbell CA
Roseminda White - Wildomar CA

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61M 2900

US Classification:

6041031

Abstract:

A catheter assembly comprising a shaft and at least one flexible radiopaque marker affixed with the shaft. Flexibility of radiopaque marker is achieved by using a segmented band of radiopaque material or a coiled band formed by winding a wire or hollow tube filled with radiopaque material. The flexible radiopaque marker may be affixed with the shaft by an adhesive, by swaging, by crimping, by soldering, or by spring-action tension fit against the shaft.

US Patent:

6863678, Mar 8, 2005

Filed:

Sep 19, 2001

Appl. No.:

09/957526

Inventors:

Jeong S. Lee - Diamond Bar CA, US
Edwin Wang - Tustin CA, US
Roseminda J. White - Wildomar CA, US

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61M029/00

US Classification:

606192, 606194, 60410309, 604 9601

Abstract:

A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400 C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.

US Patent:

6911017, Jun 28, 2005

Filed:

Sep 19, 2001

Appl. No.:

09/957354

Inventors:

Jeong S. Lee - Diamond Bar CA, US
Edwin Wang - Tustin CA, US
Roseminda J. White - Wildomar CA, US
Jose A. Romero - Perris CA, US

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61M029/00

US Classification:

604 9601, 606194

Abstract:

Medical devices or components thereof, and particularly intracorporeal devices for therapeutic or diagnostic uses, which are formed at least in part of a polymeric material and a ferromagnetic or paramagnetic material, so that the medical device or component thereof is visible on magnetic resonance imaging (MRI) scans. In one embodiment, the medical device is a balloon catheter having an MRI visible balloon. In a presently preferred embodiment, there is an insufficient amount of the ferromagnetic or paramagnetic material within a wall of the balloon or coated onto a wall of the balloon to make the balloon radiopaque.

US Patent:

6918920, Jul 19, 2005

Filed:

Nov 1, 2001

Appl. No.:

10/002613

Inventors:

Edwin Wang - Tustin CA, US
Roseminda J. White - Wildomar CA, US
Jeong S. Lee - Temecula CA, US
Tim Kitchen - Sunnyvale CA, US

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61M029/00

US Classification:

606194

Abstract:

An elongated balloon catheter having a distal tip member on the distal end of the catheter having a sleeve surrounding and secured at least to the proximal end of the distal tip member.

US Patent:

6939321, Sep 6, 2005

Filed:

Sep 26, 2002

Appl. No.:

10/255487

Inventors:

Edwin Wang - Tustin CA, US
Florencia Lim - Union City CA, US
Huong Chung - San Jose CA, US
Chi Le Long - San Jose CA, US
Nadine Ding - San Jose CA, US

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61M031/00
A61M037/00
A61M029/00
A61F002/06

US Classification:

60410308, 604103, 60410305, 606194, 623 111

Abstract:

A balloon catheter and a method of making the balloon catheter, having a balloon which is bonded to an elongated shaft, and which has a first layer and a second layer and an improved strong bond between the balloon and the shaft. One aspect of the invention is directed to a balloon in which the balloon first layer has at least a section with a gas plasma-etched or chemical solution-etched surface for improved bondability. Another aspect of the invention is directed to a balloon in which the balloon first layer has a proximal end section bonded to an outer surface of the shaft and the balloon second layer has a proximal end section bonded to an inner surface of the shaft, and, in one embodiment, at least a section of the balloon first layer has a gas plasma-etched or chemical solution-etched surface.

US Patent:

6946173, Sep 20, 2005

Filed:

Mar 21, 2002

Appl. No.:

10/103274

Inventors:

Florencia Lim - Union City CA, US
Chi Le Long - San Jose CA, US
Charles D. Claude - Santa Clara CA, US
Jeong S. Lee - Diamond Bar CA, US
Srinivasan Sridharan - Morgan Hill CA, US
Fernando Gonzalez - Campbell CA, US
Edwin Wang - Tustin CA, US

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

B32B001/08
A61M025/10
A61M029/00

US Classification:

428 352, 428 341, 428 357, 428 365, 428 368, 428 369, 428 3691, 604 9601, 60410305, 60410306, 60410308, 60410311, 60410313, 604264, 604523

Abstract:

A catheter balloon formed of a polymeric material such as expanded polytetrafluoroethylene (ePTFE) bonded to a second layer formed of a low tensile set polymer and/or impregnated with a low tensile set polymer. In a presently preferred embodiment, the low tensile set polymer is a silicone-polyurethane copolymer elastomer or a diene polymer elastomer. The low tensile set polymer has high strength, low modulus, high elongation, and low tensile set. The diene or silicone-polyurethane has a low tensile set, which facilitates deflation of the balloon to a low profile deflated configuration. One aspect of the invention provides improved attachment of the diene to the ePTFE. In one embodiment, the second layer is formed of a diene mixed with a bonding promoter such as a vulcanizing agent which is covalently bonded to the diene.

US Patent:

6979342, Dec 27, 2005

Filed:

Sep 19, 2001

Appl. No.:

09/957593

Inventors:

Jeong S. Lee - Diamond Bar CA, US
Edwin Wang - Tustin CA, US

Assignee:

Advanced Cardiovascular Systems, INCC - Santa Clara CA

International Classification:

A61M029/00

US Classification:

606192, 604 9601

Abstract:

A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.

US Patent:

7147619, Dec 12, 2006

Filed:

Jul 22, 2002

Appl. No.:

10/200274

Inventors:

Florencia Lim - Union City CA, US
Jeong S. Lee - Diamond Bar CA, US
Edwin Wang - Tustin CA, US

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61M 29/02

US Classification:

60410306, 604103, 604 9601, 606194

Abstract:

A balloon catheter and a method of making a balloon catheter, having a balloon with a first layer and a second layer, the first layer having at least one impregnated section impregnated with a polymeric material compatible with a polymeric material forming the catheter shaft. At least a portion of the impregnated section is fusion bonded to the shaft. In a presently preferred embodiment, the impregnated section is adjacent to a section of the first layer which is not impregnated with the compatible polymeric material. The impregnated section provides improved bonding of the balloon to the catheter shaft while minimizing the effect of the bond on catheter performance characteristics such as profile and flexibility.