Edward T Kopesky from 295 Wildridge Rd, Saint Paul, MN 55115, age 46

Methods For Making Oxidation-Resistant Cross-Linked Polymeric Materials
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US Patent:

8293811, Oct 23, 2012
Filed:

Jan 25, 2008
Appl. No.:

12/522728
Inventors:

Orthun K. Muratoglu - Cambridge MA, US
Edward T. Kopesky - Arlington MA, US
Ebru Oral - Newton MA, US
Assignee:

The General Hospital Corporation - Boston MA
Cambridge Polymer Group, Inc. - Boston MA
International Classification:

C08F 2/46
C08J 3/28
A61F 2/02
A61F 2/30
A61L 27/50
A61L 27/16
C08L 23/06
C08K 5/1545
US Classification:

522161, 522 75, 522 79, 522 80, 522 74, 522 71, 522157, 522150, 522158, 522111, 522112, 523113, 523115, 523300, 524100, 524585, 524587, 623 1111
Abstract:

The present invention relates to methods for making cross-linked oxidation-resistant polymeric materials and preventing or minimizing in vivo elution of antioxidant from the antioxidant-containing polymeric materials. The invention also provides methods of doping polymeric materials with a spatial control of cross-linking and antioxidant distribution, for example, vitamin E (α-Tocopherol), and methods for extraction/elution of antioxidants, for example, vitamin E (α-tocopherol), from surface regions of antioxidant-containing polymeric materials, and materials used therewith also are provided.

Sealing Elements And Sealing Element Compositions
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US Patent:

8552117, Oct 8, 2013
Filed:

Jun 13, 2012
Appl. No.:

13/495503
Inventors:

Kevin G. Cai - Cumberland RI, US
Edward T. Kopesky - Arlington MA, US
Assignee:

Teknor Apex Company - Pawtucket RI
International Classification:

C08L 23/08
US Classification:

525236, 525240, 525241, 525274, 525296, 525553, 525577, 5263486, 526347
Abstract:

Polyolefin based sealing element compositions with good oxygen barrier properties particularly suitable for forming sealing elements, for example gaskets and cap liners that are especially useful for sealing containers having products such as liquids or food-stuffs therein. The compositions when formed as sealing elements do not appreciably contribute taste and/or odor to a packaged product including the sealing element. The compositions have desirable rheological properties and are thus readily processable at various temperatures.

Methods For Making Oxidation-Resistant Cross-Linked Polymeric Materials
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US Patent:

8569395, Oct 29, 2013
Filed:

Jul 31, 2012
Appl. No.:

13/562867
Inventors:

Orhun K. Muratoglu - Cambridge MA, US
Edward T. Kopesky - Arlington MA, US
Ebru Oral - Newton MA, US
Assignee:

The General Hospital Corporation - Boston MA
Cambridge Polymer Group, Inc. - Boston MA
International Classification:

C08F 2/46
C08J 3/28
A61F 2/02
A61F 2/30
A61L 27/50
A61L 27/16
C08L 23/06
C08K 5/1545
US Classification:

522161, 522 75, 522 79, 522 80, 522 74, 522 71, 522150, 522158, 522111, 523113, 523115, 523300, 524100, 524585, 524587, 623 1111
Abstract:

The present invention relates to methods for making cross-linked oxidation-resistant polymeric materials and preventing or minimizing in vivo elution of antioxidant from the antioxidant-containing polymeric materials. The invention also provides methods of doping polymeric materials with a spatial control of cross-linking and antioxidant distribution, for example, vitamin E (α-Tocopherol), and methods for extraction/elution of antioxidants, for example, vitamin E (α-tocopherol), from surface regions of antioxidant-containing polymeric materials, and materials used therewith also are provided.

Hydrolyzed Hydrogels
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US Patent:

8637063, Jan 28, 2014
Filed:

Dec 7, 2009
Appl. No.:

13/132507
Inventors:

Edward T. Kopesky - Arlington MA, US
Jason Berlin - Everett MA, US
Martin F. Van Buren - Chelmsford MA, US
Gavin J. C. Braithwaite - Cambridge MA, US
Assignee:

Cambridge Polymer Group, Inc. - Boston MA
International Classification:

A61F 13/00
A61K 31/74
A61F 2/02
A61F 2/28
US Classification:

424422, 424 7808, 524916, 623 1111, 623 1611, 623 2358
Abstract:

The invention provides methods of making hydrolyzed cross-linked polyvinyl alcohol (PVA) hydrogels by polymerizing vinyl acetate (VAc) monomers to polyvinyl acetate (PVAc) polymer network by chemical-crosslinking and hydrolysis. The invention also provides methods for including pendant chains in the hydrogel during the polymerization process. Materials produced and use of the cross-linked hydrolyzed PVA hydrogels also are disclosed herein.

Left Atrial Appendage Closure Device With Anti-Thrombogenic Covering
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US Patent:

20230052812, Feb 16, 2023
Filed:

Oct 14, 2022
Appl. No.:

17/966598
Inventors:

- MAPLE GROVE MN, US
EDWARD KOPESKY - MAHTOMEDI MN, US
Assignee:

BOSTON SCIENTIFIC SCIMED, INC. - MAPLE GROVE MN
International Classification:

A61B 17/12
Abstract:

Medical devices as wells as methods for making and using medical devices are disclosed. An example medical device may include a left atrial appendage device. The left atrial appendage device may include an expandable frame configured to shift between a first configuration and an expanded configuration. A fabric mesh may be disposed along at least a portion of the expandable frame. An anti-thrombogenic coating may be disposed along the fabric mesh.

Direct Oral Anticoagulant-Eluting Medical Device
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US Patent:

20230011767, Jan 12, 2023
Filed:

Jul 8, 2022
Appl. No.:

17/860848
Inventors:

- Maple Grove MN, US
Edward Kopesky - Mahtomedi MN, US
Assignee:

BOSTON SCIENTIFIC SCIMED, INC. - MAPLE GROVE MN
International Classification:

A61B 17/12
A61K 31/4545
A61K 31/5377
A61K 31/444
Abstract:

A device for permanent placement across an atrial appendage ostium in a patient includes a support structure having a contracted delivery configuration and an expanded deployed configuration defining a radially enlarged portion to permanently engage an interior wall of the atrial appendage, a membrane attached to the support structure and configured to extend across the ostium of the atrial appendage when the support structure is in the expanded deployed configuration, and a polymer coating disposed on at least one of the support structure and the membrane, the polymer coating including a direct oral anticoagulant (DOAC) dispersed in a polymer.

Methods For Making Oxidation-Resistant Cross-Linked Polymeric Materials
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US Patent:

20170049934, Feb 23, 2017
Filed:

Jun 24, 2016
Appl. No.:

15/191857
Inventors:

Orhun K. MURATOGLU - Cambridge MA, US
Edward T. KOPESKY - Acton MA, US
Ebru ORAL - Newton MA, US
Assignee:

The General Hospital Corporation - Boston MA
Cambridge Polymer Group, Inc. - Boston MA
International Classification:

A61L 27/50
C08K 5/1545
B29C 43/18
C08J 3/28
B29C 43/00
A61L 27/16
C08J 3/24
Abstract:

The present invention relates to methods for making cross-linked oxidation-resistant polymeric materials and preventing or minimizing in vivo elution of antioxidant from the antioxidant-containing polymeric materials. The invention also provides methods of doping polymeric materials with a spatial control of cross-linking and antioxidant distribution, for example, vitamin E (α-Tocopherol), and methods for extraction/elution of antioxidants, for example, vitamin E (α-tocopherol), from surface regions of antioxidant-containing polymeric materials, and materials used therewith also are provided.