Donald L King

US Patent:

48164046, Mar 28, 1989

Filed:

Feb 18, 1986

Appl. No.:

6/830697

Inventors:

Nicole Suciu-Foca - Cliffside Park NJ
Donald W. King - Chicago IL

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12N 500
C07K 1504

US Classification:

43524027

Abstract:

Late differentiation antigens (LDA. sub. 1 and LDA. sub. 2) expressed by activated helper cells are described. LDA. sub. 1 and LDA. sub. 2 are membrane proteins recognized by monoclonal antibodies produced by immunizing mice with alloreactive human T cell clones with helper function. LDA. sub. 1 and LDA. sub. 2 are expressed by helper T cells. LDA. sub. 1 monoclonal antibody and LDA. sub. 2 monoclonal antibody block T cell enhancement of B cell immunoglobulin production. Thus, LDA. sub. 1 and LDA. sub. 2 are associated with helper T cell effector function. Methods of diagnosis and therepy based upon LDA. sub. 1 and LDA. sub. 2 are also described.

US Patent:

50665812, Nov 19, 1991

Filed:

Feb 5, 1987

Appl. No.:

7/011004

Inventors:

Nicole Suciu-Foca - Cliffside Park NJ
Donald W. King - Chicago IL

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C07K 1506
C07K 1528
G01N 33567
G01N 33577

US Classification:

435 724

Abstract:

This invention provides a purified new differentiation antigen, designated NDA. sub. 3, associated with the growth and proliferation of activated B lymphocytes and characterized by a molecular weight of about 36,000 daltons. The invention also provides an antibody capable of specifically forming a complex with purified NDA. sub. 3. Another aspect of the invention provides a hybridoma which produces a monoclonal antibody that specifically recognizes the isolated NDA. sub. 3. The invention also pertains to a method for detecting B cells or helper T cells, each of which has a B cell growth factor receptor, which comprises contacting a sample which contains B cells or helper T cells with substances capable of forming complexes with the B cell growth factor receptors so as to form cellular complexes between the substances and the B cell growth factor receptors, and detecting such cellular complexes.

US Patent:

54057507, Apr 11, 1995

Filed:

Jun 2, 1992

Appl. No.:

7/893596

Inventors:

Nicole Suciu-Foca - Cliffside Park NJ
Donald W. King - Chicago IL

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C07K 1528
G01N 33577

US Classification:

435724

Abstract:

This invention provides a purified new differentiation antigen, designated NDA4, associated with the growth and proliferation of activated B lymphocytes and characterized by a molecular weight of about 46,000 daltons. The invention also provides an antibody capable of specifically forming a complex with purified NDA4, and a hybridoma which produces a monoclonal antibody that specifically recognizes the isolated NDA4. The invention also pertains to a method for dectecting B cells or helper T cells, each of which has a B cell growth factor receptor, which comprises contacting a sample which contains B cells or helper T cells with substances capable of forming complexes with the B cell growth factor receptors so as to form cellular complexes between the substances and the B cell growth factor receptors, and detecting such cellular complexes.

US Patent:

48186899, Apr 4, 1989

Filed:

Jul 5, 1985

Appl. No.:

6/752397

Inventors:

Nicole Suciu-Foca - Cliffside Park NJ
Donald W. King - Chicago IL

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

G01N 3353

US Classification:

435 7

Abstract:

A late differentiation antigen (LDA. sub. 1) expressed by activated helper cells is described. LDA. sub. 1 is a membrane protein recognized by a monoclonal antibody produced by immunizing mice with an alloreactive human T cell clone with helper function. LDA. sub. 1 is expressed by helper T cells optionally 9 days after activation. Anti-LDA. sub. 1 monoclonal antibody blocks T cell enhancement of B-cell immunoglobulin production. Thus, LDA. sub. 1 is associated with helper T cell effector function. Methods of diagnosis and therapy based upon LDA. sub. 1 are also described.

US Patent:

RE303976, Sep 9, 1980

Filed:

Apr 2, 1979

Appl. No.:

6/026088

Inventors:

Donald L. King - Darien CT

International Classification:

A61B 1000

US Classification:

128660

Abstract:

An apparatus for collecting three-dimensional data on the size, shape, location and nature of animal soft tissue organ structures within the animal and reconstructing the data outside the animal. The apparatus provides a representation of the size, shape, location and nature of the structure in three dimensions.

US Patent:

41009169, Jul 18, 1978

Filed:

Apr 27, 1976

Appl. No.:

5/680885

Inventors:

Donald L. King - Darien CT

International Classification:

A61B 1000

US Classification:

128 2V

Abstract:

An apparatus for collecting three-dimensional data on the size, shape, location and nature of animal soft tissue organ structures within the animal and reconstructing the data outside the animal. The apparatus provides a representation of the size, shape, location and nature of the structure in three dimensions.

Author:

Donald King

ISBN #:

0571133711

Author:

Donald King

ISBN #:

0595357679

Author:

Donald King

ISBN #:

0728703629

Author:

Donald King

ISBN #:

0916896374

Author:

Donald C. King

ISBN #:

0786419105

Author:

Donald L. King

ISBN #:

0470263865

Author:

Donald L. King

ISBN #:

0898760674

Author:

Donald B. King

ISBN #:

0137426100

Address:

3217 E 4 St, Dayton, OH 45403

Phone:

937 258-2163

VIN:

1G1ZD5EU5CF292114

Make:

CHEVROLET

Model:

MALIBU

Year:

2012

Address:

4515 Douglas Ave, Bronx, NY 10471

Phone:

718 543-4635

VIN:

JTHBK1EG5B2459027

Make:

LEXUS

Model:

ES 350

Year:

2011

Address:

3723 Medford Rd, Durham, NC 27705

VIN:

1GNFK13027J402765

Make:

CHEVROLET

Model:

TAHOE

Year:

2007

Address:

102 Milford Ln, Durham, NC 27713

Phone:

919 382-8054

VIN:

1GCJK33D37F191287

Make:

CHEVROLET

Model:

SILVERADO

Year:

2007