David M Goodlett

Author:

David Eugene Goodlett

ISBN #:

0773453989

US Patent:

20210080458, Mar 18, 2021

Filed:

Nov 23, 2020

Appl. No.:

17/101693

Inventors:

- Turun yliopisto, FI
Santosh BHOSALE - Turku, FI
David GOODLETT - Baltimore MD, US
Harri LÄHDESMÄKI - Espoo, FI
Olli SIMELL - Raisio, FI
Riitta LAHESMAA - Turku, FI

Assignee:

TURUN YLIOPISTO - Turun yliopisto

International Classification:

G01N 33/564
G01N 33/92

Abstract:

The present invention relates to methods for predicting a risk of a subject for Type 1 diabetes (T1D) on the basis of expression levels of protein markers in a sample obtained from the subject. The present invention also relates to in vitro kits for use in said methods.

US Patent:

20170211012, Jul 27, 2017

Filed:

Feb 17, 2015

Appl. No.:

15/118338

Inventors:

- Baltimore MD, US
David GOODLETT - Baltimore MD, US
Daniel POWELL - Oro Valley AZ, US

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

C11B 1/10
C11B 1/02

Abstract:

Improved methods for extracting lipid-containing molecules from microbes are disclosed. The methods utilize selected surfactants for extraction of lipids and lipopolysaccharides from microbes, such as bacteria and fungi. The extracted lipids and lipopolysaccharides may be used, for example, to identify the source microbe via mass spectroscopy.

US Patent:

20170211120, Jul 27, 2017

Filed:

Jan 20, 2017

Appl. No.:

15/410948

Inventors:

Robert K. Ernst - Silver Spring MD, US
David Goodlett - Baltimore MD, US
Lisa Leung - Laurel MD, US

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

C12Q 1/04
H01J 49/00
G01N 33/92
G01N 27/62
C12Q 1/18
G01N 33/49

Abstract:

Provided herein are methods for rapidly identifying a microbe, such as a pathogen, from a biological sample including, blood, urine, wound effluent, stool, serum, and bronchoalveolar lavage fluid. The method comprises obtaining the sample from the subject and performing a spectrometric analysis of the lipids in the microbe to obtain a profile. The profile obtained is compared with a molecular mass lipid profile of known microbes for identification. Also provided is a method for identifying one or more antimicrobial drugs effective to treat a microbial strain in a subject.

US Patent:

20170160276, Jun 8, 2017

Filed:

Jun 18, 2015

Appl. No.:

15/319515

Inventors:

- Turun yliopisto, FI
Santosh BHOSALE - Turku, FI
David GOODLETT - Baltimore MD, US
Harri LÄHDESMÄKI - Espoo, FI
Olli SIMELL - Raisio, FI
Riitta LAHESMAA - Turku, FI

Assignee:

TURUN YLIOPISTO - Turun yliopisto

International Classification:

G01N 33/564
G01N 33/92

Abstract:

The present invention relates to methods for predicting a risk of a subject for Type 1 diabetes (T1D) on the basis of expression levels of protein markers in a sample obtained from the subject. The present invention also relates to in vitro kits for use in said methods.