Gwynedd A. Benders - Portland OR, US John I. Glass - Germantown MD, US Carole Lartigue - Des Arenes Bayonne, FR Sanjay Vashee - Boyds MD, US Mikkel A. Algire - Jessup MD, US Hamilton O. Smith - San Diego CA, US Charles E. Merryman - Sykesville MD, US Vladimir N. Noskov - Montgomery Village MD, US Ray-Yuan Chuang - Rockville MD, US Daniel G. Gibson - Crofton MD, US J. Craig Venter - La Jolla CA, US
Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.
Gwynedd A. Benders - Portland OR, US John I. Glass - Germantown MD, US Clyde A. Hutchison - La Jolla CA, US Carole Lartigue - Des Arenes Bayonne, FR Sanjay Vashee - Boyds MD, US Mikkel A. Algire - Jessup MD, US Hamilton O. Smith - San Diego CA, US Charles E. Merryman - Sykesville MD, US Vladimir N. Noskov - Montgomery Village MD, US Ray-Yuan Chuang - Rockville MD, US Daniel G. Gibson - Crofton MD, US J. Craig Venter - La Jolla CA, US
Assignee:
Synthetic Genomics, Inc. - La Jolla CA
International Classification:
C12N 15/87 C12N 1/21
US Classification:
435455, 435471, 435468, 4352523
Abstract:
Compositions and methods are disclosed herein for cloning a synthetic or a semi-synthetic donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.
Capital Region Medical ClinicCapital Region Health Branch West 3308 W Edgewood Dr STE B, Jefferson City, MO 65109 573 893-7848 (phone), 573 893-1984 (fax)
Capital Region Medical ClinicCapital Region Physicians Urgent Care 220 Madison St, Jefferson City, MO 65101 573 632-4900 (phone), 573 644-6650 (fax)
Education:
Medical School Oklahoma State University Center for Health Sciences College of Osteopathic Medicine Graduated: 1999
Procedures:
Allergen Immunotherapy Electrocardiogram (EKG or ECG) Vaccine Administration Wound Care
Dr. Gibson graduated from the Oklahoma State University Center for Health Sciences College of Osteopathic Medicine in 1999. He works in Jefferson City, MO and 1 other location and specializes in Family Medicine and Urgent Care Medicine. Dr. Gibson is affiliated with Capital Region Medical Center.