Daniel J Gibson

Author:

Daniel Gibson

ISBN #:

0312207778

US Patent:

20110053272, Mar 3, 2011

Filed:

Mar 5, 2010

Appl. No.:

12/718911

Inventors:

Gwynedd A. Benders - Portland OR, US
John I. Glass - Germantown MD, US
Carole Lartigue - Des Arenes Bayonne, FR
Sanjay Vashee - Boyds MD, US
Mikkel A. Algire - Jessup MD, US
Hamilton O. Smith - San Diego CA, US
Charles E. Merryman - Sykesville MD, US
Vladimir N. Noskov - Montgomery Village MD, US
Ray-Yuan Chuang - Rockville MD, US
Daniel G. Gibson - Crofton MD, US
J. Craig Venter - La Jolla CA, US

International Classification:

C12N 15/74
C12N 15/82
C12N 15/85
C12N 1/21
C12N 1/15
C12N 1/19
C12N 5/10

US Classification:

435455, 435471, 435468, 4352523, 43525411, 4352542, 435419, 435348, 435325

Abstract:

Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.

US Patent:

20110053273, Mar 3, 2011

Filed:

May 19, 2010

Appl. No.:

12/783489

Inventors:

Gwynedd A. Benders - Portland OR, US
John I. Glass - Germantown MD, US
Clyde A. Hutchison - La Jolla CA, US
Carole Lartigue - Des Arenes Bayonne, FR
Sanjay Vashee - Boyds MD, US
Mikkel A. Algire - Jessup MD, US
Hamilton O. Smith - San Diego CA, US
Charles E. Merryman - Sykesville MD, US
Vladimir N. Noskov - Montgomery Village MD, US
Ray-Yuan Chuang - Rockville MD, US
Daniel G. Gibson - Crofton MD, US
J. Craig Venter - La Jolla CA, US

Assignee:

Synthetic Genomics, Inc. - La Jolla CA

International Classification:

C12N 15/87
C12N 1/21

US Classification:

435455, 435471, 435468, 4352523

Abstract:

Compositions and methods are disclosed herein for cloning a synthetic or a semi-synthetic donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.