The present invention relates to methods of tissue grafting and microvascular free flap transfer that involve administering a phosphodiesterase type-5 inhibitor to the tissue graft or microvascular free flap to produce a treated graft or flap, and implanting the treated graft or flap into a recipient site of a host subject.
Manipulating Stem-Progenitor Cell Trafficking To Injured Tissue And/Or Tumors By Altering Hif-1 And/Or Sdf-1 Activity
Daniel Ceradini - New York NY, US Geoffrey Gurtner - New York NY, US
International Classification:
A61K 48/00 A61K 38/18
US Classification:
514012000, 514044000
Abstract:
The present invention relates to a method for modulating recruitment of stem cells or progenitor cells to a selected tissue site. Methods for treating damaged tissue and for treating cancerous tumor tissue are also disclosed. These methods involve regulating HIF-1 and/or SDF-1 activity in the tissue.
Medicine Doctors
Dr. Daniel J Ceradini, New York NY - MD (Doctor of Medicine)
New York University Institute Reconstructive Plastic Surgery 307 E 33 St Lowr Level, New York, NY 10016 212 263-5834 (phone), 212 263-5400 (fax)
Education:
Medical School New York University School of Medicine Graduated: 2000
Procedures:
Breast Reconstruction Breast Reduction Hernia Repair
Conditions:
Breast Disorders Gastrointestinal Hemorrhage Malignant Neoplasm of Female Breast Melanoma Overweight and Obesity
Languages:
English Spanish
Description:
Dr. Ceradini graduated from the New York University School of Medicine in 2000. He works in New York, NY and specializes in Plastic Surgery. Dr. Ceradini is affiliated with NYU Langone Medical Center.
Daniel Ceradini, New York NY
Work:
Manhattan Campus of the VA NY Harbor Healthcare System
423 E 23Rd St, New York, NY 10010
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