Daniel E Aultz from Branchburg, NJ

Process For Preparing Heteroarylbenzoxepin-Acetic Acids, Precursors And Derivatives Thereof
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US Patent:

41071778, Aug 15, 1978
Filed:

Apr 19, 1977
Appl. No.:

5/788958
Inventors:

Arthur Raymond McFadden - East Brunswick NJ
Daniel Eugene Aultz - Middlesex NJ
Assignee:

American Hoechst Corporation - Bridgewater NJ
International Classification:

C07D33324
US Classification:

2603322C
Abstract:

Heteroarylbenzoxepin-acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and processes for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.

Precursors Of Heterothienobenzoxepin Acetic Acids
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US Patent:

40814572, Mar 28, 1978
Filed:

Apr 19, 1977
Appl. No.:

5/788753
Inventors:

Arthur Raymond McFadden - East Brunswick NJ
Daniel Eugene Aultz - Middlesex NJ
Assignee:

American Hoechst Corporation - Bridgewater NJ
International Classification:

C07D33324
A01N 900
US Classification:

2603322C
Abstract:

Heteroarylbenzoxepin-acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and processes for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.

Oxopyridobenzoxepin-Acetic Acids And Derivatives Thereof Useful As Antiinflammatory And Analgesic Agents
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US Patent:

41247132, Nov 7, 1978
Filed:

Apr 19, 1977
Appl. No.:

5/788782
Inventors:

Arthur R. McFadden - East Brunswick NJ
Daniel E. Aultz - Middlesex NJ
Assignee:

American Hoechst Corporation - Bridgewater NJ
International Classification:

A61K 31435
C07D49104
US Classification:

424256
Abstract:

Oxopyridobenzoxepin acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and processes for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.

Dihydro-Dibenzoxepines-Thiepines And -Morphanthridones, Compositions And Use
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US Patent:

43351220, Jun 15, 1982
Filed:

Mar 18, 1981
Appl. No.:

6/225122
Inventors:

Arthur R. McFadden - East Brunswick NJ
Daniel E. Aultz - Middlesex NJ
Assignee:

Hoechst-Roussel Pharmaceuticals Inc. - Somerville NJ
International Classification:

A61K 31335
A61K 3155
C07D22320
C07D31312
US Classification:

424244
Abstract:

The invention relates to diuretic dihydro-dibenzoxepines-thiepines and -morphanthridones of the formula ##STR1## wherein R is ##STR2## where R. sup. 4 is a hydrogen or an alkyl; R. sup. 1 is hydrogen or alkyl; R. sup. 2 and R. sup. 3 are the same or different and are hydrogen, alkyl or R. sup. 2 and R. sup. 3 are fused to form a pyrrolidino, morpholino, piperidino or azepino ring substituent; Y is hydrogen, halogen and alkoxy, X is ##STR3## where R. sup. 4 is as defined above; m is an integer of 0 or 1; and n is an integer of 2 or 3; and the pharmaceutically acceptable acid addition salts thereof.

Process For Preparing Heteroarylbenzoxepin-Acetic Acids, Precursors And Derivatives Thereof
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US Patent:

43450873, Aug 17, 1982
Filed:

Mar 7, 1980
Appl. No.:

6/128252
Inventors:

Arthur R. McFadden - East Brunswick NJ
Daniel E. Aultz - Middlesex NJ
Assignee:

American Hoechst Corporation - Bridgewater NJ
International Classification:

C07D33316
US Classification:

549 44
Abstract:

Heteroarylbenzoxepin-acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and processes for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.

Oxothienobenzoxepin-Acetic Acids, Precursors And Derivatives Thereof
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US Patent:

40256405, May 24, 1977
Filed:

Aug 26, 1975
Appl. No.:

5/607926
Inventors:

Arthur Raymond McFadden - East Brunswick NJ
Daniel Eugene Aultz - Middlesex NJ
Assignee:

American Hoechst Corporation - Bridgewater NJ
International Classification:

A61K 3138
C07D49702
US Classification:

424275
Abstract:

Oxothienobenzoxepin-acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and process for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.

Oxofuranobenzoxepin-Acetic Acids, Precursors And Derivatives Thereof
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US Patent:

41171527, Sep 26, 1978
Filed:

Apr 19, 1977
Appl. No.:

5/788786
Inventors:

Arthur Raymond McFadden - East Brunswick NJ
Daniel Eugene Aultz - Middlesex NJ
Assignee:

American Hoechst Corporation - Bridgewater NJ
International Classification:

A61K 3134
C07D30789
US Classification:

424285
Abstract:

Oxofuranobenzoxepin-acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and processes for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.

Oxopyrrolobenzoxepin-Acetic Acids, Precursors And Derivatives Thereof
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US Patent:

41073215, Aug 15, 1978
Filed:

Apr 19, 1977
Appl. No.:

5/788787
Inventors:

Arthur Raymond McFadden - East Brunswick NJ
Daniel Eugene Aultz - Middlesex NJ
Assignee:

American Hoechst Corporation - Bridgewater NJ
International Classification:

A61K 31415
US Classification:

424274
Abstract:

Oxopyrrolobenzoxepin-acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and processes for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.