Dr. January graduated from the University of Iowa Carver College of Medicine in 1976. He works in Madison, WI and specializes in Cardiovascular Disease. Dr. January is affiliated with Monroe Clinic, University Of Wisconsin Hospital and William S Middleton Memorial Veterans Hospital.
University of Iowa - Doctor of Philosophy University of Iowa, Roy J. and Lucille A. Carver College of Medicine - Doctor of Medicine Bernard Mitchell Hospital-University of Chicago Hospitals - Fellowship - Cardiology Bernard Mitchell Hospital-University of Chicago Hospitals - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine American Board of Internal Medicine Sub-certificate in Cardiovascular Disease (Internal Medicine)
Craig T. January - Madison WI, US Christine Anne Klemens - Green Bay WI, US Brian Patrick Delisle - Lexington KY, US Blake D. Anson - Belleville WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
C12N 5/00
US Classification:
435325
Abstract:
We disclose a cell having double mutations of the hERG gene that lead to charge reversal amino acid substitutions at residues 466 and 534 of the wild type Kv11. 1 channel protein. These double charge reversal mutations result in cells having constitutively open Kv11. 1 channels. Such cells could be used in a method of testing development-stage drugs and other compounds for Kv11. 1 channel block activity.
A method of shortening prolonged QT intervals in a patient with a trafficking defective HERG mutation is disclosed. In one embodiment, this method comprises the step of treating the patient with an effective amount of fexofenadine whereby the patient's prolonged QT interval is shortened.
A method of shortening prolonged QT intervals in a patient with a trafficking defective HERG mutation is disclosed. In one embodiment, this method comprises the step of treating the patient with an effective amount of fexofenadine whereby the patient's prolonged QT interval is shortened.
Name / Title
Company / Classification
Phones & Addresses
Craig T. January Medical Doctor
University of Wisconsin Hospital and Clinics General Hospital Vocational School · Medical Doctor's Office · General Hospital Medical Doctor's Office · Medical Lab · Medical Laboratory · General Hospital College/University · Diagnostic Radiology · Ofcsclns of Mdl Dr
1300 University Ave, Madison, WI 53706 600 Highland Ave, Madison, WI 53792 608 263-4910, 608 263-4787, 608 263-1530, 608 263-7001
Craig Taylor January
Craig January MD,PHD Cardiologist · Internist
600 Highland Ave, Madison, WI 53792 608 263-1530
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