Steven C. Quay - Edmonds WA, US Gordon Brandt - Issaquah WA, US Mary S. Kleppe - Kingston WA, US Conor J. MacEvilly - Seattle WA, US
Assignee:
Nastech Pharmaceutical Company Inc. - Rothell WA
International Classification:
A61K 38/17 A61K 38/28 C07K 14/435
US Classification:
514 12, 530324, 530303
Abstract:
Pharmaceutical compositions and methods are described comprising at least one Y2 receptor-binding peptide, such as peptide YY(PYY), Neuropeptide Y (NPY) or Pancreatic Peptide (PP) and one or more mucosal delivery-enhancing agents for enhanced nasal mucosal delivery of the peptide YY, for treating a variety of diseases and conditions in mammalian subjects, including obesity.
Compositions And Methods For Enhanced Mucosal Delivery Of Y2 Receptor-Binding Peptides And Methods For Treating And Preventing Obesity
Steven C. Quay - Edmonds WA, US Gordon Brandt - Issaquah WA, US Mary S. Kleppe - Kingston WA, US Conor J. MacEvilly - Seattle WA, US
Assignee:
Nastech Pharmaceutical Company Inc. - Bothell WA
International Classification:
A61K 38/17 A61K 38/28 C07K 14/435 B05B 11/02
US Classification:
514 12, 530324, 530303, 222631
Abstract:
Pharmaceutical compositions and methods are described comprising at least one Y2 receptor-binding peptide, such as peptide YY(PYY), Neuropeptide Y (NPY) or Pancreatic Peptide (PP) and one or more mucosal delivery-enhancing agents for enhanced nasal mucosal delivery of the peptide YY, for treating a variety of diseases and conditions in mammalian subjects, including obesity.
Compositions And Methods For Enhanced Mucosal Delivery Of Y2 Receptor-Binding Peptides And Methods For Treating And Preventing Obesity
Pharmaceutical compositions and methods are described comprising at least one Y2 receptor-binding peptide, such as peptide YY(PYY), Neuropeptide Y (NPY) or Pancreatic Peptide (PP) and one or more mucosal delivery-enhancing agents for enhanced nasal mucosal delivery of the peptide YY, for treating a variety of diseases and conditions in mammalian subjects, including obesity.
Methods For Determining The Amount Of Peptide Yy In Blood
Charles Foerder - Seattle WA, US Conor MacEvilly - Seattle WA, US
International Classification:
G01N033/53
US Classification:
435007100
Abstract:
A method for determining the total amount of a Y2 receptor-binding such as PYY in a blood sample. Bound PYY is first freed from components in the blood and proteinaceous material in the blood precipitated preferably by the addition of an organic solvent miscible in water such as ethanol. The PYY remains in solution in a supernatant liquid. The supernatant liquid containing the PYY is removed and the total amount of PYY contained therein is determined preferably by means of an radioimmunoassay.
Compositions And Methods For Enhanced Mucosal Delivery Of Pyy Peptide
A pharmaceutical device comprising a composition comprising an aqueous solution of PYY(3-36), a cyclodextrin, and a compound selected from phosphatidylcholine or diglyceride, wherein the cyclodextrin and the compound selected from phosphatidylcholine or diglyceride are present in an amount sufficient to enhance epithelial permeation, and wherein the composition is present in a container; and an actuator fluidly connected to the container, wherein the actuator has a tip which defines a passage through which the solution is ejected to produce a spray of the solution.
Compositions For Enhanced Epithelial Permeation Of Y2 Receptor-Binding Peptides
Steven Quay - Woodinville WA, US Gordon Brandt - Issaquah WA, US Mary Kleppe - Snohomish WA, US Conor MacEvilly - Seattle WA, US
International Classification:
A61K 38/22 A61K 31/724
US Classification:
514012000, 514058000
Abstract:
Pharmaceutical compositions comprising a PYY peptide, a cyclodextrin, and a compound selected from phosphatidylcholine or diglyceride, wherein the cyclodextrin and the compound selected from phosphatidylcholine or diglyceride are present in an amount sufficient to enhance epithelial permeation.
Coldwell Banker Danforth, Northgate 2111 N. Northgate Way, Seattle, WA 98133 206 349-8477 (Office), 206 349-8477 (Cell)
Experience:
6 years
Description:
Hi there I'm a Realtor, real estate educator and a real estate therapist of varying proportions depending the particular client I'm working with and the particular stage of the purchase or sale we are in. I focus on Seattle neighborhoods north of downtown including Ballard, Magnolia, Queen Anne..basically all neighborhoods north of the Ship Canal but have also worked with buyers and sellers on the East Side, South Seattle and as far north as Mill Creek. I work with both Seattle home buyers and sellers. My real estate philosophy is that I'd be lying if I said buying or selling a home wasn't a wee bit stressful but it should also be fun experience. In my previous life I was a research biochemist / chemist. Failed to cure all major and minor diseases, so I decided to become a Realtor instead. Please contact me with any real estate related questions that you may have. Thanks for reading! Conor
Keller Williams Realty Greater Seattle
Seattle Realtor
Re/Max on Market Dec 2017 - Jul 2019
Seattle Realtor
Coldwell Banker Danforth May 2008 - Dec 2017
Realtor
Nastech Pharmaceutical Jan 2003 - Apr 2008
Senior Manager, Analytical Services
Oxis International 1999 - 2001
Manager
Education:
University of London 1987 - 1992
Doctorates, Doctor of Philosophy, Biochemistry
School of Food and Nutritional Sciences 1982 - 1986
Bachelors, Bachelor of Science, Biochemistry
Skills:
Real Estate Sellers Real Estate Transactions Relocation Foreclosures Investment Properties Due Diligence First Time Home Buyers Short Sales Property Contract Negotiation Negotiation Real Property Pharmaceutical Industry Brokerage Investors Real Estate Development Resellers Selling Luxury Referrals Licensing Move Up Buyers Residential Homes Townhomes Real Estate Economics Strategy Budgets Property Management Sales Reo Small Business Buyer Representation Listings New Home Sales Commercial Real Estate Relocation Buyers Fha Condos Leases Abr Biotechnology Rentals Buyers Single Family Homes Mortgage Lending Seller Representation Hud Investments New Homes