Jian Chen - Princeton NJ Ellen Filvaroff - San Francisco CA Sherman Fong - Alameda CA Audrey Goddard - San Francisco CA Paul Godowski - Burlingame CA Christopher Grimaldi - San Francisco CA Austin Gurney - Belmont CA Hanzhong Li - San Mateo CA Kenneth Hillan - San Francisco CA Daniel Tumas - Orinda CA Menno VanLookeren - San Francisco CA Richard Vandlen - Hillsborough CA Colin Watanabe - Moraga CA P. Mickey Williams - Half Moon Bay CA William I. Wood - Hillsborough CA Daniel Yansura - Pacifica CA
Assignee:
Genentech, Inc. - South San Francisco
International Classification:
A61K 4505
US Classification:
424 852, 530351, 5303873, 435 697
Abstract:
The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
Cytokine Receptor And Nucleic Acids Encoding The Same
Audrey Goddard - San Francisco CA Paul J. Godowski - Hillsborough CA Austin L. Gurney - Belmont CA Colin K. Watanabe - Moraga CA William I. Wood - Hillsborough CA
The present invention is directed to novel cytokine receptors having sequence similarity to AF18497_1 and to nucleic acid molecules encoding those cytokine receptors. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Compositions And Methods For The Diagnosis And Treatment Of Tumor
Wei-Qiang Gao - Palo Alto CA, US Audrey Goddard - San Francisco CA, US Austin L. Gurney - Belmont CA, US Colin K. Watanabe - Moraga CA, US William I. Wood - Hillsborough CA, US
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Secreted And Transmembrane Polypeptides And Nucleic Acids Encoding The Same
Napoleone Ferrara - San Francisco CA, US Wei-Qiang Gao - Foster City CA, US Audrey Goddard - San Francisco CA, US Austin L. Gurney - Belmont CA, US Colin K. Watanabe - Moraga CA, US William I. Wood - Hillsborough CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K016/00 C12P021/08
US Classification:
5303871, 5303881, 5303873, 5303913
Abstract:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Secreted And Transmembrane Polypeptides And Nucleic Acids Encoding The Same
Kevin P. Baker - Darnestown MD, US David Botstein - Belmont CA, US Luc Desnoyers - San Francisco CA, US Dan L. Eaton - San Rafael CA, US Napoleone Ferrara - San Francisco CA, US Sherman Fong - Alameda CA, US Wei-Qiang Gao - Palo Alto CA, US Audrey Goddard - San Francisco CA, US Paul J. Godowski - Hillsborough CA, US J. Christopher Grimaldi - San Francisco CA, US Austin L. Gurney - Belmont CA, US Kenneth J. Hillan - San Francisco CA, US James Pan - Belmont CA, US Nicholas F. Paoni - Belmont CA, US Margaret Ann Roy - San Francisco CA, US Victoria Smith - Burlingame CA, US Timothy A. Stewart - San Francisco CA, US Daniel Tumas - Orinda CA, US Colin K. Watanabe - Moraga CA, US P. Mickey Williams - Half Moon Bkay CA, US William I. Wood - Hillsborough CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12N015/12 C12N015/63 C07K014/00
US Classification:
435 691, 4353201, 536 691, 530350
Abstract:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Secreted And Transmembrane Polypeptides And Nucleic Acids Encoding The Same
Luc Desnoyers - San Francisco CA, US Audrey Goddard - San Francisco CA, US Paul J. Godowski - Hillsborough CA, US Austin L. Gurney - Belmont CA, US Colin K. Watanabe - Moraga CA, US William I. Wood - Hillsborough CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K016/28 C07K014/00 C12N015/62
US Classification:
5303871, 530350, 435 691, 536 235
Abstract:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Secreted And Transmembrane Polypeptides And Nucleic Acids Encoding The Same
Napoleone Ferrara - San Francisco CA, US Audrey Goddard - San Francisco CA, US Paul J. Godowski - Hillsborough CA, US Austin L. Gurney - Belmont CA, US James Pan - Belmont CA, US Colin K. Watanabe - Moraga CA, US William I. Wood - Hillsborough CA, US
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptide of the present invention and to methods for producing the polypeptides of the present invention.
Secreted And Transmembrane Polypeptides And Nucleic Acids Encoding The Same
Napoleone Ferrara - San Francisco CA, US Audrey Goddard - San Francisco CA, US Paul J. Godowski - Hillsborough CA, US Austin L. Gurney - Belmont CA, US James Pan - Belmont CA, US Colin K. Watanabe - Moraga CA, US William I. Wood - Hillsborough CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K016/28 C07K014/00 C07K016/46 A61K038/00
US Classification:
5303871, 530350, 514 2, 435 691
Abstract:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.