Claude Dufresne from Winter Garden, FL, age 64

Us Patents

Method And Apparatus For Automatically Isolating Microbial Species
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US Patent:

20080318310, Dec 25, 2008
Filed:

Oct 7, 2005
Appl. No.:

11/664486
Inventors:

Claude Dufresne - East Brunswick NJ, US
Gary S. Kath - Scotch Plains NJ, US
Gregory W. King - Carteret NJ, US
Prakash S. Masurekar - Warren NJ, US
Salvatore J. Siciliano - East Brunswick NJ, US
Janet M. Sigmund - Cranford NJ, US
Neal R. Simpson - Frenchtown NJ, US
Stephen Skwish - East Brunswick NJ, US
Assignee:

MERCK & CO., INC. - Rahway NJ
International Classification:

C12M 1/26
US Classification:

4353091
Abstract:

This invention relates to an apparatus for streaking a sample on a media-coated (agar) plate in a predefined pattern utilizing a plate carousel system to house and retrieve a plate to a fixed location, a streaking mechanism having a floating stylus having a tip capable of gliding over the agar surface and depositing a sample onto the surface of the agar, a sample dispensing system and an optional wash station.

Cholesterol-Lowering Agents
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US Patent:

52832562, Feb 1, 1994
Filed:

Jul 22, 1992
Appl. No.:

7/918727
Inventors:

Claude Dufresne - East Brunswick NJ
Josep Guarro - Tarragona, ES
Leeyuan Huang - Watchung NJ
Yu L. Kong - Edison NJ
Russell B. Lingham - Watchung NJ
Maria S. Meinz - Somerset NJ
Keith C. Silverman - Somerset NJ
Sheo B. Singh - Edison NJ
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

A61K 31335
C07D31908
US Classification:

514452
Abstract:

This invention relates to compounds of structural formula (I): ##STR1## which are squalene synthase inhibitors and thus useful as cholesterol lowering agents and antifungal agents. These compounds are also inhibitors of farnesyl protein transferase and farnesylation of the oncogene protein Ras and thus useful in treating cancer. This invention also relates to a process for obtaining compounds of structural formula (I).

Cholesterol Lowering Compounds
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US Patent:

53109490, May 10, 1994
Filed:

Sep 2, 1992
Appl. No.:

7/939258
Inventors:

Claude Dufresne - East Brunswick NJ
Prakash S. Masurekar - Warren NJ
Leslie A. Ferrell - Cranford NJ
Deborah L. Zink - Manalapan NJ
Margaret S. Sosa - Elizabeth NJ
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

C07D31904
US Classification:

549363
Abstract:

New Zaragozic acids have been isolated from a culture of MF5465. These compounds and their derivatives are active as squalene synthetase inhibitors and are useful in the treatment of hypercholesterolemia.

Cholesterol Lowering Compounds
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US Patent:

52603326, Nov 9, 1993
Filed:

Feb 7, 1992
Appl. No.:

7/832550
Inventors:

Claude Dufresne - East Brunswick NJ
Assignee:

Merci & Co., Inc. - Rahway NJ
International Classification:

A61K 31335
C07D31908
US Classification:

514452
Abstract:

New Zaragozic acids have been isolated from a culture of MF5465. These compounds and their derivatives are active as squalene synthetase inhibitors and are useful in the treatment of hypercholesterolemia.

Novel Squalene Synthetase Inhibitors
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US Patent:

51029073, Apr 7, 1992
Filed:

Sep 13, 1990
Appl. No.:

7/582452
Inventors:

James D. Bergstrom - Neshanic NJ
Claude Dufresne - Edison NJ
Leeyuan Huang - Watchung NJ
Mary Nallin - Westfield NJ
Janet C. Onishi - Mountainside NJ
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

C07D31914
A61K 3135
US Classification:

514456
Abstract:

This invention relates to compounds of structural formula (I): ##STR1## which are squalene synthetase inhibitors and thus useful as cholesterol lowering agents.

Acyclic Tricarboxylic Acid Compounds
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US Patent:

52547272, Oct 19, 1993
Filed:

Oct 19, 1992
Appl. No.:

7/962547
Inventors:

Claude Dufresne - East Brunswick NJ
E. Tracy T. Jones - Solana Beach CA
Leslie A. Ferrell - Cranford NJ
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

C07L 5948
US Classification:

562470
Abstract:

Two acyclic tricarboxylic acid compounds have been isolated from the fermentation of Sporormiella intermedia. The compounds and their derivatives may be used as antifungal agents, cholesterol lowering agents and as anticancer agents.

Cholesterol Lowering Compounds
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US Patent:

55062628, Apr 9, 1996
Filed:

Nov 10, 1993
Appl. No.:

8/146100
Inventors:

Robert M. Burk - Laguna Beach CA
William H. Parsons - Edison NJ
John J. Acton - Cranford NJ
Gregory D. Berger - Belle Mead NJ
Tesfaye Biftu - Westfield NJ
Robert L. Bugianesi - Colonia NJ
Yuan-Ching P. Chiang - Scotch Plains NJ
Claude Dufresne - East Brunswick NJ
Narindar N. Girotra - Old Bridge NJ
Robert W. Marquis - Iselin NJ
Sandra P. Plevyak - Edison NJ
Mitree M. Ponpipom - Branchburg NJ
Lori L. Whiting - West Carrollton OH
James D. Bergstrom - Neshanic NJ
Conrad Santini - Warren NJ
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

A61K 31335
A61K 31365
C07D40506
C07D31904
US Classification:

514452
Abstract:

Disclosed herein are compounds of structural formula (I) ##STR1## which are useful as cholesterol lowering agents. These compounds are also useful as inhibitors of squalene synthetase, inhibitors of fungal growth, inhibitors of farnesyl-protein transferase and farnesylation of the oncogene protein Ras. These compounds are also useful in the treatment of cancer.

Squalene Synthetase Inhibitors
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US Patent:

51323206, Jul 21, 1992
Filed:

Mar 21, 1990
Appl. No.:

7/496734
Inventors:

James D. Bergstrom - Neshanic NJ
Otto D. Hensens - Red Bank NJ
Claude Dufresne - Edison NJ
Leeyuan Huang - Watchung NJ
Janet C. Onishi - Mountainside NJ
Deborah L. Zink - Manalapan NJ
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

A61K 31335
C07D31908
US Classification:

514452
Abstract:

This invention relates to compounds of structural formula (I): ##STR1## which are squalene synthetase inhibitors and thus useful as cholesterol lowering agents.

Claude Dufresne - Lawyer

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Office:

Dufresne Hebert Comeau

Specialties:

Labor Law
Employment Law
Collective Bargaining
Arbitration Law

ISLN:

907728243

Admitted:

1975

Law School:

Montreal University, LL.L., 1975

Isbn (Books And Publications)

Histoire De L'Operette
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Author:

Claude Dufresne
ISBN #:

2092845675

Le Mystere Du Masque De Fer
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Author:

Claude Dufresne
ISBN #:

2235021883

Balzac Et Les Femmes
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Author:

Claude Dufresne
ISBN #:

2235022103

Morny: L'Homme Du Second Empire
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Author:

Claude Dufresne
ISBN #:

2262002940

L'Imperatrice Eugenie, Ou, Le Roman D'Une Ambitieuse
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Author:

Claude Dufresne
ISBN #:

2262003955

Yvonne Printemps: Le Doux Parfum Du Peche
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Author:

Claude Dufresne
ISBN #:

2262005176

Ce Jour-La, La Victoire: 1918
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Author:

Claude Dufresne
ISBN #:

2262005893

La Roue De La Fortune: Les Jeux De Hasard De L'Antiquite A Nos Jours
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Author:

Claude Dufresne
ISBN #:

2262007322

Chief Executive Officer

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Location:

Princeton, NJ

Industry:

Biotechnology

Work:

Scienion - Princeton NJ since Jan 2013
Vice President Business Development, North America
Scienion - Princeton NJ 2012 - Jan 2013
Scientific Business Development Director
Kalosyn Consulting Services - East Brunswick NJ Jan 2012 - Dec 2012
Owner
Merck - Kenilworth, NJ Dec 2010 - Nov 2011
Automation and IT Manager
Merck Research Laboratories, Rahway, New Jersey Apr 2009 - Dec 2010
Team Leader Automation and Informatics

Education:

University of Alberta 1982 - 1986
McGill University 1979 - 1982

Skills:

Drug Discovery
Biotechnology
Assay Development
Lifesciences
Laboratory Automation
R&D
Pharmaceutical Industry
High Throughput Screening
In Vitro
Life Sciences
Technology Transfer
Drug Development
Chemistry
Validation
Laboratory
Biomarker Discovery
Immunology
Infectious Diseases
Pharmaceutics
Lead Change
Cell
Clinical Development
Management
Genomics
Organic Synthesis
Medical Devices
Commercialization
Lims
Medicinal Chemistry
Biomarkers
Pharmacology
Biopharmaceuticals
Cross Functional Team Leadership
Software Development
21 Cfr Part 11
Instrumentation
New Business Development
Microarray
Iso Certifications
Strategic Alliances
Development of Sales
Project Planning
Microarrays
Single Cell

Languages:

French
German

Certifications:

Iso 13485 Internal Auditor

Vice President Business Development, North America At Scienion

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Position:

Vice President Business Development, North America at Scienion

Location:

Princeton, New Jersey

Industry:

Biotechnology

Work:

Scienion - Princeton NJ since Jan 2013
Vice President Business Development, North America
Scienion - Princeton NJ 2012 - Jan 2013
Scientific Business Development Director
Kalosyn Consulting Services - East Brunswick NJ Jan 2012 - Dec 2012
Owner
Merck - Kenilworth, NJ Dec 2010 - Nov 2011
Automation and IT Manager
Merck Research Laboratories, Rahway, New Jersey Apr 2009 - Dec 2010
Team Leader Automation and Informatics

Education:

University of Alberta 1982 - 1986
McGill University 1979 - 1982

Skills:

Laboratory Automation
Management
Project Planning
Software Development
Assay Development
Lifesciences
Biotechnology
Pharmaceutical Industry
Drug Discovery
Validation
R&D
Technology Transfer
Cross-functional Team Leadership
Microarrays
Instrumentation
New Business Development
21 CFR Part 11
Pharmacology
Cell
Medical Devices
High Throughput Screening
Microarray
Development of Sales
LIMS
Genomics
Biopharmaceuticals
Infectious Diseases
In Vitro

Languages:

French