Michael Joseph Luzzio - Groton CT, US Kevin Daniel Freeman-Cook - Clinton CT, US Samit Kumar Bhattacharya - Niantic CT, US Matthew Merrill Hayward - Old Lyme CT, US Catherine Angela Hulford - North Stonington CT, US Christopher Lowell Autry - New London CT, US Xumiao Zhao - Groton CT, US Jun Xiao - Waterford CT, US Kendra Louise Nelson - Mystic CT, US
Assignee:
Pfizer Inc - New York NY
International Classification:
C07D 239/48 C07D 403/12 A61K 31/506
US Classification:
51425505, 544295
Abstract:
The present invention relates to a compound of the formula I.
Sulfonyl Amide Derivatives For The Treatment Of Abnormal Cell Growth
Michael Joseph Luzzio - Groton CT, US Kevin Daniel Freeman-Cook - Clinton CT, US Samit Kumar Bhattacharya - Niantic CT, US Matthew Merrill Hayward - Old Lyme CT, US Catherine Angela Hulford - North Stonington CT, US Christopher Lowell Autry - New London CT, US Xumiao Zhao - East Lyme CT, US Jun Xiao - Waterford CT, US Kendra Louise Nelson - Mystic CT, US
Michael Joseph Luzzio - Groton CT, US Kevin Daniel Freeman-Cook - Clinton CT, US Samit Kumar Bhattacharya - Niantic CT, US Matthew Merrill Hayward - Old Lyme CT, US Catherine Angela Hulford - North Stonington CT, US Christopher Lowell Autry - New London CT, US Xumiao Zhao - East Lyme CT, US Jun Xiao - Waterford CT, US Kendra Louise Nelson - Mystic CT, US
International Classification:
C07D 239/48 C07D 403/12
US Classification:
544122, 544295, 544296, 544323, 544324
Abstract:
The present invention relates to a compound of the formula I.
Bicyclic Pyrimidine And Pyrimidine Derivatives Useful As Anticancer Agents
The invention relates to compounds of the formulas 1 and 2 and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, Rand Rare as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formulas 1 and 2 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formulas 1 and 2.
Sulfonyl Amide Derivatives For The Treatment Of Abnormal Cell Growth
- New York NY, US Kevin Daniel Freeman-Cook - Clinton CT, US Samit Kumar Bhattacharya - Niantic CT, US Matthew Merrill Hayward - Old Lyme CT, US Catherine Angela Hulford - North Stonington CT, US Christopher Lowell Autry - New London CT, US Xumiao Zhao - East Lyme CT, US Jun Xiao - Waterford CT, US Kendra Louise Nelson - Mystic CT, US
The present invention relates to a compound of the formula Iwherein Rto R, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
Sulfonyl Amide Derivatives For The Treatment Of Abnormal Cell Growth
- New York NY, US Kevin Daniel Freeman-Cook - Clinton CT, US Samit Kumar Bhattacharya - Niantic CT, US Matthew Merrill Hayward - Old Lyme CT, US Catherine Angela Hulford - North Stonington CT, US Christopher Lowell Autry - New London CT, US Xumiao Zhao - East Lyme CT, US Jun Xiao - Waterford CT, US Kendra Louise Nelson - Mystic CT, US
The present invention relates to a compound of the formula Iwherein Rto R, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
Sulfonyl Amide Derivatives For The Treatment Of Abnormal Cell Growth
- New York NY, US Kevin D. Freeman-Cook - Clinton CT, US Samit K. Bhattacharya - Niantic CT, US Matthew M. Hayward - Old Lyme CT, US Catherine A. Hulford - North Stonington CT, US Christopher L. Autry - New London CT, US Xumiao Zhao - East Lyme CT, US Jun Xiao - Waterford CT, US Kendra L. Nelson - Mystic CT, US
The present invention relates to a compound of the formula Iwherein Rto R, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
Sulfonyl Amide Derivatives For The Treatment Of Abnormal Cell Growth
- New York NY, US Kevin D. Freeman-Cook - Clinton CT, US Samit K. Bhattacharya - Niantic CT, US Matthew M. Hayward - Old Lyme CT, US Catherine A. Hulford - North Stonington CT, US Christopher L. Autry - New London CT, US Xumiao Zhao - East Lyme CT, US Jun Xiao - Waterford CT, US Kendra L. Nelson - Mystic CT, US
International Classification:
C07D 401/12
Abstract:
The present invention relates to a compound of the formula Iwherein Rto R, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.