Cheryl A Murphy

US Patent:

6900061, May 31, 2005

Filed:

Aug 23, 2002

Appl. No.:

10/227088

Inventors:

Igor P. Smirnov - Brookline MA, US
Andrew J. Tomlinson - Wayland MA, US
Lawrence A. Haff - Westborough MA, US
Jennifer M. Campbell - Somerville MA, US
Cheryl E. Murphy - Hudson NH, US

Assignee:

PerSeptive BioSystems, Inc. - Framingham MA
MDS Inc. - Toronto

International Classification:

G01N024/00
H01J049/00

US Classification:

436173, 250288

Abstract:

A sample plate for a MALDI process is provided which comprises an electrically conductive substrate having a hydrophobic coating whose thickness and hydrophobic character can be modified by changing the coating substrate and/or the concentration of the substrate. Different coating substances that have provided optimal performance of the sample plate for reproducible deposition and analysis by MALDI-MS and MALDI-MS/MS processes of analyte mixtures include synthetic waxes such as paraffin compositions, lipids, organic acids, silicon-containing compounds, silica polymers and natural waxes. Metal polishes that have been used to clean and regenerate plate surfaces have also provided a sample plate that has optimal performance for reproducible deposition and analysis by MALDI-MS and MALDI-MS/MS processes of analyte mixtures.

US Patent:

20050196789, Sep 8, 2005

Filed:

Feb 4, 2005

Appl. No.:

11/051807

Inventors:

Andrew Tomlinson - Wayland MA, US
Cheryl Murphy - Hudson NH, US

Assignee:

Applera Corporation - Framingham MA

International Classification:

C12Q001/68

US Classification:

435006000

Abstract:

Methods and kits for preparing biologically derived fluids for subsequent biomarker analysis by mass spectrometry are provided.

Address:

315 Craig St, Greensboro, NC 27406

VIN:

4T1BE46K07U121958

Make:

TOYOTA

Model:

CAMRY

Year:

2007