Paul Samuel Zerwekh - Shawsville VA, US Jeffrey C. Lesho - Brookville MD, US Robert William Lynn - Germantown MD, US Carrie R. Lorenz - Woodbine MD, US Casey J. O'Connor - Gaithersburg MD, US Steven J. Walters - Ellicott City MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
F21V 9/16
US Classification:
2504581
Abstract:
The present invention provides systems and methods for attenuating the effect of ambient light on optical sensors and for measuring and compensating quantitatively for the ambient light.
Systems And Methods For Extending The Useful Life Of Optical Sensors
Jeffery C. Lesho - Brookeville MD, US Carrie R. Lorenz - Woodbine MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
G01N 21/64
US Classification:
2504591, 2502521
Abstract:
The present invention provides a method for increasing the lifetime of an optical sensor. In one aspect, the method includes the step of configuring the optical sensor so that the duty cycle of sensor's radiant source is less than 100% over a continuous period amount of time when the sensor is periodically obtaining data regarding an analyte. By operating the sensor according to the above inventive method, the indicator molecules of the optical sensor are not excited during the entire continuous period of time during which the sensor is needed to provide data regarding the presence or concentration of a substance. Thus, the method increases the life of the indicator molecules.
System And Method For Attenuating The Effect Of Ambient Light On An Optical Sensor
Paul Samuel Zerwekh - Shawsville VA, US Jeffrey C. Lesho - Brookville MD, US Robert William Lynn - Germantown MD, US Carrie R. Lorenz - Woodbine MD, US Casey J. O'Connor - Gaithersburg MD, US Steven J. Walters - Ellicott City MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
G01J 1/16
US Classification:
250214AL
Abstract:
The present invention provides systems and methods for attenuating the effect of ambient light on optical sensors and for measuring and compensating quantitatively for the ambient light.
Non-Covalent Immobilization Of Indicator Molecules
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
G01N 21/63 G01N 21/64
US Classification:
436172, 436 85, 506 43
Abstract:
The invention relates to immobilization methods, in particular for immobilizing indicator molecules on supports such as sensors and to sensors having those molecules immobilized to their surface. Non-covalent immobilization of macromolecular indicator molecules on those supports via mechanical interlacing with polymers at the surface of a support and via ionic bonding via charged moieties of indicator molecules and ionic groups on the surface of the support are disclosed.
System And Method For Attenuating The Effect Of Ambient Light On An Optical Sensor
Paul Samuel Zerwekh - Shawsville VA, US Jeffrey C. Lesho - Brookeville MD, US Robert W. Lynn - Germantowm MD, US Carrie R. Lorenz - Woodbine MD, US Casey J. O'Connor - Gaithersburg MD, US Steven J. Walters - Ellicott City MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
G01J 1/16 F21V 9/16
US Classification:
250214AL, 2504581
Abstract:
The present invention provides systems and methods for attenuating the effect of ambient light on optical sensors and for measuring and compensating quantitatively for the ambient light.
Systems And Methods For Extending The Useful Life Of Optical Sensors
Jeffery C. Lesho - Brookeville MD, US Carrie R. Lorenz - Woodbine MD, US
Assignee:
Sensors For Medicine and Science, Inc. - Germantown MD
International Classification:
G01N 21/64
US Classification:
2504591, 2502521
Abstract:
The present invention provides a method for increasing the lifetime of an optical sensor. In one aspect, the method includes the step of configuring the optical sensor so that the duty cycle of sensor's radiant source is less than 100% over a continuous period amount of time when the sensor is periodically obtaining data regarding an analyte. By operating the sensor according to the above inventive method, the indicator molecules of the optical sensor are not excited during the entire continuous period of time during which the sensor is needed to provide data regarding the presence or concentration of a substance. Thus, the method increases the life of the indicator molecules.
System And Method For Attenuating The Effect Of Ambient Light On An Optical Sensor
Arthur Colvin - Mt. Airy MD, US Paul Zerwekh - Shawsville VA, US Jeffrey Lesho - Brookville MD, US Robert Lynn - Germantown MD, US Carrie Lorenz - Woodbine MD, US Casey O'Connor - Gaithersburg MD, US Steven Walters - Ellicott City MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
G01N021/64
US Classification:
250458100
Abstract:
The present invention provides systems and methods for attenuating the effect of ambient light on optical sensors and for measuring and compensating quantitatively for the ambient light.
Housing For A Circuit That Is To Be Implanted In-Vivo And Process Of Making The Same
Arthur Colvin - Mt. Airy MD, US Carrie Lorenz - Woodbine MD, US Casey O'Connor - Gaithersburg MD, US Steven Walters - Ellicott City MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
H01H073/00 H05K005/04 A61B005/00
US Classification:
600310000, 361757000
Abstract:
The present invention provides a biocompatible circuit assembly that includes a circuit encased within a housing. In some embodiments, the housing is a PMMA housing and before the circuit is enclosed within the housing the circuit is encased within a brick of epoxy.
Sensors for Medicine & Science, Inc. since Nov 1998
Staff Scientist
Johns Hopkins Bloomberg School of Public Health Jul 1998 - Nov 1999
Postdoc
Education:
Ohio University 1992 - 1997
Ph.D., Chemistry
Canisius College 1987 - 1992
B.S., Chemistry
Skills:
Biotechnology Hplc Laboratory Medical Devices Fluorescence Product Development R&D Research Life Sciences Biomedical Engineering Characterization Assay Development Clinical Trials Polymers Standard Operating Procedure In Vivo Fluorescence Spectroscopy Fda Gmp Project Management Operations Management Vendor Management Analytical Skills Data Analysis Budgeting Continuous Improvement Contract Management Research and Development Forecasting Product Management Start Ups Sensors Organization Skills People Development People Management Team Management Team Building Cross Functional Team Leadership Employee Training Problem Solving Teaching Teamwork Time Management Management Training Fda Gmp Medical Device R&D Engaging People Process Improvement Communication Business Project Plans Work Effectively Technical Product Development Quality System Scientific Li
Staff Scientist At Sensors For Medicine And Science, Inc.
Wilma Crall Elementary School Galion OH 1981-1985, Nash Elementary School Harleysville PA 1985-1987, Pennfield Middle School Hatfield PA 1987-1989, North Penn Junior High School Lansdale PA 1990-1991