Carolina Rangel

US Patent:

20030236173, Dec 25, 2003

Filed:

Jun 19, 2002

Appl. No.:

10/175589

Inventors:

James Dobson - Houston TX, US
Shauna Hayden - Houston TX, US
Carolina Rangel - Cypress TX, US

International Classification:

C09K007/00

US Classification:

507/110000

Abstract:

Disclosed is a hydrophilic, water soluble polymer concentrate for addition to aqueous liquids to enhance the properties thereof, particularly to increase the viscosity or decrease the fluid loss of well drilling and servicing fluids, the concentrate comprising a hydrophobic, water insoluble liquid, an organophilic clay suspension agent, the water soluble polymer, and a stabilizing agent comprising one or more acids in an amount from about 0.001% to about 1.5%, one or more anionic surfactants in an amount from about 0.001% to about 1.0%, one or more nonionic surfactants in an amount from 0.001% to about 0.625% and, from about 0% to about 0.75% of one or more water soluble organic liquids, wherein the total concentration of the stabilizing agent is from about 0.1% to about 2.5%, these percentages being based on the weight of the concentrate. Preferably the stabilizing agent is a microemulsion comprising the acid(s), the anionic surfactant(s), the nonionic surfactant(s), and the water soluble organic liquid(s), and further comprising from about 0.0005% to about 1.0% of one or more water insoluble solvents, and from about 0.001% to about 2.0% water.

US Patent:

20070292438, Dec 20, 2007

Filed:

Dec 13, 2004

Appl. No.:

10/583466

Inventors:

Stephen Anderson - The Woodlands TX, US
Jane Brennan - Lothian Region, GB
Frederic de Sauvage - Foster City CA, US
Zhiyong Ding - Longmont CO, US
Joel Edwards - The Woodlands TX, US
Nelda Fikes - Spring TX, US
Wenhu Huang - San Diego CA, US
Wenjun Ouyang - Foster City CA, US
Carolina Rangel - Houston TX, US
Mamta Sangha - Tualatin OR, US
Mary Sparks - Magnolia TX, US
Joseph Trackey - The Woodlands TX, US
Melissa Vetter - Spring TX, US
Ching-Yun Wang - The Woodlands TX, US
Jessica Woodings - Longmont CO, US

International Classification:

A61K 39/395
C07K 16/00
C12N 5/00
C12N 5/06
C12Q 1/02
G01N 33/00

US Classification:

424172100, 435029000, 435325000, 435352000, 435375000, 530387100, 800003000

Abstract:

The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO224, PRO9783, PRO1108, PRO34000, PRO240, PRO943, hu A33, PRO230, PRO178, PRO1199, PRO4333, PRO1336, PRO19598, PRO1083, hu TRPM2 or PRO1801 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.

US Patent:

20080189799, Aug 7, 2008

Filed:

Oct 26, 2007

Appl. No.:

11/978234

Inventors:

Liangfen Fan - Spring TX, US
Glenn Friedrich - Houston TX, US
Laurie Jeanette Minze - Katy TX, US
Charles Montgomery - Jay OK, US
Bobby Joe Payne - The Woodlands TX, US
Carolina Rangel - Houston TX, US
Arthur T. Sands - The Woodlands TX, US
Tracy Ellen Willis Sevaux - Conroe TX, US
Mary Jean Sparks - Magnolia TX, US
Peter Vogel - The Woodlands TX, US
Brian Zambrowicz - The Woodlands TX, US

International Classification:

C12N 15/11
A01K 67/027

US Classification:

800 6, 800 18

Abstract:

The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.

US Patent:

20090077680, Mar 19, 2009

Filed:

Apr 8, 2008

Appl. No.:

12/099465

Inventors:

Alejandro Abuin - The Woodlands TX, US
Joel Edwards - Las Flores CA, US
Charles Montgomery - Jay OK, US
Bobby Joe Payne - The Woodlands TX, US
Carolina Rangel - Houston TX, US
Arthur T. Sands - The Woodlands TX, US
Mary Jean Sparks - Magnolia TX, US
Teresa Gail Townsend - Houston TX, US
Rosemary Girgis - Houston TX, US
Allison Anne Byers Horner - Dickinson TX, US
Peter Vogel - The Woodlands TX, US
Brian Zambrowicz - The Woodlands TX, US

International Classification:

A01K 67/027
C12N 5/06
C07K 16/18

US Classification:

800 18, 435354, 5303871, 5303873, 5303881, 5303891

Abstract:

The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.

US Patent:

20090113564, Apr 30, 2009

Filed:

Mar 28, 2008

Appl. No.:

12/057851

Inventors:

Alejandro Abuin - The Woodlands TX, US
Mark Dominic Borromeo - San Antonio TX, US
Katherin E. Combs - Spring TX, US
Ling Ling Culbertson - Spring TX, US
Zhi-Yong Ding - Longmont CO, US
Joel Edwards - Las Flores CA, US
Liangfen Fan - Spring TX, US
Rosemary Girgis - Houston TX, US
Leslie Jane Green - Conroe TX, US
Allison Anne Byers Horner - Dickinson TX, US
Erin Marie Massey - Conroe TX, US
Dina Rebecca McLain - San Antonio TX, US
Laurie Jeanette Minze - Katy TX, US
Charles Montgomery - Jay OK, US
Bobby Joe Payne - The Woodlands TX, US
Carolina Rangel - Houston TX, US
Arthur T. Sands - The Woodlands TX, US
Tracy Ellen Willis Sevaux - Conroe TX, US
Mary Jean Sparks - Magnolia TX, US
Joy Anne Stala - Dallas TX, US
Peter Vogel - The Woodlands TX, US
Brian Zambrowicz - The Woodlands TX, US

International Classification:

A01K 67/027

US Classification:

800 18

Abstract:

The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.

US Patent:

20090193532, Jul 30, 2009

Filed:

Apr 8, 2008

Appl. No.:

12/099459

Inventors:

Alejandro Abuin - The Woodlands TX, US
Joel A. Edwards - Las Flores CA, US
Charles Montgomery - Jay OK, US
Carolina Rangel - Houston TX, US
Arthur T. Sands - The Woodlands TX, US
Mary Jean Sparks - Magnolia TX, US
Peter Vogel - The Woodlands TX, US
Brian Zambrowicz - The Woodlands TX, US

International Classification:

A01K 67/027

US Classification:

800 18

Abstract:

The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.

US Patent:

20090196876, Aug 6, 2009

Filed:

Oct 18, 2005

Appl. No.:

11/577547

Inventors:

Fred de Sauvage - Foster City CA, US
Dorothy French - San Carlos CA, US
Lino Gonzalez - Menlo Park CA, US
Asja Praetor - Singapore, SG
Weilan Ye - Foster City CA, US
Katherin E. Combs - Spring TX, US
Zhiyong Ding - Longmont CO, US
Allison Anne Byers Horner - Dickinson TX, US
Erin Marie Massey - Conroe TX, US
Charles Montgomery - Jay OK, US
Laurie Jeanette Minze - Katy TX, US
Carolina Rangel - Houston TX, US
Tracy Ellen Willis Sevaux - Conroe TX, US
Mary Jean Sparks - Magnolia TX, US
Joy Anne Stala - The Woodlands TX, US
Peter Vogel - The Woodlands TX, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

A61K 39/395
G01N 33/00
C12N 5/10
C07K 16/18
A61P 27/00
A61P 25/00
A61P 25/18
A61P 25/22
A61P 37/00
A61P 13/12
A61P 3/00
A61P 19/00
A61P 9/00
A61P 35/00
A61P 41/00
A61P 3/10

US Classification:

4241581, 800 3, 435325, 435352, 5303871

Abstract:

The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO194, PRO220, PRO241, PRO284, PRO331, PRO354, PRO355, PRO533, PRO541, PRO725, PRO937, PRO1014, PRO1120, PRO1182, PRO1325, PRO1382, PRO1410, PRO1555, PRO1556, PRO1760, PRO1787, PRO1868, PRO4326, PRO4332, PRO4346, PRO4400, PRO6003, PRO6094, PRO6244, PRO9820, PRO9828, PRO10274, PRO16090, PRO19644, PRO21340, PRO92165, PRO85143, PRO1124, PRO1026 or PRO23370 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.

US Patent:

20090288176, Nov 19, 2009

Filed:

Apr 18, 2007

Appl. No.:

11/814025

Inventors:

Kristi Rae Bollinger - Tomball TX, US
Frederic J. de Sauvage - Foster City CA, US
Joel Edwards - The Woodlands TX, US
Rosemary Girgis - Houston TX, US
Leslie Jane Green - Conroe TX, US
Laurie Jeanette Minze - Katy TX, US
Bobby Joe Payne - Woodlands TX, US
Carolina Rangel - Houston TX, US
Mary Jean Sparks - Magnolia TX, US
Tracy Tzu-Ling Tang - Redwood City CA, US
Peter Vogel - The Woodlands TX, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

G01N 33/00
A61K 39/395
C12N 5/10
C07K 16/00
A01K 67/00

US Classification:

800 3, 4241301, 435325, 435354, 5303871, 800 9

Abstract:

The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO286, PRO706, PRO1800, PRO4354, PRO6029, PRO9739, PRO20044, PRO28631 or PRO34128 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.