Carl Ray Henson

US Patent:

39560694, May 11, 1976

Filed:

Apr 29, 1974

Appl. No.:

5/465039

Inventors:

Charles C. Allain - Los Angeles CA
Carl P. Henson - Alhambra CA

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

G01N 3114
C07G 702

US Classification:

1951035R

Abstract:

Enzymatic assays for determining glucose, creatine phosphokinase or plasma ammonia, wherein nicotinamide adenine dinucleotide is reduced or the reduced form of nicotinamide adenine dinucleotide is oxidized to nicotinamide adenine dinucleotide, are carried out in the presence of about 2 to 50 micromoles per liter of oxalic acid or oxamic acid, or salts thereof. The oxalic acid, oxamic acid and salts thereof inhibit lactic dehydrogenase which causes errors in the assays.