BRIAN TSENG - BOULDER CO, US RICK RABON - BOULDER CO, US LALITH POLEPEDDI - Centennial CO, US MICHAEL M. POLMEAR - Greenwood Village CO, US WARREN MCCLURE - Denver CO, US
Assignee:
UNIVERSITY OF COLORADO - BOULDER CO
International Classification:
A61K 31/74 A61P 21/00
US Classification:
424 7831
Abstract:
A molecular sealant comprising a therapeutically effective amount of a poloxamer capable of sealing a cell or tissue from leaks. A method of treating tissue leakages by applying the above sealant to the tissue or cell in need of treatment. A composition for treating cellular leakages comprising a poloxamer capable of sealing a cell or tissue from leaks in a pharmaceutically acceptable carrier.
The invention provides methods of preventing, treating and ameliorating symptoms of muscular dystrophy. The invention also provides experimental systems for identifying and evaluating such treatments.
Methods Of Treating Sporadic Inclusion Body Myositis
- Basel, CH Ronenn Roubenoff - Brookline MA, US Brian Tseng - Weston MA, US Charles Gubser - Reinach, CH David Glass - Cambridge MA, US
International Classification:
C07K 16/28 A61K 39/00
Abstract:
The disclosure relates to the treatment of sporadic inclusion body myositis and other muscle wasting disorders with novel regimens, which employ a therapeutically effective amount of a myostatin antagonist, e.g., a myostatin binding molecule, e.g., a myostatin antibody or an ActRII receptor binding molecule, an ActRII receptor antibody, such as the bimagrumab antibody.
Methods Of Treating Sporadic Inclusion Body Myositis
Dimitris PAPANICOLAOU - East Hannover NJ, US Ronenn ROUBENOFF - Cambridge MA, US Brian TSENG - Cambridge MA, US Charles GUBSER - Basel, CH David GLASS - Cambridge MA, US
Assignee:
Novartis AG - Basel
International Classification:
C07K 16/28
Abstract:
The disclosure relates to the treatment of sporadic inclusion body myositis and other muscle wasting disorders with novel regimens, which employ a therapeutically effective amount of a myostatin antagonist, e.g., a myostatin binding molecule, e.g., a myostatin antibody or an ActRII receptor binding molecule, an ActRII receptor antibody, such as the bimagrumab antibody.
Team members include eighth-graders Karthik Bharathala and Dhruv Muley, and seventh-graders Catherine Zeng, Brian Tseng and Mark Choi. They were coached by teacher Paul Ricks. Team members had spent all their lunchtimes this year practicing for the bowl, Hopkins Principal Mary Miller said.