Brian M Schlossberg

US Patent:

20130195928, Aug 1, 2013

Filed:

Dec 20, 2012

Appl. No.:

13/722237

Inventors:

PIONEER SURGICAL TECHNOLOGY - Marquette MI, US
Ronald Stewart Hill - Greenville NC, US
Adam MacMillan - Quincy MA, US
Edward Ahn - Dover MA, US
Brian Schlossberg - Chestnut Hill MA, US
Stephen Capistron - Melrose MA, US
William H. Lloyd - Winterville NC, US

Assignee:

PIONEER SURGICAL TECHNOLOGY - Marquette MI

International Classification:

A61L 27/48

US Classification:

424400, 514773, 424577, 424602

Abstract:

The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise particles of a porous, osteoconductive material dispersed in the continuous matrix. The composition can be provided in a dehydrated form. The disclosure further provides methods of preparing the composition in a clinically useful form, methods of using the composition in regenerating bone, and kits including the composition.

US Patent:

D663833, Jul 17, 2012

Filed:

Nov 11, 2010

Appl. No.:

29/378941

Inventors:

Edward S. Ahn - Dover MA, US
Stephen Capistron - Melrose MA, US
Brian Schlossberg - Chestnut Hill MA, US

Assignee:

Pioneer Surgical Technology, Inc. - Marquette MI

International Classification:

2402

US Classification:

D24114

US Patent:

20190358362, Nov 28, 2019

Filed:

Aug 6, 2019

Appl. No.:

16/532799

Inventors:

- Marquette MI, US
Edward S. Ahn - Dover MA, US
Brian M. Schlossberg - Chestnut Hill MA, US

International Classification:

A61L 24/06
A61K 6/08
A61L 24/04
A61L 24/02
A61K 6/033
A61K 6/083

Abstract:

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.

US Patent:

20180264165, Sep 20, 2018

Filed:

May 17, 2018

Appl. No.:

15/982686

Inventors:

- Marquette MI, US
Edward S. Ahn - Dover MA, US
Brian M. Schlossberg - Chestnut Hill MA, US

International Classification:

A61L 24/06
A61K 6/033
A61L 24/04
A61K 6/083
A61K 6/08
A61L 24/02

Abstract:

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.

US Patent:

20170333594, Nov 23, 2017

Filed:

Aug 7, 2017

Appl. No.:

15/670284

Inventors:

- Marquette MI, US
Edward S. Ahn - Dover MA, US
Brian M. Schlossberg - Chestnut Hill MA, US

International Classification:

A61L 24/06
A61K 6/033
A61L 24/02
A61L 24/04
A61K 6/08
A61K 6/083

Abstract:

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.

US Patent:

20160250376, Sep 1, 2016

Filed:

May 9, 2016

Appl. No.:

15/149986

Inventors:

- Marquette MI, US
Edward S. Ahn - Dover MA, US
Brian M. Schlossberg - Chestnut Hill MA, US

International Classification:

A61L 24/06
A61K 6/083
A61K 6/033
A61L 24/02

Abstract:

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.

US Patent:

20150098998, Apr 9, 2015

Filed:

Dec 12, 2014

Appl. No.:

14/568339

Inventors:

- Marquette MI, US
Ronald Stewart Hill - Greenville NC, US
Adam MacMillan - Quincy MA, US
Edward Ahn - Dover MA, US
Brian Schlossberg - Chestnut Hill MA, US
Stephen Capistron - Melrose MA, US
William H. Lloyd - Winterville NC, US

International Classification:

A61L 27/46
A61L 27/56

US Classification:

424489, 424602

Abstract:

The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise particles of a porous, osteoconductive material dispersed in the continuous matrix. The composition can be provided in a dehydrated form. The disclosure further provides methods of preparing the composition in a clinically useful form, methods of using the composition in regenerating bone, and kits including the composition.

US Patent:

20140357754, Dec 4, 2014

Filed:

Aug 15, 2014

Appl. No.:

14/461138

Inventors:

- Marquette MI, US
Edward S. Ahn - Dover MA, US
Brian M. Schlossberg - Chestnut Hill MA, US

International Classification:

A61L 24/04
A61L 24/02

US Classification:

523116, 528341

Abstract:

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.