Brian Joseph Hess

US Patent:

7892347, Feb 22, 2011

Filed:

Dec 17, 2009

Appl. No.:

12/640805

Inventors:

Gerard M. Insley - Limerick, IE
Adrian Sun Wai - Limerick, IE
Donal O'Mahony - Limerick, IE
Paul Higham - Ringwood NJ, US
Joseph P. Zitelli - River Edge NJ, US
Sandra M. Murray - Oradell NJ, US
Brian Hess - Charlestown MA, US

Assignee:

Howmedica Osteonics Corp. - Mahwah NJ

International Classification:

C04B 12/02

US Classification:

106690, 106691, 106 35

Abstract:

The invention is related to a premixed putty calcium phosphate composition comprising at least two calcium phosphate minerals, at least one reaction retarding agent, at least one binding agent, at least one sodium phosphate, and at least one nonaqueous extender, wherein one of said at least two calcium phosphate minerals contains a stabilizing agent.

US Patent:

8034034, Oct 11, 2011

Filed:

Jan 12, 2009

Appl. No.:

12/319815

Inventors:

Brian J. Hess - Charlestown MA, US
Liem T. Vu - Needham MA, US

Assignee:

Howmedica Osteonics Corp. - Mahwah NJ

International Classification:

A61M 5/315

US Classification:

604226, 604 57, 604 64, 604187, 604218, 604236, 606 94

Abstract:

A syringe and a method of using the syringe are disclosed. The syringe includes a longitudinal body having proximal and distal ends and including an aperture between the proximal and distal ends. An injectable material, such as an adhesive bone cement, may be loaded into the body of the syringe through the aperture. After the injectable material is inserted, the aperture may be closed by covering the aperture with an aperture cover. The aperture cover may be configured to slide into a position covering the aperture, or the aperture cover may be placed in a position covering the aperture, such as by pivoting about a hinge. After the aperture is closed, the injectable material may be dispensed from the distal end of the syringe body by depressing a plunger. Depressing the plunger may initiate the closing of the aperture, or the aperture may be closed independently of plunger movement.

US Patent:

8232327, Jul 31, 2012

Filed:

Nov 12, 2009

Appl. No.:

12/616900

Inventors:

Venkat R. Garigapati - Southborough MA, US
Brian J. Hess - Charlestown MA, US
Jon Ahola - Walpole MA, US

Assignee:

Howmedia Osteonics Corp - Mahwah NJ

International Classification:

A61K 6/033
C04B 12/02

US Classification:

523116, 523117, 106691, 4332281

Abstract:

Compositions and methods of their use to adhere a variety of materials together are disclosed herein. The compositions include at least tetra calcium phosphate, an effective amount of a compound that is structurally similar to phosphoserine, and can be mixed with an aqueous solution. The compositions provide adhesive and cohesive strength in both wet and dry environments and exhibit significant bond strength upon curing.

US Patent:

8273803, Sep 25, 2012

Filed:

Dec 8, 2011

Appl. No.:

13/315015

Inventors:

Venkat R. Garigapati - Southborough MA, US
Brian J. Hess - Charlestown MA, US
Jon Ahola - Walpole MA, US

Assignee:

Howmedica Osteonics Corp. - Mahwah NJ

International Classification:

A61L 24/02
C04B 12/02

US Classification:

523116, 523118, 106691

Abstract:

Compositions and methods of their use to adhere a variety of materials together are disclosed herein. The compositions include at least tetra calcium phosphate, an effective amount of a compound that is structurally similar to phosphoserine, and can be mixed with an aqueous solution. The compositions provide adhesive and cohesive strength in both wet and dry environments and exhibit significant bond strength upon curing.

US Patent:

8303599, Nov 6, 2012

Filed:

Sep 22, 2010

Appl. No.:

12/887663

Inventors:

Brian Hess - Charlestown MA, US
Matthew E. Murphy - Pembrokestown, IE

Assignee:

Stryker Leibinger GmbH & Co. KG

International Classification:

A61B 17/56
B65D 83/10
B65D 25/08

US Classification:

606 92, 206219, 206364, 206571

Abstract:

A stand for use with a syringe is structured to engage a portion of the syringe in order to maintain the syringe in an upright position. The stand may include an aperture structured to engage the nozzle or the plunger of the syringe. Another embodiment of the stand may include a protrusion structured to engage the proximal end of the syringe, or a clip structured to engage a handle of the syringe. The stand may include a package portion having compartments for holding various components, such as components of a bone cement preparation kit. The proximal and distal portions of the barrel of the syringe may be separable to provide an opening into the barrel through which an injectable material may be inserted. The plunger of the syringe may also include a plunger rod removably affixed to the plunger tip.

US Patent:

8481065, Jul 9, 2013

Filed:

Dec 16, 2010

Appl. No.:

12/970393

Inventors:

Donal O'Mahony - Limerick, IE
Venkat R. Garigapati - Southborough MA, US
Adrian Sun Wai - Limerick, IE
Brian Hess - Charlestown MA, US
Matthew E. Murphy - Pembrokestown, IE

Assignee:

Howmedica Osteonics Corp. - Mahwah NJ

International Classification:

A61F 2/00
A61F 2/28
A61L 24/00
A61L 24/02
A61L 24/04

US Classification:

424422, 424423, 424426, 424602, 623 1611, 623 2356, 623 2358, 623 2362

Abstract:

The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.

US Patent:

20110277931, Nov 17, 2011

Filed:

May 10, 2011

Appl. No.:

13/104716

Inventors:

Venkat R. Garigapati - Southborough MA, US
Brian J. Hess - Charlestown MA, US
Cassandra L. Kimsey - Hoboken NJ, US
Matthew E. Murphy - Whiterock Hill, IE

International Classification:

A61L 24/04
B32B 37/12
B32B 37/14
C09K 19/52

US Classification:

1563316, 523116, 521182, 25229901, 156327

Abstract:

Certain small molecule amino acid phosphate compounds such as phosphoserine and certain multivalent metal compounds such as calcium phosphate containing cements have been found to have improved properties and form an interpenetrating network in the presence of a polymer that contain either an electronegative carbonyl oxygen atom of the ester group or an electronegative nitrogen atom of the amine group as the bonding sites of the polymer surfaces to the available multivalent metal ions.

US Patent:

20130142781, Jun 6, 2013

Filed:

Dec 3, 2012

Appl. No.:

13/692458

Inventors:

Timothy O'Shea - Cambridge MA, US
Jonathan R. Slotkin - Potomac MD, US
Francis M. Reynolds - Lafayette Hill PA, US
Alex Aimetti - Waltham MA, US
Brian Hess - Charlestown MA, US

Assignee:

INVIVO THERAPEUTICS CORPORATION - Cambridge MA

International Classification:

A61K 47/20
A61K 31/795
A61L 24/04

US Classification:

4241301, 514785, 514 177, 514 44 R, 514169, 424 941, 514626, 514179, 514282, 424 945, 514 84, 514329, 514550

Abstract:

Hydrogels that may be used for treating peripheral nerves and related methods are provided. Synthetic hydrogel sealants, methods of forming synthetic hydrogel sealants, and the use of synthetic hydrogel sealants are provided.