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Asimina Georg Evangelinos

age ~52

from Andover, MA

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Also known as:
  • Asimina Georges Evangelinos
  • Asimina G Evangelinos
  • Asimina T Evangelinos
  • Asimina T Georges
  • Asimina S
Phone and address:
7 Lillian Ter, Andover, MA 01810
978 475-5134
Related to:
Connected to:

Asimina Evangelinos Phones & Addresses

  • 7 Lillian Ter, Andover, MA 01810 • 978 475-5134
  • 255 Independence Dr, Chestnut Hill, MA 02467
  • Providence, RI
  • Boston Clg, MA

Work

  • Position:
    Building and Grounds Cleaning and Maintenance Occupations

Education

  • Degree:
    Bachelor's degree or higher

Us Patents

  • Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

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  • US Patent:
    20050288269, Dec 29, 2005
  • Filed:
    Apr 14, 2005
  • Appl. No.:
    11/107404
  • Inventors:
    Julian Adams - Boston MA, US
    Yun Gao - Southborough MA, US
    Asimina Georges Evangelinos - Chestnut Hill MA, US
    Louis Grenier - Brookline MA, US
    Roger Pak - Boxborough MA, US
    James Porter - Brighton MA, US
    James Wright - Lexington MA, US
  • International Classification:
    A61K031/33
    C07D225/04
  • US Classification:
    514183000, 540461000, 540462000
  • Abstract:
    The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

  • Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

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  • US Patent:
    20060014731, Jan 19, 2006
  • Filed:
    Apr 14, 2005
  • Appl. No.:
    11/108165
  • Inventors:
    Julian Adams - Boston MA, US
    Yun Gao - Southborough MA, US
    Asimina Georges Evangelinos - Chestnut Hill MA, US
    Louis Grenier - Brookline MA, US
    Roger Pak - Boxborough MA, US
    James Porter - Brighton MA, US
    James Wright - Lexington MA, US
  • International Classification:
    C07D 225/04
    C07D 491/02
    A61K 31/33
  • US Classification:
    514183000, 540461000, 540462000
  • Abstract:
    The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

  • Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

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  • US Patent:
    20060019939, Jan 26, 2006
  • Filed:
    Apr 13, 2005
  • Appl. No.:
    11/105203
  • Inventors:
    Julian Adams - Boston MA, US
    Yun Gao - Southborough MA, US
    Asimina Evangelinos - Chestnut Hill MA, US
    Louis Grenier - Brookline MA, US
    Roger Pak - Boxborough MA, US
    James Porter - Brighton MA, US
    James Wright - Lexington MA, US
  • International Classification:
    A61K 31/538
    C07D 487/02
  • US Classification:
    514183000, 540462000, 540461000
  • Abstract:
    The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

  • Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

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  • US Patent:
    20060019941, Jan 26, 2006
  • Filed:
    Jul 13, 2005
  • Appl. No.:
    11/180314
  • Inventors:
    Julian Adams - Boston MA, US
    Yun Gao - Southborough MA, US
    Asimina Evangelinos - Chestnut Hill MA, US
    Louis Grenier - Brookline MA, US
    Roger Pak - Boxborough MA, US
    James Porter - Brighton MA, US
    James Wright - Lexington MA, US
  • Assignee:
    Infinity Pharmaceuticals, Inc. - Cambridge MA
  • International Classification:
    A61K 31/33
  • US Classification:
    514183000, 540461000
  • Abstract:
    The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

  • Isoxazolidine Compounds For Treatment Of Bacterial Infections

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  • US Patent:
    20060020004, Jan 26, 2006
  • Filed:
    Jun 17, 2005
  • Appl. No.:
    11/155314
  • Inventors:
    Burton Christensen - Alamo CA, US
    Michael Foley - Chestnut Hill MA, US
    Asimina Georges Evangelinos - Andover MA, US
    Tao Liu - Ashland MA, US
    James Porter - Brighton MA, US
    Amy Ripka - Winthrop MA, US
    Linping Zhang - Lexington MA, US
  • Assignee:
    Infinity Pharmaceuticals, Inc. - Cambridge MA
  • International Classification:
    A61K 31/42
    C07D 261/10
    C07D 261/12
    C07D 413/02
  • US Classification:
    514378000, 548240000, 548243000
  • Abstract:
    The present invention relates to antibiotic compounds and intermediates useful in their preparation. Many of the antibiotic compounds contain a substituted isoxazolidine ring. The invention also relates to pharmaceutical compositions containing a compound of the invention. The invention further provides processes for the preparation of compounds of the invention, and methods for their use as therapeutic agents.

  • Compounds And Methods For Inhibiting The Interaction Of Bcl Proteins With Binding Partners

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  • US Patent:
    20060025460, Feb 2, 2006
  • Filed:
    Jun 17, 2005
  • Appl. No.:
    11/156364
  • Inventors:
    Alfredo Castro - Winchester MA, US
    Wei Deng - Lexington MA, US
    Kristopher Depew - Acton MA, US
    Michael Foley - Chestnut Hill MA, US
    Christian Fritz - Natick MA, US
    Asimina Georges Evangelinos - Andover MA, US
    Michael Grogan - Arlington MA, US
    Nafeeza Hafeez - West Roxbury MA, US
    Edward Holson - Newton Highlands MA, US
    Brian Hopkins - Brookline MA, US
    Nii Koney - Somerville MA, US
    Tao Liu - Ashland MA, US
    David Mann - Swampscott MA, US
    Lisa Marcaurelle - Arlington MA, US
    Daniel Snyder - Cambridge MA, US
    Dennis Underwood - Jamaica Plain MA, US
    Andrew Wylie - Brookline MA, US
    Lin-Chen Yu - Wollaston MA, US
    Linping Zhang - Lexington MA, US
  • Assignee:
    Infinity Pharmaceuticals, Inc. - Cambridge MA
  • International Classification:
    C07D 261/02
    A61K 31/42
  • US Classification:
    514378000, 548240000
  • Abstract:
    One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

  • Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

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  • US Patent:
    20090088414, Apr 2, 2009
  • Filed:
    Aug 27, 2008
  • Appl. No.:
    12/199415
  • Inventors:
    Julian Adams - Boston MA, US
    Yun Gao - Southborough MA, US
    Asimina T.Georges Evangelinos - Chestnut Hill MA, US
    Louis Grenier - Newton MA, US
    Roger H. Pak - Boxborough MA, US
    James R. Porter - Rowley MA, US
    James L. Wright - Lexington MA, US
  • International Classification:
    A61K 31/33
    C07D 225/06
  • US Classification:
    514183, 540461
  • Abstract:
    The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

  • Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

    view source
  • US Patent:
    20050227955, Oct 13, 2005
  • Filed:
    Dec 23, 2004
  • Appl. No.:
    11/022057
  • Inventors:
    Julian Adams - Boston MA, US
    Yun Gao - Southborough MA, US
    Asimina Evangelinos - Chestnut Hill MA, US
    Louis Grenier - Brookline MA, US
    Roger Pak - Boxborough MA, US
    James Porter - Brighton MA, US
    James Wright - Lexington MA, US
  • International Classification:
    A61K031/538
    A61K031/424
    C07D487/02
    C07D491/14
  • US Classification:
    514183000, 514229800, 514375000, 540461000
  • Abstract:
    The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

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