Arvia E Morris from 4535 Thackeray Pl, Seattle, WA 98105, age 67

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Location:

Seattle, WA

Industry:

Biotechnology

Work:

Amgen
Scientist

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Dna Encoding Cd40 Ligand, A Cytokine That Binds Cd40
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US Patent:

6410711, Jun 25, 2002
Filed:

Sep 20, 1999
Appl. No.:

09/399106
Inventors:

Richard J. Armitage - Bainbridge Island WA
William C. Fanslow - Normandy Park WA
Melanie K. Spriggs - Seattle WA
Subhashini Srinivasan - Greenbrae CA
Marylou G. Gibson - Carlsbad CA
Arvia E. Morris - Seattle WA
Jeffrey T. McGrew - Seattle WA
Assignee:

Immunex Corporation - Seattle WA
International Classification:

C12N 1519
US Classification:

536 235, 536 231, 536 234, 530350, 530351, 435 691, 435 695, 4352523, 4353201, 435455
Abstract:

There is disclosed a polypeptide (CD40-L) and DNA sequences, vectors and transformed host cells useful in providing CD40-L polypeptides. More particularly, this invention provides isolated human and murine CD40-L polypeptides that bind to the extracellular binding region of a CD40 receptor.

Methods And Host Cells For Improved Cell Culture
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US Patent:

6413744, Jul 2, 2002
Filed:

Aug 25, 2000
Appl. No.:

09/648667
Inventors:

Arvia E. Morris - Seattle WA
Assignee:

Immunex Corporation - Seattle WA
International Classification:

C12N 516
US Classification:

435 691, 435325, 435358, 435359, 435360, 435361, 435455
Abstract:

The invention provides improved methods of recombinant protein production in cell culture. More specifically, the invention relates to the modulation of the IGF-1 signaling pathway in cells so as to improve production characteristics.

Expression Augmenting Sequence Elements (Ease) For Eukaryotic Expression Systems
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US Patent:

6596514, Jul 22, 2003
Filed:

Oct 9, 2001
Appl. No.:

09/973928
Inventors:

Arvia E. Morris - Seattle WA
James N. Thomas - Redmond WA
Assignee:

Immunex Corporation - Seattle WA
International Classification:

C12P 1202
US Classification:

435 691, 435358, 4353201, 536 241
Abstract:

There are disclosed nucleotide sequences which can improve expression of recombinant proteins two- to eight-fold in stable cell pools when present in an expression vector.

Methods And Host Cells For Improved Cell Culture
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US Patent:

6897040, May 24, 2005
Filed:

Mar 29, 2002
Appl. No.:

10/109971
Inventors:

Arvia E. Morris - Seattle WA, US
Assignee:

Immunex Corporation - Seattle WA
International Classification:

C12N015/00
C12N015/85
C12N015/09
C12N001/19
C12P021/00
US Classification:

435 691, 435325, 435358, 435360, 435455, 4352542, 435 701, 435 697
Abstract:

The invention provides improved methods of recombinant protein production in cell culture. More specifically, the invention relates to the modulation of the IGF-1 signaling pathway in cells so as to improve production characteristics.

Regulation Of Translation For Recombinant Protein Production
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US Patent:

7091004, Aug 15, 2006
Filed:

Jun 7, 2002
Appl. No.:

10/165591
Inventors:

Arvia E. Morris - Seattle WA, US
Sharon T. Wong-Madden - Bellevue WA, US
Assignee:

Immunex Corporation - Seattle WA
International Classification:

C12P 21/06
C12N 5/00
C12N 15/63
US Classification:

435 691, 435325, 435358, 435359, 435360, 435361, 435455
Abstract:

The invention provides cells that produce increased levels of recombinant protein by modulating the activity of translational regulator gene products that are downstream targets of PKB alpha, methods of making such cells, and methods of using such cells. Such translational regulator gene products include 4E-BP1 and mTOR.

Methods And Host Cells For Improved Cell Culture
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US Patent:

7166445, Jan 23, 2007
Filed:

Feb 28, 2005
Appl. No.:

11/069122
Inventors:

Arvia E. Morris - Seattle WA, US
Assignee:

Immunex Corporation - Thousand Oaks CA
International Classification:

C12P 21/06
C12N 5/10
US Classification:

435 691, 435325, 435358, 435359, 435360, 435361, 435366, 4353721
Abstract:

The invention provides improved methods of recombinant protein production in cell culture. More specifically, the invention relates to the modulation of the IGF-1 signaling pathway in cells so as to improve production characteristics.

Feed Media
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US Patent:

8053236, Nov 8, 2011
Filed:

May 9, 2008
Appl. No.:

12/118459
Inventors:

Arvia Eleanor Morris - Seattle WA, US
Aurora Villegas Viaje - Lake Forest Park WA, US
Erika Pineda - Queretaro, MX
Assignee:

Amgen Inc. - Thousand Oaks CA
International Classification:

C12N 5/02
US Classification:

435404, 435 703, 435 711
Abstract:

The invention provides stable feed media containing pyruvate and methods for stabilizing feed media by adding pyruvate. The invention further provides methods for producing proteins using such media and proteins produced through the use of such methods.

Monkey Immunoglobulin Sequences
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US Patent:

20070212301, Sep 13, 2007
Filed:

Nov 4, 2004
Appl. No.:

10/578580
Inventors:

Teri Aldrich - Seattle WA, US
Wenyan Shen - Palo Alto CA, US
Frederick Jacobsen - Newbury Park CA, US
Arvia Morris - Seattle WA, US
Martin Allen - Seattle WA, US
Assignee:

AMGEN, INC. - Thousand Oaks CA
International Classification:

A61K 49/00
C07H 21/04
C07K 16/00
C12N 15/00
C12N 5/00
C12P 21/00
US Classification:

424009200, 435320100, 435325000, 435069100, 435069600, 530300000, 530387100, 536023530
Abstract:

Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain constant regions derived from cynomolgus monkeys. Chimeric antibodies with cynomolgus monkey constant regions are described.

Arvia E Morris