Arthur Rodney Olson

Author:

Arthur J. Olson

ISBN #:

0201581574

Author:

Arthur V. Olson

ISBN #:

0700222553

Author:

Arthur V. Olson

ISBN #:

0700223924

US Patent:

20100297009, Nov 25, 2010

Filed:

Mar 13, 2008

Appl. No.:

12/450114

Inventors:

Arthur Olson - Del Mar CA, US
Ehud Keinan - Timrat, IL

International Classification:

A61K 49/00
A61K 9/16
A61K 39/00
A61K 47/00
C07D 403/14
C07D 471/22
C07D 487/22

US Classification:

424 91, 424490, 4241841, 514788, 544296, 546 27, 548417, 977773, 977906, 977920, 977736, 977737

Abstract:

Self-assembled, closed and hollow chemical multimer structures having a dodecahedral morphology, composed of chemical monomers having a structurally symmetric core which possess a 5-fold rotational symmetry, are provided. Also provided are methods of creating such chemical monomers, methods of creating such chemical multimer structures and compositions comprising these chemical multimer structures. Also provided are uses of these chemical multimer structures in applications such as drug delivery, imaging, immunization, formation of plastic crystals and nanoparticle matrices and other medical and material science applications.

US Patent:

20100168439, Jul 1, 2010

Filed:

Mar 13, 2008

Appl. No.:

12/531292

Inventors:

Arthur J. Olson - DelMar CA, US

International Classification:

C07D 487/02

US Classification:

548417

Abstract:

Self-assembling multimeric physical models of closed polyhedral structures made of structurally symmetric units, and which mimic the structure and self-assembly characteristics of naturally occurring systems such as viral capsids, are provided. Also provided are methods of creating structurally symmetric units, kits for forming self-assembling physical models of polyhedral structures, and methods of forming the same.