Anthony Shaw

US Patent:

20210130289, May 6, 2021

Filed:

Jan 8, 2021

Appl. No.:

17/145109

Inventors:

- Menlo Park CA, US
Anthony Adrian SHAW - Redwood City CA, US

International Classification:

C07D 207/12
C07B 57/00

Abstract:

Provided herein are processes for making and methods of using salts of glycopyrronium, including solid forms and forms suitable for use as topicals. Disclosed here are processes for making salts of glycopyrronium, also processes for making compositions comprising salts of glycopyrronium, and methods of treating hyperhidrosis with salts of glycopyrronium as well as with compositions comprising salts of glycopyrronium such as, but not limited to, topical compositions. Disclosed herein are methods of treating hyperhidrosis including administering salts of glycopyrronium to subjects in need thereof.

US Patent:

20190161443, May 30, 2019

Filed:

Aug 1, 2017

Appl. No.:

16/320999

Inventors:

- Menlo Park CA, US
Anthony Adrian SHAW - Redwood City CA, US

International Classification:

C07D 207/12
C07B 57/00

Abstract:

Provided herein are processes for making and methods of using salts of glycopyrronium, including solid forms and forms suitable for use as topicals. Disclosed here are processes for making salts of glycopyrronium, also processes for making compositions comprising salts of glycopyrronium, and methods of treating hyperhidrosis with salts of glycopyrronium as well as with compositions comprising salts of glycopyrronium such as, but not limited to, topical compositions. Disclosed herein are methods of treating hyperhidrosis including administering salts of glycopyrronium to subjects in need thereof.

US Patent:

20170137815, May 18, 2017

Filed:

Jan 19, 2017

Appl. No.:

15/409819

Inventors:

- Cambridge MA, US
Francis GOSSELIN - San Mateo CA, US
Vasant R. JADHAV - Harleysville PA, US
Anthony W. SHAW - Harleysville PA, US
David M. TELLERS - Landsdale PA, US
Thomas J. TUCKER - North Wales PA, US
Yu YUAN - Orlando FL, US
Daniel ZEWGE - West Orange NJ, US

International Classification:

C12N 15/113

Abstract:

In an embodiment the instant invention discloses a modular composition comprising 1) an oligonucleotide; 2) one or more linkers, which may be the same or different, selected from Table 1, wherein the linkers are attached to the oligonucleotide at the 2′-position of the ribose rings and/or the terminal 3′- and/or 5′-positions of the oligonucleotide; 3) optionally, one or more peptides, which may be the same or different, selected from SEQ ID NOs: 1-59, wherein the peptides are attached to the linkers; and optionally one or more lipids, solubilizing groups and/or targeting ligands attached to the oligonucleotide.

US Patent:

20160074525, Mar 17, 2016

Filed:

Sep 8, 2015

Appl. No.:

14/848118

Inventors:

- Cambridge MA, US
Francis GOSSELIN - San Mateo CA, US
Vasant R. JADHAV - Harleysville PA, US
Anthony W. SHAW - Harleysville PA, US
David M. TELLERS - Landsdale PA, US
Thomas J. TUCKER - North Wales PA, US
Yu YUAN - Orlando FL, US
Daniel ZEWGE - West Orange NJ, US

International Classification:

A61K 47/48
C12N 15/113

Abstract:

In an embodiment the instant invention discloses a modular composition comprising 1) an oligonucleotide; 2) one or more linkers, which may be the same or different, selected from Table 1, wherein the linkers are attached to the oligonucleotide at the 2′-position of the ribose rings and/or the terminal 3′- and/or 5′-positions of the oligonucleotide; 3) optionally, one or more peptides, which may be the same or different, selected from SEQ ID NOs: 1-59, wherein the peptides are attached to the linkers; and optionally one or more lipids, solubilizing groups and/or targeting ligands attached to the oligonucleotide.

Author:

Anthony Shaw

ISBN #:

0760319383