Eileen White - Princeton NJ, US Anne Marie Strohecker - New York NY, US Robin Mathew - Monroe NJ, US Cristina Karp - North Brunswick NJ, US
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY - New Brunswick NJ
International Classification:
G01N 33/53 C12N 5/07
US Classification:
435 721, 435354
Abstract:
Methods for screening for modulators of autophagy are disclosed. Methods for identifying genes whose expression inhibits autophagy, as well as genes whose expression promotes autophagy, are disclosed. Also disclosed are methods for identifying compounds that stimulate autophagy, as well as compounds that inhibit autophagy. Cell lines that may be used in the methods of identification are also disclosed.
Cell Lines Useful For Assessing Modulation Of Autophagy
Eileen White - Princeton NJ, US Anne Marie Strohecker - New York NY, US Robin Mathew - Monroe NJ, US Cristina Karp - North Brunswick NJ, US
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY - New Brunswick NJ
International Classification:
C40B 30/06 C12Q 1/02
US Classification:
506 10, 435 29
Abstract:
Methods for screening for modulators of autophagy are disclosed. Methods for identifying genes whose expression inhibits autophagy, as well as genes whose expression promotes autophagy, are disclosed. Also disclosed are methods for identifying compounds that stimulate autophagy, as well as compounds that inhibit autophagy. Cell lines that may be used in the methods of identification are also disclosed.
Eileen White - Princeton NJ, US Anne M. Strohecker - North Plainfield NJ, US Richard Possemato - Brighton MA, US David M. Sabatini - Cambridge MA, US
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY - New Brunswick NJ
International Classification:
C12Q 1/02 G01N 33/53 C12Q 1/68
US Classification:
506 9, 435 613, 506 16, 506 18, 506 10
Abstract:
Methods for identifying compounds that inhibit or stimulate the autophagy pathway are described. Devices for detecting the expression of autophagy-related genes and kits for assaying the expression of autophagy-related genes are also described. Also described are methods for identifying individuals susceptible to or afflicted with a disease state associated with an autophagy pathway defect.
Resumes
Postdoctoral Fellow Cancer Institute Of New Jersey
Postdoctoral Fellow at The Cancer Institute of New Jersey
Location:
Greater New York City Area
Industry:
Biotechnology
Work:
The Cancer Institute of New Jersey since Apr 2008
Postdoctoral Fellow
Northwestern University - Department of Endcrinology/ Cryns Lab 2001 - 2007
Graduate Student
University of Southern California Jun 1999 - Sep 2001
Research Technician
Education:
Northwestern University - The Feinberg School of Medicine 2001 - 2007
PhD, Life Sciences/ Cancer Biology
Scripps College (Claremont, CA) 1995 - 1999
Rancho Cotate High School