Isolated DNA encoding each of human calcium channel -, -, - and -subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.
Michael M. Harpold - El Cajon CA Steven B. Ellis - San Diego CA Mark E. Williams - Carlsbad CA Ann F. McCue - La Mesa CA Alison Gillespie - San Diego CA Daniel H. Feldman - Gainesville FL Robert Brenner - Austin TX
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
C12N 1500
US Classification:
435 691, 536 235, 435325, 435354, 435356, 435358
Abstract:
Isolated DNA encoding each of human calcium channel -, -, - and -subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.
Michael M. Harpold - El Cajon CA, US Steven B. Ellis - San Diego CA, US Mark E. Williams - Carlsbad CA, US Ann F. McCue - La Mesa CA, US Alison Gillespie - San Diego CA, US Daniel H. Feldman - Gainesville FL, US Robert Brenner - Austin TX, US
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07K 14/435 C07K 14/705 C12P 21/02 A61K 38/17
US Classification:
530350, 514 2, 514 12, 536 235, 435 691
Abstract:
Isolated DNA encoding each of human calcium channel α, α, β- and γ-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.
Michael Harpold - El Cajon CA, US Steven Ellis - San Diego CA, US Mark Williams - Carlsbad CA, US Ann McCue - La Mesa CA, US Alison Gillespie - San Diego CA, US Daniel Feldman - Gainesville FL, US Robert Brenner - Austin TX, US
Isolated DNA encoding each of human calcium channel -, -, - and -subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.
Assays For Agonists And Antagonists Of Recombinant Human Calcium Channels
Michael M. Harpold - San Diego CA Steven B. Ellis - San Diego CA Mark E. Williams - Carlsbad CA Daniel H. Feldman - San Diego CA Ann F. McCue - La Mesa CA Robert Brenner - Austin TX
Assignee:
The Salk Institute Biotechnology/Industrial Assoc. Inc. - La Jolla CA
International Classification:
C12Q 102
US Classification:
435 4
Abstract:
Human calcium channel. alpha. sub. 1 -,. alpha. sub. 2 -,. beta. - and. gamma. -subunit encoding cDNAs, and related compositions and methods, are provided.
Dna Encoding Human Calcium Channel .Alpha.-.Sub.1A, .Beta..sub.1, .Beta.-.Sub.2, And .Beta.-.Sub.4 Subunits, And Assays Using Cells That Express The Subunits
Michael M. Harpold - El Cajon CA Steven B. Ellis - San Diego CA Mark E. Williams - Carlsbad CA Daniel H. Feldman - Gainesville FL Ann F. McCue - La Mesa CA Robert Brenner - Austin TX
Assignee:
Sibia Neurosciences. Inc. - La Jolla CA
International Classification:
C12N 1512 C12Q 102 C07K 14705
US Classification:
435 29
Abstract:
Isolated DNA encoding each of human calcium channel. alpha. sub. 1 -,. alpha. sub. 2 -,. beta. -and. gamma. -subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.
Human Calcium Channel .Alpha..sub.1, .Alpha..sub.2, And .Beta. Subunits And Assays Using Them
Michael M. Harpold - El Cajon CA Steven B. Ellis - San Diego CA Mark E. Williams - Carlsbad CA Daniel H. Feldman - Gainesville FL Ann F. McCue - La Mesa CA Robert Brenner - Austin TX
Assignee:
Sibia Neurosciences, Inc. - La Jolla CA
International Classification:
C12A 102 C07K 14705
US Classification:
435 29
Abstract:
Isolated DNA encoding each of human calcium channel. alpha. sub. 1 -,. alpha. sub. 2 -,. beta. - and. gamma. -subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.
Assays Of Cells Expressing Human Calcium Channels Containing .Alpha..sub.1 .Beta. Subunits
Michael M. Harpold - San Diego CA Steven B. Ellis - San Diego CA Mark E. Williams - Carlsbad CA Daniel H. Feldman - San Diego CA Ann F. McCue - La Mesa CA Robert Brenner - Austin TX
Assignee:
SIBIA Neurosciences, Inc. - La Jolla CA
International Classification:
C12Q 102 C12N 1512
US Classification:
435 29
Abstract:
Human calcium channel. alpha. sub. 1 -,. alpha. sub. 2 -,. beta. - and. gamma. -subunit encoding cDNAs, and related compositions and methods, are provided.
Health Alliance of the Hudson Valley Kingston, NY Feb 2012 to Oct 2013 Mental Health Evaluator/Partial Hospital Program AdvocateNorthkey Community Care Covington, KY Apr 2007 to Sep 2009 Social Worker/Crisis TherapistMobile Crisis Unit New York, NY Dec 2001 to Oct 2002 Visiting Nurse Service of New YorkMental Health Access Point (MHAP) Cincinnati, OH Aug 2000 to Sep 2001 Triage Clinician
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Live in Norderstedt, Music Star 12. April 2010 .
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