- Chicago IL, US Irvin Ho - Wilmette IL, US Lingdao Sha - Chicago IL, US Boleslaw Osinski - Chicago IL, US Aly Azeem Khan - Chicago IL, US Andrew J. Kruger - Chicago IL, US Michael Carlson - Chicago IL, US Abel Greenwald - Chicago IL, US Caleb Willis - Chicago IL, US Andrew Westley - Chicago IL, US Ryan Jones - Naperville IL, US Brett Mahon - Chicago IL, US
International Classification:
G16B 30/00 G16B 50/30 C12Q 1/6869
Abstract:
A method for qualifying a specimen prepared on one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and providing associated unstained slides for subsequent nucleic acid analysis is provided.
Determining Biomarkers From Histopathology Slide Images
- Chicago IL, US Irvin Ho - Wilmette IL, US Lingdao Sha - Chicago IL, US Boleslaw Osinski - Chicago IL, US Aly Azeem Khan - Chicago IL, US Andrew J. Kruger - Chicago IL, US Michael Carlson - Chicago IL, US Abel Greenwald - Chicago IL, US Caleb Willis - Chicago IL, US
A generalizable and interpretable deep learning model for predicting biomarker status and biomarker metrics from histopathology slide images is provided.
Predicting Total Nucleic Acid Yield And Dissection Boundaries For Histology Slides
- Chicago IL, US Irvin Ho - Wilmette IL, US Lingdao Sha - Chicago IL, US Boleslaw Osinski - Chicago IL, US Aly Azeem Khan - Chicago IL, US Andrew J. Kruger - Chicago IL, US Michael Carlson - Chicago IL, US Abel Greenwald - Chicago IL, US Caleb Willis - Chicago IL, US Andrew Westley - Chicago IL, US Ryan Jones - Naperville IL, US Brett Mahon - Chicago IL, US
International Classification:
G06T 7/00 G06T 7/37 G06K 9/00
Abstract:
A method for determining tumor block sufficiency for generating one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and determining a number of H&E slide for satisfying a desired total nucleic yield is provided.
Predicting Total Nucleic Acid Yield And Dissection Boundaries For Histology Slides
- Chicago IL, US Irvin Ho - Wilmette IL, US Lingdao Sha - Chicago IL, US Boleslaw Osinski - Chicago IL, US Aly Azeem Khan - Chicago IL, US Andrew J. Kruger - Chicago IL, US Michael Carlson - Chicago IL, US Abel Greenwald - Chicago IL, US Caleb Willis - Chicago IL, US Andrew Westley - Chicago IL, US Ryan Jones - Naperville IL, US Brett Mahon - Chicago IL, US
International Classification:
G06T 7/00 G06T 7/62 G06T 7/13 G06T 7/37
Abstract:
A method for predicting an expected yield of nucleic acid from tumor cells within a dissection boundary on a hematoxylin and eosin (H&E) slide is provided.
Predicting Total Nucleic Acid Yield And Dissection Boundaries For Histology Slides
- Chicago IL, US Irvin Ho - Wilmette IL, US Lingdao Sha - Chicago IL, US Boleslaw Osinski - Chicago IL, US Aly Azeem Khan - Chicago IL, US Andrew J. Kruger - Chicago IL, US Michael Carlson - Chicago IL, US Abel Greenwald - Chicago IL, US Caleb Willis - Chicago IL, US Andrew Westley - Chicago IL, US Ryan Jones - Naperville IL, US Brett Mahon - Chicago IL, US
International Classification:
G16B 30/00 C12Q 1/6869 G16B 50/30
Abstract:
A method for qualifying a specimen prepared on one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and providing associated unstained slides for subsequent nucleic acid analysis is provided.
Determining Biomarkers From Histopathology Slide Images
- Chicago IL, US Irvin Ho - Wilmette IL, US Lingdao Sha - Chicago IL, US Boleslaw Osinski - Chicago IL, US Aly Azeem Khan - Chicago IL, US Andrew J. Kruger - Chicago IL, US Michael Carlson - Chicago IL, US Abel Greenwald - Chicago IL, US Caleb Willis - Chicago IL, US
A generalizable and interpretable deep learning model for predicting biomarker status and biomarker metrics from histopathology slide images is provided.
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