George M. Hahn - Stanford CA Alie H. Saad - Menlo Park CA Amato J. Giaccia - Redwood City CA
Assignee:
Board of Trustees of the Leland Stanford Jr. University - Stanford CA
International Classification:
C12Q 116 G01N 2300
US Classification:
435 35
Abstract:
A method of assessing a cell's susceptibility to cell-damaging energy, such as ionizing radiation and heat, is disclosed. The method is based on measurable changes in voltage-dependent potassium channel currents in the cell in response to the energy. Also disclosed is a method for screening drugs which are effective to sensitize a cell to cell-damaging radiation.