514 44 A, 536 231, 4353201, 4352351, 435325, 506 16
Abstract:
The invention, in some aspects, relates to compositions and methods useful for modulating expression of miRNAs that are regulated by the TGF-β/BMP signaling pathway. In some aspects, the invention relates, to oligonucleotides comprising a CAGRN-motif that modulate expression of miRNAs that are regulated by TGF-β/BMP signaling pathway. The invention, in some aspects, relates to composition and methods useful for inhibiting microRNA processing. In some aspects, the invention relates to composition and methods for treating TGF-Beta/BMP mediated disorders.
Resumes
Professor At University Of California, San Francisco
University of California, San Francisco since Jun 2011
Professor
Tufts University School of Medicine Jul 2008 - May 2011
Associate Professor
Tufts university School of Medicine Jul 2000 - Jul 2008
Assistant Professor
Memorial Sloan-Kettering Cancer Center 1995 - 2000
Postdoctoral Fellow
Education:
Rockefeller University 1990 - 1995
PhD, Cell Biology
Skills:
Biochemistry Molecular Biology Cell Biology Cancer Animal Models Cell Cell Culture Genetics In Vitro Lifesciences Molecular Cloning Tissue Culture Western Blotting Signal Transduction Translational Research Cancer Research